PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
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PolysacDB ID1328
Carbohydrate NameGlycan fraction   (Drugpedia)
Carbohydrate ClassGlycoprotein
Microbe NameCandida albicans B311   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureWhole cells
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 4G8
Antibody Type ClassIgM
Assay SystemELISA, immunofluorescence, crossed immunoelectrophoresis
Cross ReactivityThis antibody cross-reacted with 5 strains of Candida albicans and also cross-reacted with Candida tropicalis and Candida stellatoidia and S. cerevisae but did not cross-react with T. glabrata
Proposed EpitopeN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used to isolate surface components and determine the chemical structures that are responsible for the immunological differences. This Mab would facilitate the development of serological assays
Curator IDAA + AS
Date of Curation13-06-2010
ReferencesPMC259333

Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036