PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
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PolysacDB ID1479
Carbohydrate NameLex carbohydrate   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
Microbe NameHelicobacter pylori   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe structure consists of the following residues : (Galβ1-->4[Fucα1-->3]GlcNAc
BCSDB Structure10702
Proposed FunctionN/A
Antigenic NatureN/A
Carrier NameN/A
Conjugate MethodN/A
AntibodiesMab 85-5000
Antibody Type ClassIgM
Assay SystemImmunoblotting, immunoelectron microscopy and ELISA
Cross ReactivityThis Lex specific Mab cross-reacted with H. pylori strains NCTC11637, UA799, UA802, UA825, UA861, UA1182, and UA1206
Proposed EpitopeGalβ1-->4[Fucα1-->3]GlcNAc
IEDB Epitope76711
Proposed UtilityN/A
Curator IDAA + AS
Date of Curation30-07-2010
ReferencesPMC173655

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PolysacDB ID1480
Carbohydrate NameLex carbohydrate   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
Microbe NameHelicobacter pylori   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureN/A
Carrier NameN/A
Conjugate MethodN/A
AntibodiesMab CNM 1336
Antibody Type ClassIgM
Assay SystemImmunoblotting, immunoelectron microscopy and ELISA
Cross ReactivityThis Lex specific Mab cross-reacted with H. pylori strains NCTC11637, UA799, UA802, UA825, UA861, UA1182, and UA1206
Proposed EpitopeGalβ1-->4[Fucα1-->3]GlcNAcβ1-->3Galβ1-->4Glc
IEDB Epitope76711
Proposed UtilityN/A
Curator IDAA + AS
Date of Curation30-07-2010
ReferencesPMC173655

Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036