PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

Home | Search | Advance Search | Browse | Online Submission | Documentation & FAQ | Team | Contact us

Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
   
Page - 1 of 2

Record - 1 of 32   [TOP]

PolysacDB ID1663
Carbohydrate NameGlycopeptidolipid antigen   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium avium complex serovar 4   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThis antigen is composed of a glycosylated lipopeptide core, fatty acyl-D-phenylalanine-D-allothreonine-D-alanine-L-alaninyl-O-(3,4-di-O-methyl-α-L-rhamnopyranoside), to which a haptenic oligosaccharide is linked at the threonine substituent
BCSDB Structure134896
Proposed FunctionThis oligosaccharide unit is the source of the dominant immunogenicity of members of the M. avium complex, i.e., their characteristic agglutinability and type specificity
Antigenic NatureSerovar 4-specific neoglycoprotein, 4-0-methyl-a-L-rhamnopyranosyl(1--> 4)-2-0 - methyl - alpha - L fucopyranosyl oxynonanoyl-bovine serum albumin (BSA) (neoantigen 4) along with whole washed M. avium complex serovar 4 cells and corresponding serovar 4 glycopeptidolipid antigens
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 32B8
Antibody Type ClassIgG3
Assay SystemELISA, Inhibition assays, dot blot
Cross ReactivityThis antibody cross-reacted with whole cells of serovar 4, acetylated-GPL-4, and GPL-4
Proposed Epitope4-O-methyl-α-L-rhamnopyranosyl-(1-->4)-2-O-methyl-α-L-fucopyranosyl residues seemed to be a part of the epitope
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used for the identification and classification of M. avium isolates. This Mab can be applied directly to bacterial cultures, thus allowing easy, rapid identification of at least half of the M. avium isolates encountered in the clinical laboratory
Curator IDAA + AS
Date of Curation01-10-2010
ReferencesPMC260783

Record - 2 of 32   [TOP]

PolysacDB ID1664
Carbohydrate NameGlycopeptidolipid antigen   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium avium complex serovar 4   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThis antigen is composed of a glycosylated lipopeptide core, fatty acyl-D-phenylalanine-D-allothreonine-D-alanine-L-alaninyl-O-(3,4-di-O-methyl-α-L-rhamnopyranoside), to which a haptenic oligosaccharide is linked at the threonine substituent
BCSDB Structure134896
Proposed FunctionThis oligosaccharide unit is the source of the dominant immunogenicity of members of the M. avium complex, i.e., their characteristic agglutinability and type specificity
Antigenic NatureSerovar 4-specific neoglycoprotein, 4-0-methyl-a-L-rhamnopyranosyl(1--> 4)-2-0 - methyl - alpha - L fucopyranosyl oxynonanoyl-bovine serum albumin (BSA) (neoantigen 4) along with whole washed M. avium complex serovar 4 cells and corresponding serovar 4 glycopeptidolipid antigens
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 33F7
Antibody Type ClassIgG3
Assay SystemELISA, Inhibition assays, dot blot
Cross ReactivityThis antibody cross-reacted with whole cells of serovar 4, acetylated-GPL-4, and GPL-4
Proposed Epitope4-O-methyl-α-L-rhamnopyranosyl-(1-->4)-2-O-methyl-α-L-fucopyranosyl residues seemed to be a part of the epitope
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used for the identification and classification of M. avium isolates. This Mab can be applied directly to bacterial cultures, thus allowing easy, rapid identification of at least half of the M. avium isolates encountered in the clinical laboratory
Curator IDAA + AS
Date of Curation02-10-2010
ReferencesPMC260783

Record - 3 of 32   [TOP]

PolysacDB ID1665
Carbohydrate NameGlycopeptidolipid antigen   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium avium complex serovar 4   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThis antigen is composed of a glycosylated lipopeptide core, fatty acyl-D-phenylalanine-D-allothreonine-D-alanine-L-alaninyl-O-(3,4-di-O-methyl-α-L-rhamnopyranoside), to which a haptenic oligosaccharide is linked at the threonine substituent
BCSDB Structure134896
Proposed FunctionThis oligosaccharide unit is the source of the dominant immunogenicity of members of the M. avium complex, i.e., their characteristic agglutinability and type specificity
Antigenic NatureSerovar 4-specific neoglycoprotein, 4-0-methyl-a-L-rhamnopyranosyl(1--> 4)-2-0 - methyl - alpha - L fucopyranosyl oxynonanoyl-bovine serum albumin (BSA) (neoantigen 4) along with whole washed M. avium complex serovar 4 cells and corresponding serovar 4 glycopeptidolipid antigens
Carrier NameNil
Conjugate MethodNil
AntibodiesMab F85-6
Antibody Type ClassIgG3
Assay SystemELISA, Inhibition assays, dot blot
Cross ReactivityThis antibody cross-reacted with whole cells of serovar 4 and acetylated-GPL-4
Proposed Epitope4-O-methyl-α-L-rhamnopyranosyl-(1-->4)-2-O-methyl-α-L-fucopyranosyl residues seemed to be a part of the epitope
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used for the identification and classification of M. avium isolates. This Mab can be applied directly to bacterial cultures, thus allowing easy, rapid identification of at least half of the M. avium isolates encountered in the clinical laboratory
Curator IDAA + AS
Date of Curation02-10-2010
ReferencesPMC260783

Record - 4 of 32   [TOP]

PolysacDB ID1666
Carbohydrate NameGlycopeptidolipid antigen   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium avium complex serovar 4   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThis antigen is composed of a glycosylated lipopeptide core, fatty acyl-D-phenylalanine-D-allothreonine-D-alanine-L-alaninyl-O-(3,4-di-O-methyl-α-L-rhamnopyranoside), to which a haptenic oligosaccharide is linked at the threonine substituent
BCSDB Structure134896
Proposed FunctionThis oligosaccharide unit is the source of the dominant immunogenicity of members of the M. avium complex, i.e., their characteristic agglutinability and type specificity
Antigenic NatureSerovar 4-specific neoglycoprotein, 4-0-methyl-a-L-rhamnopyranosyl(1--> 4)-2-0 - methyl - alpha - L fucopyranosyl oxynonanoyl-bovine serum albumin (BSA) (neoantigen 4) along with whole washed M. avium complex serovar 4 cells and corresponding serovar 4 glycopeptidolipid antigens
Carrier NameNil
Conjugate MethodNil
AntibodiesMab F85-5
Antibody Type ClassIgG3
Assay SystemELISA, Inhibition assays, dot blot
Cross ReactivityThis antibody cross-reacted with whole cells of serovar 4 and acetylated-GPL-4
Proposed Epitope4-O-methyl-α-L-rhamnopyranosyl-(1-->4)-2-O-methyl-α-L-fucopyranosyl residues seemed to be a part of the epitope
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used for the identification and classification of M. avium isolates. This Mab can be applied directly to bacterial cultures, thus allowing easy, rapid identification of at least half of the M. avium isolates encountered in the clinical laboratory
Curator IDAA + AS
Date of Curation02-10-2010
ReferencesPMC260783

Record - 5 of 32   [TOP]

PolysacDB ID1667
Carbohydrate NameGlycopeptidolipid antigen   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium avium complex serovar 4   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThis antigen is composed of a glycosylated lipopeptide core, fatty acyl-D-phenylalanine-D-allothreonine-D-alanine-L-alaninyl-O-(3,4-di-O-methyl-α-L-rhamnopyranoside), to which a haptenic oligosaccharide is linked at the threonine substituent
BCSDB Structure134896
Proposed FunctionThis oligosaccharide unit is the source of the dominant immunogenicity of members of the M. avium complex, i.e., their characteristic agglutinability and type specificity
Antigenic NatureSerovar 4-specific neoglycoprotein, 4-0-methyl-a-L-rhamnopyranosyl(1--> 4)-2-0 - methyl - alpha - L fucopyranosyl oxynonanoyl-bovine serum albumin (BSA) (neoantigen 4) along with whole washed M. avium complex serovar 4 cells and corresponding serovar 4 glycopeptidolipid antigens
Carrier NameNil
Conjugate MethodNil
AntibodiesMab F85-3
Antibody Type ClassIgG3
Assay SystemELISA, Inhibition assays, dot blot
Cross ReactivityThis antibody cross-reacted with whole cells of serovar 4 and acetylated-GPL-4
Proposed Epitope4-O-methyl-α-L-rhamnopyranosyl-(1-->4)-2-O-methyl-α-L-fucopyranosyl residues seemed to be a part of the epitope
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used for the identification and classification of M. avium isolates. This Mab can be applied directly to bacterial cultures, thus allowing easy, rapid identification of at least half of the M. avium isolates encountered in the clinical laboratory
Curator IDAA + AS
Date of Curation02-10-2010
ReferencesPMC260783

Record - 6 of 32   [TOP]

PolysacDB ID1668
Carbohydrate NameGlycopeptidolipid antigen   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium avium complex serovar 1   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThis antigen is composed of a glycosylated lipopeptide core, fatty acyl-D-phenylalanine-D-allothreonine-D-alanine-L-alaninyl-O-(3,4-di-O-methyl-α-L-rhamnopyranoside), to which a haptenic oligosaccharide is linked at the threonine substituent
BCSDB StructureN/A
Proposed FunctionThis oligosaccharide unit is the source of the dominant immunogenicity of members of the M. avium complex, i.e., their characteristic agglutinability and type specificity
Antigenic NatureWhole cells combined with whole unfractionated lipid
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 3F6
Antibody Type ClassIgG3
Assay SystemELISA, Inhibition assays, dot blot
Cross ReactivityThis antibody cross-reacted with whole cells of serovar 1 and acetylated-GPL-1
Proposed EpitopeDistal O-acetyl-α-L-rhamnopyranosyl residues seemed to be a part of the epitope
IEDB Epitope76726
Proposed UtilityThis Mab can be used for the identification and classification of M. avium isolates. This Mab can be applied directly to bacterial cultures, thus allowing easy, rapid identification of at least half of the M. avium isolates encountered in the clinical laboratory
Curator IDAA + AS
Date of Curation03-10-2010
ReferencesPMC260783

Record - 7 of 32   [TOP]

PolysacDB ID1669
Carbohydrate NameGlycopeptidolipid antigen   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium avium complex serovar 1   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThis antigen is composed of a glycosylated lipopeptide core, fatty acyl-D-phenylalanine-D-allothreonine-D-alanine-L-alaninyl-O-(3,4-di-O-methyl-α-L-rhamnopyranoside), to which a haptenic oligosaccharide is linked at the threonine substituent
BCSDB StructureN/A
Proposed FunctionThis oligosaccharide unit is the source of the dominant immunogenicity of members of the M. avium complex, i.e., their characteristic agglutinability and type specificity
Antigenic NatureWhole cells combined with whole unfractionated lipid
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 4C6
Antibody Type ClassIgM
Assay SystemELISA, Inhibition assays, dot blot
Cross ReactivityThis antibody cross-reacted with whole cells of serovar 1 and acetylated-GPL-1
Proposed EpitopeDistal O-acetyl-α-L-rhamnopyranosyl residues seemed to be a part of the epitope
IEDB Epitope76726
Proposed UtilityThis Mab can be used for the identification and classification of M. avium isolates. This Mab can be applied directly to bacterial cultures, thus allowing easy, rapid identification of at least half of the M. avium isolates encountered in the clinical laboratory
Curator IDAA + AS
Date of Curation03-10-2010
ReferencesPMC260783

Record - 8 of 32   [TOP]

PolysacDB ID1670
Carbohydrate NameGlycopeptidolipid antigen   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium avium complex serovar 2   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThis antigen is composed of a glycosylated lipopeptide core, fatty acyl-D-phenylalanine-D-allothreonine-D-alanine-L-alaninyl-O-(3,4-di-O-methyl-α-L-rhamnopyranoside), to which a haptenic oligosaccharide is linked at the threonine substituent
BCSDB StructureN/A
Proposed FunctionThis oligosaccharide unit is the source of the dominant immunogenicity of members of the M. avium complex, i.e., their characteristic agglutinability and type specificity
Antigenic NatureWhole cells combined with whole unfractionated lipid
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 123.4
Antibody Type ClassIgG2a
Assay SystemELISA, Inhibition assays, dot blot
Cross ReactivityThis antibody cross-reacted with whole cells of serovar 2 and acetylated-GPL-2
Proposed Epitope4-O-acetyl-2,3-di-O-methyl-α-L-fucopyranose residues seemed to be a part of the epitope
IEDB Epitope76852
Proposed UtilityThis Mab can be used for the identification and classification of M. avium isolates. This Mab can be applied directly to bacterial cultures, thus allowing easy, rapid identification of at least half of the M. avium isolates encountered in the clinical laboratory
Curator IDAA + AS
Date of Curation03-10-2010
ReferencesPMC260783

Record - 9 of 32   [TOP]

PolysacDB ID1671
Carbohydrate NameGlycopeptidolipid antigen   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium avium complex serovar 8   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThis antigen is composed of a glycosylated lipopeptide core, fatty acyl-D-phenylalanine-D-allothreonine-D-alanine-L-alaninyl-O-(3,4-di-O-methyl-α-L-rhamnopyranoside), to which a haptenic oligosaccharide is linked at the threonine substituent
BCSDB Structure109375
Proposed FunctionThis oligosaccharide unit is the source of the dominant immunogenicity of members of the M. avium complex, i.e., their characteristic agglutinability and type specificity
Antigenic NatureWhole cells combined with whole unfractionated lipid
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 5F7
Antibody Type ClassIgG3
Assay SystemELISA, Inhibition assays, dot blot
Cross ReactivityThis antibody cross-reacted with whole cells of serovar 8, acetylated-GPL-8, and GPL-8
Proposed Epitope4,6-(l'-carboxyethylidene)-3-0-methyl-beta-D-glucopyranosyl residues seemed to be a part of the epitope
IEDB Epitope76853
Proposed UtilityThis Mab can be used for the identification and classification of M. avium isolates. This Mab can be applied directly to bacterial cultures, thus allowing easy, rapid identification of at least half of the M. avium isolates encountered in the clinical laboratory
Curator IDAA + AS
Date of Curation03-10-2010
ReferencesPMC260783

Record - 10 of 32   [TOP]

PolysacDB ID1672
Carbohydrate NameGlycopeptidolipid antigen   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium avium complex serovar 8   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThis antigen is composed of a glycosylated lipopeptide core, fatty acyl-D-phenylalanine-D-allothreonine-D-alanine-L-alaninyl-O-(3,4-di-O-methyl-α-L-rhamnopyranoside), to which a haptenic oligosaccharide is linked at the threonine substituent
BCSDB Structure109375
Proposed FunctionThis oligosaccharide unit is the source of the dominant immunogenicity of members of the M. avium complex, i.e., their characteristic agglutinability and type specificity
Antigenic NatureWhole cells combined with whole unfractionated lipid
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 2B8
Antibody Type ClassIgG3
Assay SystemELISA, Inhibition assays, dot blot
Cross ReactivityThis antibody cross-reacted with whole cells of serovar 8, acetylated-GPL-8, and GPL-8
Proposed Epitope4,6-(l'-carboxyethylidene)-3-0-methyl-beta-D-glucopyranosyl residues seemed to be a part of the epitope
IEDB Epitope76853
Proposed UtilityThis Mab can be used for the identification and classification of M. avium isolates. This Mab can be applied directly to bacterial cultures, thus allowing easy, rapid identification of at least half of the M. avium isolates encountered in the clinical laboratory
Curator IDAA + AS
Date of Curation03-10-2010
ReferencesPMC260783

Record - 11 of 32   [TOP]

PolysacDB ID1673
Carbohydrate NameGlycopeptidolipid antigen   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium avium complex serovar 8   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThis antigen is composed of a glycosylated lipopeptide core, fatty acyl-D-phenylalanine-D-allothreonine-D-alanine-L-alaninyl-O-(3,4-di-O-methyl-α-L-rhamnopyranoside), to which a haptenic oligosaccharide is linked at the threonine substituent
BCSDB Structure109375
Proposed FunctionThis oligosaccharide unit is the source of the dominant immunogenicity of members of the M. avium complex, i.e., their characteristic agglutinability and type specificity
Antigenic NatureWhole cells combined with whole unfractionated lipid
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 4D7
Antibody Type ClassIgG3
Assay SystemELISA, Inhibition assays, dot blot
Cross ReactivityThis antibody cross-reacted with whole cells of serovar 8, acetylated-GPL-8, GPL-8, acetylated GPL-21, and GPL-21
Proposed Epitope4,6-(l'-carboxyethylidene)-3-0-methyl-beta-D-glucopyranosyl residues seemed to be a part of the epitope
IEDB Epitope76853
Proposed UtilityThis Mab can be used for the identification and classification of M. avium isolates. This Mab can be applied directly to bacterial cultures, thus allowing easy, rapid identification of at least half of the M. avium isolates encountered in the clinical laboratory
Curator IDAA + AS
Date of Curation04-10-2010
ReferencesPMC260783

Record - 12 of 32   [TOP]

PolysacDB ID1674
Carbohydrate NameGlycopeptidolipid antigen   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium avium complex serovar 9   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThis antigen is composed of a glycosylated lipopeptide core, fatty acyl-D-phenylalanine-D-allothreonine-D-alanine-L-alaninyl-O-(3,4-di-O-methyl-α-L-rhamnopyranoside), to which a haptenic oligosaccharide is linked at the threonine substituent
BCSDB Structure133663
Proposed FunctionThis oligosaccharide unit is the source of the dominant immunogenicity of members of the M. avium complex, i.e., their characteristic agglutinability and type specificity
Antigenic NatureWhole washed heat-killed bacteria
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 5210
Antibody Type ClassIgG3
Assay SystemELISA, Inhibition assays, dot blot
Cross ReactivityThis antibody cross-reacted with Whole cells of serovar 9 and acetylated-GPL-9
Proposed Epitope4-O-acetyl-2,3-di-O-methyl-α-L-fucopyranosyl-(1-->4)-β-D-glucuronopyranosyl residues seemed to be the part of the epitope
IEDB Epitope76769
Proposed UtilityThis Mab can be used for the identification and classification of M. avium isolates. This Mab can be applied directly to bacterial cultures, thus allowing easy, rapid identification of at least half of the M. avium isolates encountered in the clinical laboratory
Curator IDAA + AS
Date of Curation04-10-2010
ReferencesPMC260783

Record - 13 of 32   [TOP]

PolysacDB ID1675
Carbohydrate NameGlycopeptidolipid antigen   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium avium complex serovar 9   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThis antigen is composed of a glycosylated lipopeptide core, fatty acyl-D-phenylalanine-D-allothreonine-D-alanine-L-alaninyl-O-(3,4-di-O-methyl-α-L-rhamnopyranoside), to which a haptenic oligosaccharide is linked at the threonine substituent
BCSDB Structure133663
Proposed FunctionThis oligosaccharide unit is the source of the dominant immunogenicity of members of the M. avium complex, i.e., their characteristic agglutinability and type specificity
Antigenic NatureWhole washed heat-killed bacteria
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 5214
Antibody Type ClassIgG3
Assay SystemELISA, Inhibition assays, dot blot
Cross ReactivityThis antibody cross-reacted with Whole cells of serovar 9 and acetylated-GPL-9
Proposed Epitope4-O-acetyl-2,3-di-O-methyl-α-L-fucopyranosyl-(1-->4)-β-D-glucuronopyranosyl residues seemed to be the part of the epitope
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used for the identification and classification of M. avium isolates. This Mab can be applied directly to bacterial cultures, thus allowing easy, rapid identification of at least half of the M. avium isolates encountered in the clinical laboratory
Curator IDAA + AS
Date of Curation04-10-2010
ReferencesPMC260783

Record - 14 of 32   [TOP]

PolysacDB ID1676
Carbohydrate NameGlycopeptidolipid antigen   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium avium complex serovar 9   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThis antigen is composed of a glycosylated lipopeptide core, fatty acyl-D-phenylalanine-D-allothreonine-D-alanine-L-alaninyl-O-(3,4-di-O-methyl-α-L-rhamnopyranoside), to which a haptenic oligosaccharide is linked at the threonine substituent
BCSDB Structure133663
Proposed FunctionThis oligosaccharide unit is the source of the dominant immunogenicity of members of the M. avium complex, i.e., their characteristic agglutinability and type specificity
Antigenic NatureWhole washed heat-killed bacteria
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 5510
Antibody Type ClassIgG3
Assay SystemELISA, Inhibition assays, dot blot
Cross ReactivityThis antibody cross-reacted with Whole cells of serovar 9 and acetylated-GPL-9
Proposed Epitope4-O-acetyl-2,3-di-O-methyl-α-L-fucopyranosyl-(1-->4)-β-D-glucuronopyranosyl residues seemed to be the part of the epitope
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used for the identification and classification of M. avium isolates. This Mab can be applied directly to bacterial cultures, thus allowing easy, rapid identification of at least half of the M. avium isolates encountered in the clinical laboratory
Curator IDAA + AS
Date of Curation04-10-2010
ReferencesPMC260783

Record - 15 of 32   [TOP]

PolysacDB ID1677
Carbohydrate NameGlycopeptidolipid antigen   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium avium complex serovar 9   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThis antigen is composed of a glycosylated lipopeptide core, fatty acyl-D-phenylalanine-D-allothreonine-D-alanine-L-alaninyl-O-(3,4-di-O-methyl-α-L-rhamnopyranoside), to which a haptenic oligosaccharide is linked at the threonine substituent
BCSDB Structure133663
Proposed FunctionThis oligosaccharide unit is the source of the dominant immunogenicity of members of the M. avium complex, i.e., their characteristic agglutinability and type specificity
Antigenic NatureWhole washed heat-killed bacteria
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 2647
Antibody Type ClassIgG3
Assay SystemELISA, Inhibition assays, dot blot
Cross ReactivityThis antibody cross-reacted with Whole cells of serovar 9 and acetylated-GPL-9
Proposed Epitope4-O-acetyl-2,3-di-O-methyl-α-L-fucopyranosyl-(1-->4)-β-D-glucuronopyranosyl residues seemed to be the part of the epitope
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used for the identification and classification of M. avium isolates. This Mab can be applied directly to bacterial cultures, thus allowing easy, rapid identification of at least half of the M. avium isolates encountered in the clinical laboratory
Curator IDAA + AS
Date of Curation04-10-2010
ReferencesPMC260783

Record - 16 of 32   [TOP]

PolysacDB ID1678
Carbohydrate NameGlycopeptidolipid antigen   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium avium complex serovar 9   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThis antigen is composed of a glycosylated lipopeptide core, fatty acyl-D-phenylalanine-D-allothreonine-D-alanine-L-alaninyl-O-(3,4-di-O-methyl-α-L-rhamnopyranoside), to which a haptenic oligosaccharide is linked at the threonine substituent
BCSDB Structure133663
Proposed FunctionThis oligosaccharide unit is the source of the dominant immunogenicity of members of the M. avium complex, i.e., their characteristic agglutinability and type specificity
Antigenic NatureWhole washed heat-killed bacteria
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 2643
Antibody Type ClassIgG3
Assay SystemELISA, Inhibition assays, dot blot
Cross ReactivityThis antibody cross-reacted with Whole cells of serovar 9 and acetylated-GPL-9
Proposed Epitope4-O-acetyl-2,3-di-O-methyl-α-L-fucopyranosyl-(1-->4)-β-D-glucuronopyranosyl residues seemed to be the part of the epitope
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used for the identification and classification of M. avium isolates. This Mab can be applied directly to bacterial cultures, thus allowing easy, rapid identification of at least half of the M. avium isolates encountered in the clinical laboratory
Curator IDAA + AS
Date of Curation04-10-2010
ReferencesPMC260783

Record - 17 of 32   [TOP]

PolysacDB ID1679
Carbohydrate NameGlycopeptidolipid antigen   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium avium complex serovar 9   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThis antigen is composed of a glycosylated lipopeptide core, fatty acyl-D-phenylalanine-D-allothreonine-D-alanine-L-alaninyl-O-(3,4-di-O-methyl-α-L-rhamnopyranoside), to which a haptenic oligosaccharide is linked at the threonine substituent
BCSDB Structure133663
Proposed FunctionThis oligosaccharide unit is the source of the dominant immunogenicity of members of the M. avium complex, i.e., their characteristic agglutinability and type specificity
Antigenic NatureWhole washed heat-killed bacteria
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 2675
Antibody Type ClassIgG3
Assay SystemELISA, Inhibition assays, dot blot
Cross ReactivityThis antibody cross-reacted with Whole cells of serovar 9 and acetylated-GPL-9
Proposed Epitope4-O-acetyl-2,3-di-O-methyl-α-L-fucopyranosyl-(1-->4)-β-D-glucuronopyranosyl residues seemed to be the part of the epitope
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used for the identification and classification of M. avium isolates. This Mab can be applied directly to bacterial cultures, thus allowing easy, rapid identification of at least half of the M. avium isolates encountered in the clinical laboratory
Curator IDAA + AS
Date of Curation05-10-2010
ReferencesPMC260783

Record - 18 of 32   [TOP]

PolysacDB ID1680
Carbohydrate NameGlycopeptidolipid antigen   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium avium complex serovar 9   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThis antigen is composed of a glycosylated lipopeptide core, fatty acyl-D-phenylalanine-D-allothreonine-D-alanine-L-alaninyl-O-(3,4-di-O-methyl-α-L-rhamnopyranoside), to which a haptenic oligosaccharide is linked at the threonine substituent
BCSDB Structure133663
Proposed FunctionThis oligosaccharide unit is the source of the dominant immunogenicity of members of the M. avium complex, i.e., their characteristic agglutinability and type specificity
Antigenic NatureWhole washed heat-killed bacteria
Carrier NameNil
Conjugate MethodNil
AntibodiesMab B192
Antibody Type ClassIgG2b
Assay SystemELISA, Inhibition assays, dot blot
Cross ReactivityThis antibody cross-reacted with Whole cells of serovar 9 and acetylated-GPL-9 and it was highly cross-reactive for other serovars and their GPLs
Proposed Epitope4-O-acetyl-2,3-di-O-methyl-α-L-fucopyranosyl-(1-->4)-β-D-glucuronopyranosyl residues seemed to be the part of the epitope
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used for the identification and classification of M. avium isolates. This Mab can be applied directly to bacterial cultures, thus allowing easy, rapid identification of at least half of the M. avium isolates encountered in the clinical laboratory
Curator IDAA + AS
Date of Curation05-10-2010
ReferencesPMC260783

Record - 19 of 32   [TOP]

PolysacDB ID1681
Carbohydrate NameGlycopeptidolipid antigen   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium avium complex serovar 9   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThis antigen is composed of a glycosylated lipopeptide core, fatty acyl-D-phenylalanine-D-allothreonine-D-alanine-L-alaninyl-O-(3,4-di-O-methyl-α-L-rhamnopyranoside), to which a haptenic oligosaccharide is linked at the threonine substituent
BCSDB Structure133663
Proposed FunctionThis oligosaccharide unit is the source of the dominant immunogenicity of members of the M. avium complex, i.e., their characteristic agglutinability and type specificity
Antigenic NatureWhole washed heat-killed bacteria
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 154
Antibody Type ClassIgG2b
Assay SystemELISA, Inhibition assays, dot blot
Cross ReactivityThis antibody cross-reacted with Whole cells of serovar 9 and acetylated-GPL-9 and it was highly cross-reactive for other serovars and their GPLs
Proposed Epitope4-O-acetyl-2,3-di-O-methyl-α-L-fucopyranosyl-(1-->4)-β-D-glucuronopyranosyl residues seemed to be the part of the epitope
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used for the identification and classification of M. avium isolates. This Mab can be applied directly to bacterial cultures, thus allowing easy, rapid identification of at least half of the M. avium isolates encountered in the clinical laboratory
Curator IDAA + AS
Date of Curation05-10-2010
ReferencesPMC260783

Record - 20 of 32   [TOP]

PolysacDB ID1682
Carbohydrate NameGlycopeptidolipid antigen   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium avium complex serovar 9   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThis antigen is composed of a glycosylated lipopeptide core, fatty acyl-D-phenylalanine-D-allothreonine-D-alanine-L-alaninyl-O-(3,4-di-O-methyl-α-L-rhamnopyranoside), to which a haptenic oligosaccharide is linked at the threonine substituent
BCSDB Structure133663
Proposed FunctionThis oligosaccharide unit is the source of the dominant immunogenicity of members of the M. avium complex, i.e., their characteristic agglutinability and type specificity
Antigenic NatureWhole washed heat-killed bacteria
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 1173
Antibody Type ClassIgM
Assay SystemELISA, Inhibition assays, dot blot
Cross ReactivityThis antibody cross-reacted with Whole cells of serovar 9 and acetylated-GPL-9 and it was highly cross-reactive for other serovars and their GPLs
Proposed Epitope4-O-acetyl-2,3-di-O-methyl-α-L-fucopyranosyl-(1-->4)-β-D-glucuronopyranosyl residues seemed to be the part of the epitope
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used for the identification and classification of M. avium isolates. This Mab can be applied directly to bacterial cultures, thus allowing easy, rapid identification of at least half of the M. avium isolates encountered in the clinical laboratory
Curator IDAA + AS
Date of Curation05-10-2010
ReferencesPMC260783

Record - 21 of 32   [TOP]

PolysacDB ID1683
Carbohydrate NameGlycopeptidolipid antigen   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium avium complex serovar 9   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThis antigen is composed of a glycosylated lipopeptide core, fatty acyl-D-phenylalanine-D-allothreonine-D-alanine-L-alaninyl-O-(3,4-di-O-methyl-α-L-rhamnopyranoside), to which a haptenic oligosaccharide is linked at the threonine substituent
BCSDB Structure133663
Proposed FunctionThis oligosaccharide unit is the source of the dominant immunogenicity of members of the M. avium complex, i.e., their characteristic agglutinability and type specificity
Antigenic NatureWhole washed heat-killed bacteria
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 1175
Antibody Type ClassIgM
Assay SystemELISA, Inhibition assays, dot blot
Cross ReactivityThis antibody cross-reacted with Whole cells of serovar 9 and acetylated-GPL-9 and it was highly cross-reactive for other serovars and their GPLs
Proposed Epitope4-O-acetyl-2,3-di-O-methyl-α-L-fucopyranosyl-(1-->4)-β-D-glucuronopyranosyl residues seemed to be the part of the epitope
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used for the identification and classification of M. avium isolates. This Mab can be applied directly to bacterial cultures, thus allowing easy, rapid identification of at least half of the M. avium isolates encountered in the clinical laboratory
Curator IDAA + AS
Date of Curation05-10-2010
ReferencesPMC260783

Record - 22 of 32   [TOP]

PolysacDB ID1684
Carbohydrate NameGlycopeptidolipid antigen   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium avium complex serovar 9   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThis antigen is composed of a glycosylated lipopeptide core, fatty acyl-D-phenylalanine-D-allothreonine-D-alanine-L-alaninyl-O-(3,4-di-O-methyl-α-L-rhamnopyranoside), to which a haptenic oligosaccharide is linked at the threonine substituent
BCSDB Structure133663
Proposed FunctionThis oligosaccharide unit is the source of the dominant immunogenicity of members of the M. avium complex, i.e., their characteristic agglutinability and type specificity
Antigenic NatureWhole washed heat-killed bacteria
Carrier NameNil
Conjugate MethodNil
AntibodiesMab R124
Antibody Type ClassIgM
Assay SystemELISA, Inhibition assays, dot blot
Cross ReactivityThis antibody cross-reacted with Whole cells of serovar 9 and acetylated-GPL-9 and it was highly cross-reactive for other serovars and their GPLs
Proposed Epitope4-O-acetyl-2,3-di-O-methyl-α-L-fucopyranosyl-(1-->4)-β-D-glucuronopyranosyl residues seemed to be the part of the epitope
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used for the identification and classification of M. avium isolates. This Mab can be applied directly to bacterial cultures, thus allowing easy, rapid identification of at least half of the M. avium isolates encountered in the clinical laboratory
Curator IDAA + AS
Date of Curation06-10-2010
ReferencesPMC260783

Record - 23 of 32   [TOP]

PolysacDB ID1685
Carbohydrate NameGlycopeptidolipid antigen   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium avium complex serovar 9   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThis antigen is composed of a glycosylated lipopeptide core, fatty acyl-D-phenylalanine-D-allothreonine-D-alanine-L-alaninyl-O-(3,4-di-O-methyl-α-L-rhamnopyranoside), to which a haptenic oligosaccharide is linked at the threonine substituent
BCSDB Structure133663
Proposed FunctionThis oligosaccharide unit is the source of the dominant immunogenicity of members of the M. avium complex, i.e., their characteristic agglutinability and type specificity
Antigenic NatureWhole washed heat-killed bacteria
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 7534
Antibody Type ClassIgM
Assay SystemELISA, Inhibition assays, dot blot
Cross ReactivityThis antibody cross-reacted with Whole cells of serovar 9 and acetylated-GPL-9 and it was highly cross-reactive for other serovars and their GPLs
Proposed Epitope4-O-acetyl-2,3-di-O-methyl-α-L-fucopyranosyl-(1-->4)-β-D-glucuronopyranosyl residues seemed to be the part of the epitope
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used for the identification and classification of M. avium isolates. This Mab can be applied directly to bacterial cultures, thus allowing easy, rapid identification of at least half of the M. avium isolates encountered in the clinical laboratory
Curator IDAA + AS
Date of Curation06-10-2010
ReferencesPMC260783

Record - 24 of 32   [TOP]

PolysacDB ID1686
Carbohydrate NameGlycopeptidolipid antigen   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium avium complex serovar 9   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThis antigen is composed of a glycosylated lipopeptide core, fatty acyl-D-phenylalanine-D-allothreonine-D-alanine-L-alaninyl-O-(3,4-di-O-methyl-α-L-rhamnopyranoside), to which a haptenic oligosaccharide is linked at the threonine substituent
BCSDB Structure133663
Proposed FunctionThis oligosaccharide unit is the source of the dominant immunogenicity of members of the M. avium complex, i.e., their characteristic agglutinability and type specificity
Antigenic NatureWhole washed heat-killed bacteria
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 4102
Antibody Type ClassIgM
Assay SystemELISA, Inhibition assays, dot blot
Cross ReactivityThis antibody cross-reacted with Whole cells of serovar 9 and acetylated-GPL-9 and it was highly cross-reactive for other serovars and their GPLs
Proposed Epitope4-O-acetyl-2,3-di-O-methyl-α-L-fucopyranosyl-(1-->4)-β-D-glucuronopyranosyl residues seemed to be the part of the epitope
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used for the identification and classification of M. avium isolates. This Mab can be applied directly to bacterial cultures, thus allowing easy, rapid identification of at least half of the M. avium isolates encountered in the clinical laboratory
Curator IDAA + AS
Date of Curation06-10-2010
ReferencesPMC260783

Record - 25 of 32   [TOP]

PolysacDB ID1687
Carbohydrate NameGlycopeptidolipid antigen   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium avium complex serovar 9   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThis antigen is composed of a glycosylated lipopeptide core, fatty acyl-D-phenylalanine-D-allothreonine-D-alanine-L-alaninyl-O-(3,4-di-O-methyl-α-L-rhamnopyranoside), to which a haptenic oligosaccharide is linked at the threonine substituent
BCSDB Structure133663
Proposed FunctionThis oligosaccharide unit is the source of the dominant immunogenicity of members of the M. avium complex, i.e., their characteristic agglutinability and type specificity
Antigenic NatureWhole washed heat-killed bacteria
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 4189
Antibody Type ClassIgM
Assay SystemELISA, Inhibition assays, dot blot
Cross ReactivityThis antibody cross-reacted with Whole cells of serovar 9 and acetylated-GPL-9 and it was highly cross-reactive for other serovars and their GPLs
Proposed Epitope4-O-acetyl-2,3-di-O-methyl-α-L-fucopyranosyl-(1-->4)-β-D-glucuronopyranosyl residues seemed to be the part of the epitope
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used for the identification and classification of M. avium isolates. This Mab can be applied directly to bacterial cultures, thus allowing easy, rapid identification of at least half of the M. avium isolates encountered in the clinical laboratory
Curator IDAA + AS
Date of Curation06-10-2010
ReferencesPMC260783

Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036