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| PolysacDB ID | 2402 |
| Carbohydrate Name | Lipoteichoic acids (LTAs) (Drugpedia) |
| Carbohydrate Class | Glycolipid |
| Microbe | Streptococcus faecium 9790 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | LTAs are amphiphiles composed of a membrane lipid or glycolipid which is covalently linked to a linear chain of 15 to 30 polyglycerophosphate (PGP) units |
| BCSDB Structure | N/A |
| Proposed functions | Lipoteichoic acids (LTAs) are present on the surfaces of a majority of gram-positive bacteria and have been shown to constitute 1 to 2% of the dry weight of several organisms |
| Antigenic Nature used to produce antibodies | LTA preparation of S. faecium 9790. |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab 6D10 |
| Antibody type and class | IgM |
| Assay System | Haemagglutination |
| Cross-reactivity | This MAbs agglutinated SRBCs sensitized with S. faecium LTA but failed to agglutinate SRBCs sensitized with the LTAs from the other bacterial species |
| Proposed epitopes | This MAb was thought to be specific for the kojibiosyl substituents (glucose α-1-->2 glucose) present on the LTA of group D streptococci |
| IEDB Epitope | N/A |
| Proposed Utility | The anti-kojibiosyl MAbs would be useful as a specific reagent for identifying group D streptococci |
| Curator ID | AA + AS |
| Date of Curation | 01-05-2011 |
| References | PMC264251 |
| PolysacDB ID | 2403 |
| Carbohydrate Name | Lipoteichoic acids (LTAs) (Drugpedia) |
| Carbohydrate Class | Glycolipid |
| Microbe | Streptococcus faecium 9790 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | LTAs are amphiphiles composed of a membrane lipid or glycolipid which is covalently linked to a linear chain of 15 to 30 polyglycerophosphate (PGP) units |
| BCSDB Structure | N/A |
| Proposed functions | Lipoteichoic acids (LTAs) are present on the surfaces of a majority of gram-positive bacteria and have been shown to constitute 1 to 2% of the dry weight of several organisms |
| Antigenic Nature used to produce antibodies | LTA preparation of S. faecium 9790. |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab 9E5 |
| Antibody type and class | IgG1 |
| Assay System | Haemagglutination |
| Cross-reactivity | This MAbs agglutinated SRBCs sensitized with S. faecium LTA but failed to agglutinate SRBCs sensitized with the LTAs from the other bacterial species |
| Proposed epitopes | This MAb was thought to be specific for the kojibiosyl substituents (glucose α-1-->2 glucose) present on the LTA of group D streptococci |
| IEDB Epitope | N/A |
| Proposed Utility | The anti-kojibiosyl MAbs would be useful as a specific reagent for identifying group D streptococci |
| Curator ID | AA + AS |
| Date of Curation | 01-05-2011 |
| References | PMC264251 |
| PolysacDB ID | 2404 |
| Carbohydrate Name | Lipoteichoic acids (LTAs) (Drugpedia) |
| Carbohydrate Class | Glycolipid |
| Microbe | Streptococcus faecium 9790 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | LTAs are amphiphiles composed of a membrane lipid or glycolipid which is covalently linked to a linear chain of 15 to 30 polyglycerophosphate (PGP) units |
| BCSDB Structure | N/A |
| Proposed functions | Lipoteichoic acids (LTAs) are present on the surfaces of a majority of gram-positive bacteria and have been shown to constitute 1 to 2% of the dry weight of several organisms |
| Antigenic Nature used to produce antibodies | LTA preparation of S. faecium 9790. |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab 13G5 |
| Antibody type and class | IgM |
| Assay System | Haemagglutination |
| Cross-reactivity | This MAbs agglutinated SRBCs sensitized with S. faecium LTA but failed to agglutinate SRBCs sensitized with the LTAs from the other bacterial species |
| Proposed epitopes | This MAb was thought to be specific for the kojibiosyl substituents (glucose α-1-->2 glucose) present on the LTA of group D streptococci |
| IEDB Epitope | N/A |
| Proposed Utility | The anti-kojibiosyl MAbs would be useful as a specific reagent for identifying group D streptococci |
| Curator ID | AA + AS |
| Date of Curation | 01-05-2011 |
| References | PMC264251 |
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Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036 |