PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
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PolysacDB ID2425
Carbohydrate NameCell wall polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
Microbe NameStreptococcus mutans LM7 Serotype e   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureWhole cells
Carrier NameNil
Conjugate MethodNil
AntibodiesMab S3-9
Antibody Type ClassIgM
Assay SystemRadioimmunoassay, Immunodiffusion tests
Cross ReactivityMab S3-9 reacted with hot-saline extracts of strain LM7, MT703, and P4 (type e) cells but did not react at all with extracts of other S. mutans strains
Proposed Epitopeβ-glucosyl moiety of the e-polysaccharide seemed to make up the immunodominant region
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used for immunodetection of serotype e Streptococcal cells
Curator IDAA + AS
Date of Curation09-05-2011
ReferencesPMC261049

Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036