PolysacDB ID | 1263 |
Carbohydrate Name | Glucomannoprotein (Drugpedia) |
Carbohydrate Class | Glycoprotein |
Microbe Name | Candida albicans serotype A (NCBI Taxonomy) (Drugpedia) |
Basic Structure | N/A
|
BCSDB Structure | N/A |
Proposed Function | N/A |
Antigenic Nature | Glucomannoprotein-rich antigenic extract (GMP) |
Carrier Name | Nil |
Conjugate Method | Nil |
Antibodies | Mab AF-1 |
Antibody Type Class | IgM |
Assay System | ELISA, immunofluorescence and slide agglutination tests |
Cross Reactivity | This Mab cross-reacted with C. albicans serotypes A and B, C. tropicalis, C. guilliermondii and C. viswanathii, but did not cross-react with C. krusei, C. parapsilosis, C. kefyr (pseudotropicalis) and T. Glabrata |
Proposed Epitope | The epitope was proposed to consist of mannan residues |
IEDB Epitope | N/A |
Proposed Utility | This Mab had strong agglutination properties for Candida species. This Mab helped in the identification of new polysaccharide epitopes on the cell wall of pathogenic Candida species. |
Curator ID | AA + AS |
Date of Curation | 02-05-2010
|
References | 2462051 |