| PolysacDB ID | 2212 |
| Carbohydrate Name | O-polysaccharide 9 (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe Name | Salmonella typhi (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | LPS O-antigens are formed by the polymerization of a tetrasaccharide repeating unit which is composed of [tyvelose-α[1-->3]-D-mannose-α[1-->3]-L-rhamnose-α[1-->3]-Dα[1-->2]
|
| BCSDB Structure | N/A |
| Proposed Function | It is an important virulence factor. It modulates the host immune defense mechanisms by interference with the normal serum bactericidal activity and/or the process of phagocytosis |
| Antigenic Nature | Heat killed bacteria and purified Vi polysaccharide |
| Carrier Name | Nil |
| Conjugate Method | Nil |
| Antibodies | Mab MATy-O9 |
| Antibody Type Class | IgG3 |
| Assay System | N/A |
| Cross Reactivity | This Mab cross-reacted with O9 containing dodecasaccharide glycoconjugate which was derived from S. enteritidis SH1262 |
| Proposed Epitope | The dideoxyhexosyl tyvelose residue is the immunodominant epitope |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab was shown to be a useful serotyping agent by correct identification in slide agglutination tests of 32 clinical isolates of all the S. typhi and other serogroup D salmonellae among a total of 140 bacterial isolates representing eight different Enterobacteriaceae genera tested |
| Curator ID | AA + AS |
| Date of Curation | 05-03-2011
|
| References | 1426999 |