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PolysacDB ID | 1547 |
Carbohydrate Name | Lipophosphoglycan (Drugpedia) |
Carbohydrate Class | Glycolipid |
Microbe Name | Leishmania mexicana (NCBI Taxonomy) (Drugpedia) |
Basic Structure | LPG contains [PO4-->6Gal(β1-->4)Man(α1)] phosphosaccharide repeats linked to a conserved phosphosaccharide core and a conserved lyso alkylphosphatidylinositol residue. In contrast to L. donovani LPG, which exclusively contains the phosphodisaccharide repeats |
BCSDB Structure | 2568 |
Proposed Function | N/A |
Antigenic Nature | Concanavalin A (ConA)-binding membrane components from L. mexicana |
Carrier Name | Nil |
Conjugate Method | Nil |
Antibodies | Mab L7.25 |
Antibody Type Class | IgM |
Assay System | ELISA, immunoblotting |
Cross Reactivity | This Mab cross-reacted with a highly glycosylated protein - acid phosphatase |
Proposed Epitope | The epitope was proposed to consist of phosphosaccharide repeats or the sugar residues forming the cap at the non-reducing end |
IEDB Epitope | 76720 |
Proposed Utility | The epitopes recognized by this Mab have been localized in promastigotes and infected macrophages |
Curator ID | AA + AS |
Date of Curation | 03-09-2010 |
References | 1721919 |
PolysacDB ID | 1548 |
Carbohydrate Name | Lipophosphoglycan (Drugpedia) |
Carbohydrate Class | Glycolipid |
Microbe Name | Leishmania mexicana (NCBI Taxonomy) (Drugpedia) |
Basic Structure | LPG contains [PO4-->6Gal(β1-->4)Man(α1)] phosphosaccharide repeats linked to a conserved phosphosaccharide core and a conserved lyso alkylphosphatidylinositol residue. In contrast to L. donovani LPG, which exclusively contains the phosphodisaccharide repeats |
BCSDB Structure | 2568 |
Proposed Function | N/A |
Antigenic Nature | Con A binding proteins |
Carrier Name | Nil |
Conjugate Method | Nil |
Antibodies | Mab AP3 |
Antibody Type Class | IgG1 |
Assay System | ELISA, immunoblotting |
Cross Reactivity | This Mab cross-reacted with a highly glycosylated protein - acid phosphatase |
Proposed Epitope | The epitope was proposed to consist of phosphosaccharide repeats or the sugar residues forming the cap at the non-reducing end |
IEDB Epitope | 76720 |
Proposed Utility | The epitopes recognized by this Mab have been localized in promastigotes and infected macrophages |
Curator ID | AA + AS |
Date of Curation | 04-09-2010 |
References | 1721919 |
Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036 |