PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
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PolysacDB ID2613
Carbohydrate NameLipoarabinomannan like polysaccharides   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium paratuberculosis   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureWhole cell extract
Carrier NameNil
Conjugate MethodNil
AntibodiesMab PII-B1
Antibody Type ClassIgM
Assay SystemELISA, ConA lectin Affinity Chromatography
Cross ReactivityThis antibody was cross-reactive to M, tuberculosis, M. kansasii, M.avium
Proposed EpitopeN/A
IEDB EpitopeN/A
Proposed UtilityUsing this antibody it was for the first time proposed that LaM like poysaccharides were released into the growth medium during mycobacterial growth.
Curator IDAA + AS
Date of Curation19-07-2011
ReferencesPMC174607

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PolysacDB ID2614
Carbohydrate NameLipoarabinomannan like polysaccharides   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium paratuberculosis   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureWhole cell extract
Carrier NameNil
Conjugate MethodNil
AntibodiesMab PII-D5
Antibody Type ClassIgG2b
Assay SystemELISA, ConA lectin Affinity Chromatography
Cross ReactivityThis antibody was cross-reactive to M, tuberculosis, M. kansasii, M.avium
Proposed EpitopeN/A
IEDB EpitopeN/A
Proposed UtilityUsing this antibody it was for the first time proposed that LaM like poysaccharides were released into the growth medium during mycobacterial growth
Curator IDAA + AS
Date of Curation20-07-2011
ReferencesPMC174607

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PolysacDB ID2615
Carbohydrate NameLipoarabinomannan like polysaccharides   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium paratuberculosis   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureWhole cell extract
Carrier NameNil
Conjugate MethodNil
AntibodiesMab PII-D1
Antibody Type ClassIgG3
Assay SystemELISA, ConA lectin Affinity Chromatography
Cross ReactivityThis antibody was cross-reactive to M, tuberculosis, M. kansasii, M.avium
Proposed EpitopeN/A
IEDB EpitopeN/A
Proposed UtilityUsing this antibody it was for the first time proposed that LaM like poysaccharides were released into the growth medium during mycobacterial growth
Curator IDAA + AS
Date of Curation20-07-2011
ReferencesPMC174607

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PolysacDB ID2616
Carbohydrate NameLipoarabinomannan like polysaccharides   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium paratuberculosis   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureWhole cell extract
Carrier NameNil
Conjugate MethodNil
AntibodiesMab PII-C3
Antibody Type ClassIgG3
Assay SystemELISA, ConA lectin Affinity Chromatography
Cross ReactivityThis antibody was cross-reactive to M, tuberculosis, M. kansasii, M.avium
Proposed EpitopeN/A
IEDB EpitopeN/A
Proposed UtilityUsing this antibody it was for the first time proposed that LaM like poysaccharides were released into the growth medium during mycobacterial growth
Curator IDAA + AS
Date of Curation21-07-2011
ReferencesPMC174607

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