PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613

Total Entries - 16
Entry No. - 1 [TOP]

PolysacDB ID	2533
Carbohydrate Name	Lipopolysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Vibrio cholerae 47-4041 serotype Ogawa (NCBI Taxonomy) (Drugpedia)
Basic Structure	It is a linear unbranched homopolymer of 1,6-linked-D-galactopyranosyl residues.
BCSDB Structure	N/A
Proposed functions	V. cholerae lipopolysaccharide (LPS), a critical component of the outer membrane that is required for virulence, is a known target for immune responses following infection or immunization. Antibodies specific for V. cholerae LPS are correlated with protection against cholera
Antigenic Nature used to produce antibodies	Killed cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab OF1
Antibody type and class	IgG3
Assay System	Slide or microdilution agglutination methods, along with enzyme-linked immunosorbent assays and immunoblotting analysis
Cross-reactivity	This Mab reacted only with Ogawa-type V. cholerae
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab agglutinated both live and heat killed Ogawa cells
Curator ID	AA + AS
Date of Curation	19-06-2011
References	2448333

Entry No. - 2 [TOP]

PolysacDB ID	2534
Carbohydrate Name	Lipopolysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Vibrio cholerae 47-4041 serotype Ogawa (NCBI Taxonomy) (Drugpedia)
Basic Structure	It is a linear unbranched homopolymer of 1,6-linked-D-galactopyranosyl residues.
BCSDB Structure	N/A
Proposed functions	V. cholerae lipopolysaccharide (LPS), a critical component of the outer membrane that is required for virulence, is a known target for immune responses following infection or immunization. Antibodies specific for V. cholerae LPS are correlated with protection against cholera
Antigenic Nature used to produce antibodies	Killed cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab OF2
Antibody type and class	IgG3
Assay System	Slide or microdilution agglutination methods, along with enzyme-linked immunosorbent assays and immunoblotting analysis
Cross-reactivity	This Mab reacted only with Ogawa-type V. cholerae
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab agglutinated both live and heat killed Ogawa cells
Curator ID	AA + AS
Date of Curation	19-06-2011
References	2448333

Entry No. - 3 [TOP]

PolysacDB ID	2535
Carbohydrate Name	Lipopolysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Vibrio cholerae 47-4041 serotype Ogawa (NCBI Taxonomy) (Drugpedia)
Basic Structure	It is a linear unbranched homopolymer of 1,6-linked-D-galactopyranosyl residues.
BCSDB Structure	N/A
Proposed functions	V. cholerae lipopolysaccharide (LPS), a critical component of the outer membrane that is required for virulence, is a known target for immune responses following infection or immunization. Antibodies specific for V. cholerae LPS are correlated with protection against cholera
Antigenic Nature used to produce antibodies	Killed cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab OF3
Antibody type and class	IgG3
Assay System	Slide or microdilution agglutination methods, along with enzyme-linked immunosorbent assays and immunoblotting analysis
Cross-reactivity	This Mab reacted only with Ogawa-type V. cholerae
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab agglutinated both live and heat killed Ogawa cells
Curator ID	AA + AS
Date of Curation	19-06-2011
References	2448333

Entry No. - 4 [TOP]

PolysacDB ID	2536
Carbohydrate Name	Lipopolysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Vibrio cholerae 47-4041 serotype Ogawa (NCBI Taxonomy) (Drugpedia)
Basic Structure	It is a linear unbranched homopolymer of 1,6-linked-D-galactopyranosyl residues.
BCSDB Structure	N/A
Proposed functions	V. cholerae lipopolysaccharide (LPS), a critical component of the outer membrane that is required for virulence, is a known target for immune responses following infection or immunization. Antibodies specific for V. cholerae LPS are correlated with protection against cholera
Antigenic Nature used to produce antibodies	Killed cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab OF4
Antibody type and class	IgG3
Assay System	Slide or microdilution agglutination methods, along with enzyme-linked immunosorbent assays and immunoblotting analysis
Cross-reactivity	This Mab reacted only with Ogawa-type V. cholerae
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab agglutinated both live and heat killed Ogawa cells
Curator ID	AA + AS
Date of Curation	19-06-2011
References	2448333

Entry No. - 5 [TOP]

PolysacDB ID	2537
Carbohydrate Name	Lipopolysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Vibrio cholerae 47-4041 serotype Ogawa (NCBI Taxonomy) (Drugpedia)
Basic Structure	It is a linear unbranched homopolymer of 1,6-linked-D-galactopyranosyl residues.
BCSDB Structure	N/A
Proposed functions	V. cholerae lipopolysaccharide (LPS), a critical component of the outer membrane that is required for virulence, is a known target for immune responses following infection or immunization. Antibodies specific for V. cholerae LPS are correlated with protection against cholera
Antigenic Nature used to produce antibodies	Killed cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab OF5
Antibody type and class	IgG2b
Assay System	Slide or microdilution agglutination methods, along with enzyme-linked immunosorbent assays and immunoblotting analysis
Cross-reactivity	This Mab reacted only with Ogawa-type V. cholerae
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab agglutinated only live Ogawa cells and not heat killed cells
Curator ID	AA + AS
Date of Curation	19-06-2011
References	2448333

Entry No. - 6 [TOP]

PolysacDB ID	2538
Carbohydrate Name	Lipopolysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Vibrio cholerae 47-4041 serotype Ogawa (NCBI Taxonomy) (Drugpedia)
Basic Structure	It is a linear unbranched homopolymer of 1,6-linked-D-galactopyranosyl residues.
BCSDB Structure	N/A
Proposed functions	V. cholerae lipopolysaccharide (LPS), a critical component of the outer membrane that is required for virulence, is a known target for immune responses following infection or immunization. Antibodies specific for V. cholerae LPS are correlated with protection against cholera
Antigenic Nature used to produce antibodies	Killed cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab OF6
Antibody type and class	IgM
Assay System	Slide or microdilution agglutination methods, along with enzyme-linked immunosorbent assays and immunoblotting analysis
Cross-reactivity	This Mab reacted only with Ogawa-type V. cholerae
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab agglutinated only live Ogawa cells and not heat killed cells
Curator ID	AA + AS
Date of Curation	19-06-2011
References	2448333

Entry No. - 7 [TOP]

PolysacDB ID	2539
Carbohydrate Name	Lipopolysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Vibrio cholerae 47-4041 serotype Ogawa (NCBI Taxonomy) (Drugpedia)
Basic Structure	It is a linear unbranched homopolymer of 1,6-linked-D-galactopyranosyl residues.
BCSDB Structure	N/A
Proposed functions	V. cholerae lipopolysaccharide (LPS), a critical component of the outer membrane that is required for virulence, is a known target for immune responses following infection or immunization. Antibodies specific for V. cholerae LPS are correlated with protection against cholera
Antigenic Nature used to produce antibodies	Killed cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab OF7
Antibody type and class	IgM
Assay System	Slide or microdilution agglutination methods, along with enzyme-linked immunosorbent assays and immunoblotting analysis
Cross-reactivity	This Mab reacted only with Ogawa-type V. cholerae
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab agglutinated both live and heat killed Ogawa cells
Curator ID	AA + AS
Date of Curation	21-06-2011
References	2448333

Entry No. - 8 [TOP]

PolysacDB ID	2540
Carbohydrate Name	Lipopolysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Vibrio cholerae 47-4041 serotype Ogawa (NCBI Taxonomy) (Drugpedia)
Basic Structure	It is a linear unbranched homopolymer of 1,6-linked-D-galactopyranosyl residues.
BCSDB Structure	N/A
Proposed functions	V. cholerae lipopolysaccharide (LPS), a critical component of the outer membrane that is required for virulence, is a known target for immune responses following infection or immunization. Antibodies specific for V. cholerae LPS are correlated with protection against cholera
Antigenic Nature used to produce antibodies	Killed cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab OF8
Antibody type and class	IgM
Assay System	Slide or microdilution agglutination methods, along with enzyme-linked immunosorbent assays and immunoblotting analysis
Cross-reactivity	This Mab reacted only with Ogawa-type V. cholerae
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab agglutinated both live and heat killed Ogawa cells
Curator ID	AA + AS
Date of Curation	21-06-2011
References	2448333

Entry No. - 9 [TOP]

PolysacDB ID	2541
Carbohydrate Name	Lipopolysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Vibrio cholerae 47-4041 serotype Ogawa (NCBI Taxonomy) (Drugpedia)
Basic Structure	It is a linear unbranched homopolymer of 1,6-linked-D-galactopyranosyl residues.
BCSDB Structure	N/A
Proposed functions	V. cholerae lipopolysaccharide (LPS), a critical component of the outer membrane that is required for virulence, is a known target for immune responses following infection or immunization. Antibodies specific for V. cholerae LPS are correlated with protection against cholera
Antigenic Nature used to produce antibodies	Killed cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab OF9
Antibody type and class	IgM
Assay System	Slide or microdilution agglutination methods, along with enzyme-linked immunosorbent assays and immunoblotting analysis
Cross-reactivity	This Mab reacted only with Ogawa-type V. cholerae
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab agglutinated both live and heat killed Ogawa cells
Curator ID	AA + AS
Date of Curation	22-06-2011
References	2448333

Entry No. - 10 [TOP]

PolysacDB ID	2542
Carbohydrate Name	Lipopolysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Vibrio cholerae 47-4041 serotype Ogawa (NCBI Taxonomy) (Drugpedia)
Basic Structure	It is a linear unbranched homopolymer of 1,6-linked-D-galactopyranosyl residues.
BCSDB Structure	N/A
Proposed functions	V. cholerae lipopolysaccharide (LPS), a critical component of the outer membrane that is required for virulence, is a known target for immune responses following infection or immunization. Antibodies specific for V. cholerae LPS are correlated with protection against cholera
Antigenic Nature used to produce antibodies	Killed cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab OE1
Antibody type and class	IgG3
Assay System	Slide or microdilution agglutination methods, along with enzyme-linked immunosorbent assays and immunoblotting analysis
Cross-reactivity	This Mab reacted with both Ogawa- and Inaba-type V. cholerae
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab agglutinated both live and heat killed Ogawa and Inaba cells
Curator ID	AA + AS
Date of Curation	22-06-2011
References	2448333

Entry No. - 11 [TOP]

PolysacDB ID	2543
Carbohydrate Name	Lipopolysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Vibrio cholerae 47-4041 serotype Ogawa (NCBI Taxonomy) (Drugpedia)
Basic Structure	It is a linear unbranched homopolymer of 1,6-linked-D-galactopyranosyl residues.
BCSDB Structure	N/A
Proposed functions	V. cholerae lipopolysaccharide (LPS), a critical component of the outer membrane that is required for virulence, is a known target for immune responses following infection or immunization. Antibodies specific for V. cholerae LPS are correlated with protection against cholera
Antigenic Nature used to produce antibodies	Killed cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab OE2
Antibody type and class	IgG3
Assay System	Slide or microdilution agglutination methods, along with enzyme-linked immunosorbent assays and immunoblotting analysis
Cross-reactivity	This Mab reacted with both Ogawa- and Inaba-type V. cholerae
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab agglutinated both live and heat killed Ogawa and Inaba cells
Curator ID	AA + AS
Date of Curation	23-06-2011
References	2448333

Entry No. - 12 [TOP]

PolysacDB ID	2544
Carbohydrate Name	Lipopolysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Vibrio cholerae 47-4041 serotype Ogawa (NCBI Taxonomy) (Drugpedia)
Basic Structure	It is a linear unbranched homopolymer of 1,6-linked-D-galactopyranosyl residues.
BCSDB Structure	N/A
Proposed functions	V. cholerae lipopolysaccharide (LPS), a critical component of the outer membrane that is required for virulence, is a known target for immune responses following infection or immunization. Antibodies specific for V. cholerae LPS are correlated with protection against cholera
Antigenic Nature used to produce antibodies	Killed cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab OE3
Antibody type and class	IgG3
Assay System	Slide or microdilution agglutination methods, along with enzyme-linked immunosorbent assays and immunoblotting analysis
Cross-reactivity	This Mab reacted with both Ogawa- and Inaba-type V. cholerae
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab agglutinated both live and heat killed Ogawa and Inaba cells
Curator ID	AA + AS
Date of Curation	23-06-2011
References	2448333

Entry No. - 13 [TOP]

PolysacDB ID	2545
Carbohydrate Name	Lipopolysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Vibrio cholerae 47-4041 serotype Ogawa (NCBI Taxonomy) (Drugpedia)
Basic Structure	It is a linear unbranched homopolymer of 1,6-linked-D-galactopyranosyl residues.
BCSDB Structure	N/A
Proposed functions	V. cholerae lipopolysaccharide (LPS), a critical component of the outer membrane that is required for virulence, is a known target for immune responses following infection or immunization. Antibodies specific for V. cholerae LPS are correlated with protection against cholera
Antigenic Nature used to produce antibodies	Killed cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab OE4
Antibody type and class	IgG3
Assay System	Slide or microdilution agglutination methods, along with enzyme-linked immunosorbent assays and immunoblotting analysis
Cross-reactivity	This Mab reacted with both Ogawa- and Inaba-type V. cholerae
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab agglutinated both live and heat killed Ogawa and Inaba cells
Curator ID	AA + AS
Date of Curation	23-06-2011
References	2448333

Entry No. - 14 [TOP]

PolysacDB ID	2546
Carbohydrate Name	Lipopolysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Vibrio cholerae 47-4041 serotype Ogawa (NCBI Taxonomy) (Drugpedia)
Basic Structure	It is a linear unbranched homopolymer of 1,6-linked-D-galactopyranosyl residues.
BCSDB Structure	N/A
Proposed functions	V. cholerae lipopolysaccharide (LPS), a critical component of the outer membrane that is required for virulence, is a known target for immune responses following infection or immunization. Antibodies specific for V. cholerae LPS are correlated with protection against cholera
Antigenic Nature used to produce antibodies	Killed cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab OE5
Antibody type and class	IgG3
Assay System	Slide or microdilution agglutination methods, along with enzyme-linked immunosorbent assays and immunoblotting analysis
Cross-reactivity	This Mab reacted with both Ogawa- and Inaba-type V. cholerae
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab agglutinated both live and heat killed Ogawa and Inaba cells
Curator ID	AA + AS
Date of Curation	24-06-2011
References	2448333

Entry No. - 15 [TOP]

PolysacDB ID	2547
Carbohydrate Name	Lipopolysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Vibrio cholerae 47-4041 serotype Ogawa (NCBI Taxonomy) (Drugpedia)
Basic Structure	It is a linear unbranched homopolymer of 1,6-linked-D-galactopyranosyl residues.
BCSDB Structure	N/A
Proposed functions	V. cholerae lipopolysaccharide (LPS), a critical component of the outer membrane that is required for virulence, is a known target for immune responses following infection or immunization. Antibodies specific for V. cholerae LPS are correlated with protection against cholera
Antigenic Nature used to produce antibodies	Killed cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab OE6
Antibody type and class	IgG3
Assay System	Slide or microdilution agglutination methods, along with enzyme-linked immunosorbent assays and immunoblotting analysis
Cross-reactivity	This Mab reacted with both Ogawa- and Inaba-type V. cholerae
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab agglutinated both live and heat killed Ogawa and Inaba cells
Curator ID	AA + AS
Date of Curation	24-06-2011
References	2448333

Entry No. - 16 [TOP]

PolysacDB ID	2548
Carbohydrate Name	Lipopolysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Vibrio cholerae 47-4041 serotype Ogawa (NCBI Taxonomy) (Drugpedia)
Basic Structure	It is a linear unbranched homopolymer of 1,6-linked-D-galactopyranosyl residues.
BCSDB Structure	N/A
Proposed functions	V. cholerae lipopolysaccharide (LPS), a critical component of the outer membrane that is required for virulence, is a known target for immune responses following infection or immunization. Antibodies specific for V. cholerae LPS are correlated with protection against cholera
Antigenic Nature used to produce antibodies	Killed cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab OE7
Antibody type and class	IgG1
Assay System	Slide or microdilution agglutination methods, along with enzyme-linked immunosorbent assays and immunoblotting analysis
Cross-reactivity	This Mab reacted with both Ogawa- and Inaba-type V. cholerae
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab agglutinated only live and not heat killed Ogawa and Inaba cells
Curator ID	AA + AS
Date of Curation	24-06-2011
References	2448333

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