PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
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PolysacDB ID1008
Carbohydrate NameMycolyl-arabinogalactan-peptidoglycan complex   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameMycobacterium tuberculosis   (NCBI Taxonomy)   (Drugpedia)
Basic StructureMycolyl-arabinogalactan-peptidoglycan complex is the fraction of the mycobacterial cell wall left after removing all soluble carbohydrates, proteins and lipids
BCSDB StructureN/A
Proposed FunctionContains lipoarabinomannan as well as arabinose that are important virulence factors
Antigenic NatureHeat killed Mycobacterium tuberculosis
Carrier NameNil
Conjugate MethodNil
AntibodiesMabs 4f11
Antibody Type ClassIgM
Assay SystemIndirect immunofluorescence, ELISA, western blotting
Cross ReactivityThis antibody cross-reacted with large number of mycobacterial species.
Proposed EpitopeArabinose moiety of Lipoarabinomannan
IEDB EpitopeN/A
Proposed UtilityThis antibody has been used in the detection of mycobacteria in clinical samples
Curator IDAA + AS
Date of Curation02-01-2010
ReferencesPMC229406

Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036