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PolysacDB ID | 2419 |
Carbohydrate Name | Streptococcal A carbohydrate (Drugpedia) |
Carbohydrate Class | Capsular polysaccharide |
Microbe | Streptococcus Group A (NCBI Taxonomy) (Drugpedia) |
Basic Structure | N/A |
BCSDB Structure | N/A |
Proposed functions | This Carbohydrate is highly immunodominant |
Antigenic Nature used to produce antibodies | Sera of humans having IgM myeloma |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab AC8 |
Antibody type and class | IgM |
Assay System | Solid-phase enzyme-linked immunoassay, Streptococcal agglutination assay |
Cross-reactivity | AC8 agglutinated preferentially group A streptococci |
Proposed epitopes | AC8 appears to be specific for N-acetly-D-glucosamine (GlcNAc) side chains β(1-->2)-linked to rhamnose |
IEDB Epitope | 76687 |
Proposed Utility | N/A |
Curator ID | AA + AS |
Date of Curation | 07-05-2011 |
References | 2579417 |
PolysacDB ID | 2420 |
Carbohydrate Name | Streptococcal A carbohydrate (Drugpedia) |
Carbohydrate Class | Capsular polysaccharide |
Microbe | Streptococcus Group A (NCBI Taxonomy) (Drugpedia) |
Basic Structure | N/A |
BCSDB Structure | N/A |
Proposed functions | This Carbohydrate is highly immunodominant |
Antigenic Nature used to produce antibodies | Sera of humans having IgM myeloma |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab AC179 |
Antibody type and class | IgM |
Assay System | Solid-phase enzyme-linked immunoassay, Streptococcal agglutination assay |
Cross-reactivity | ACI79 was most active in agglutinating A variant (Av) and group C streptococci |
Proposed epitopes | AC179 is directed to α-linked rhamnose oligosaccharides |
IEDB Epitope | 76687 |
Proposed Utility | AC179 induced complement activation in the presence of the carbohydrate |
Curator ID | AA + AS |
Date of Curation | 07-05-2011 |
References | 2579417 |
PolysacDB ID | 2426 |
Carbohydrate Name | Streptococcal A carbohydrate (Drugpedia) |
Carbohydrate Class | Capsular polysaccharide |
Microbe | Streptococcus Group A (NCBI Taxonomy) (Drugpedia) |
Basic Structure | N/A |
BCSDB Structure | N/A |
Proposed functions | This Carbohydrate is highly immunodominant |
Antigenic Nature used to produce antibodies | Whole cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Antisera |
Antibody type and class | N/A |
Assay System | Radioimmunoassay |
Cross-reactivity | N/A |
Proposed epitopes | The antigenic determinant was known as α hapten that had a estimated molecular weight of 1100 daltons and a rhamnose: glucosamine molar ratio of 6:1 |
IEDB Epitope | 76687 |
Proposed Utility | N/A |
Curator ID | AA + AS |
Date of Curation | 10-05-2011 |
References | 4795261 |
Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036 |