PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
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PolysacDB ID1536
Carbohydrate NameExcreted Factor [EF] antigen   (Drugpedia)
Carbohydrate ClassGlycoprotein
Microbe NameLeishmania tropica major   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureGlutaraldehyde-fixed promastigotes
Carrier NameNil
Conjugate MethodNil
AntibodiesMab WIC 79.3
Antibody Type ClassIgG1
Assay SystemImmunodiffusion
Cross ReactivityThis Mab was quite specific and reacted only with EFs of serotype Al and A4 [Israeli and Russian L. tropica major]
Proposed EpitopeN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab would help in the serotyping of Leishmania species
Curator IDAA + AS
Date of Curation27-08-2010
ReferencesPMC270766

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PolysacDB ID1537
Carbohydrate NameExcreted Factor [EF] antigen   (Drugpedia)
Carbohydrate ClassGlycoprotein
Microbe NameLeishmania tropica major   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureLethally irradiated promastigotes
Carrier NameNil
Conjugate MethodNil
AntibodiesMab WIC 108.2
Antibody Type ClassIgM
Assay SystemImmunodiffusion
Cross ReactivityThis Mab was quite specific and reacted only with EFs of serotype Al and A4 [Israeli and Russian L. tropica major]
Proposed EpitopeN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab would help in the serotyping of Leishmania species
Curator IDAA + AS
Date of Curation28-08-2010
ReferencesPMC270766

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PolysacDB ID1538
Carbohydrate NameExcreted Factor [EF] antigen   (Drugpedia)
Carbohydrate ClassGlycoprotein
Microbe NameLeishmania tropica major   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureLethally irradiated promastigotes
Carrier NameNil
Conjugate MethodNil
AntibodiesMab WIC 108.3
Antibody Type ClassIgG1
Assay SystemImmunodiffusion
Cross ReactivityThis Mab reacted with EFs of serotype Al and A4 [Israeli and Russian L. tropica major] and also with L. mexicana, Leishmania aethiopica, and Leishmania enriettii
Proposed EpitopeN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab would help in the serotyping of Leishmania species
Curator IDAA + AS
Date of Curation01-09-2010
ReferencesPMC270766

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PolysacDB ID1539
Carbohydrate NameExcreted Factor [EF] antigen   (Drugpedia)
Carbohydrate ClassGlycoprotein
Microbe NameLeishmania tropica major   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureLethally irradiated promastigotes
Carrier NameNil
Conjugate MethodNil
AntibodiesMab WIC 108.7
Antibody Type ClassIgM
Assay SystemImmunodiffusion
Cross ReactivityThis Mab reacted with EFs of serotype Al and A4 [Israeli and Russian L. tropica major] and also with L. mexicana, Leishmania aethiopica, L. tropica minor and Leishmania enriettii
Proposed EpitopeN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab would help in the serotyping of Leishmania species
Curator IDAA + AS
Date of Curation01-09-2010
ReferencesPMC270766

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PolysacDB ID1540
Carbohydrate NameExcreted Factor [EF] antigen   (Drugpedia)
Carbohydrate ClassGlycoprotein
Microbe NameLeishmania tropica major   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureLiving promastigotes
Carrier NameNil
Conjugate MethodNil
AntibodiesPolysera
Antibody Type ClassIgG and IgM
Assay SystemImmunodiffusion
Cross ReactivityThe antisera cross-reacted with Israeli and Russian L. tropica major, L. mexicana, Leishmania aethiopica, and Leishmania enriettii and L. tropica minor
Proposed EpitopeN/A
IEDB EpitopeN/A
Proposed UtilityThis antisera would help in the serotyping of Leishmania species
Curator IDAA + AS
Date of Curation02-09-2010
ReferencesPMC270766

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