PolysacDB ID | 1511 |
Carbohydrate Name | Lipopolysaccharide and capsular polysaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe Name | Actinobacillus pleuropneumoniae serotype b strains 81-750 and B78-3760 (NCBI Taxonomy) (Drugpedia) |
Basic Structure | O-polysaccharide structure of strain 81-750 is a linear unbranched homopolymer of 1,6-linked-D-galactopyranosyl residues. |
BCSDB Structure | N/A |
Proposed Function | LPS is an important virulence factor. It molecule plays an important role in adherence of the bacterium to porcine respiratory tract cells and mucus |
Antigenic Nature | Formaldehyde killed cells of strains 81-750 and B78-3760 and LPS coated whole cells of strain 81-750. |
Carrier Name | Nil |
Conjugate Method | Nil |
Antibodies | Mab 3A5 |
Antibody Type Class | IgG1 |
Assay System | ELISA and dot ELISA |
Cross Reactivity | This antibody cross-reacted strongly with CPS of serotype 5b |
Proposed Epitope | N/A |
IEDB Epitope | N/A |
Proposed Utility | This Mab can be used to detect the presence of bacterial antigens in lungs from infected animals |
Curator ID | AA + AS |
Date of Curation | 08-08-2010
|
References | PMC1263782 |