PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613

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PolysacDB ID	1337
Carbohydrate Name	Phosphopeptidomannan (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Candida albicans (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed Function	N/A
Antigenic Nature	Whole cells
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab EB-CA1
Antibody Type Class	N/A
Assay System	ELISA, immunoblotting
Cross Reactivity	N/A
Proposed Epitope	The probable epitope consists of 1 to more than 11 mannosyl residues and linked mainly through α(1-->2) and α(1-->3) bonds
IEDB Epitope	N/A
Proposed Utility	This Mab helped in epitope elucidation of the mannans present on Candidial surfaces
Curator ID	AA + AS
Date of Curation	19-06-2010
References	PMC257398

Record - 2 of 6 [TOP]

PolysacDB ID	1338
Carbohydrate Name	Phosphopeptidomannan (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Candida albicans (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed Function	N/A
Antigenic Nature	Whole cells
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab EB-CA2
Antibody Type Class	N/A
Assay System	ELISA, immunoblotting
Cross Reactivity	N/A
Proposed Epitope	The probable epitope consists of 1 to more than 11 mannosyl residues and linked mainly through α(1-->2) and α(1-->3) bonds
IEDB Epitope	N/A
Proposed Utility	This Mab helped in epitope elucidation of the mannans present on Candidial surfaces
Curator ID	AA + AS
Date of Curation	19-06-2010
References	PMC257398

Record - 3 of 6 [TOP]

PolysacDB ID	1339
Carbohydrate Name	Phosphopeptidomannan (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Candida albicans (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed Function	N/A
Antigenic Nature	Whole cells
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab H5
Antibody Type Class	N/A
Assay System	ELISA, immunoblotting
Cross Reactivity	N/A
Proposed Epitope	The probable epitope consists of 1 to more than 11 mannosyl residues and linked mainly through α(1-->2) and α(1-->3) bonds
IEDB Epitope	N/A
Proposed Utility	This Mab helped in epitope elucidation of the mannans present on Candidial surfaces
Curator ID	AA + AS
Date of Curation	19-06-2010
References	PMC257398

Record - 4 of 6 [TOP]

PolysacDB ID	1340
Carbohydrate Name	Phosphopeptidomannan (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Candida albicans (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed Function	N/A
Antigenic Nature	Whole cells
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab AF1
Antibody Type Class	N/A
Assay System	ELISA, immunoblotting
Cross Reactivity	N/A
Proposed Epitope	The epitope consiosts of mannosyl residues from mannobiose to mannoheptaose are bound through β(1-->2) linkage
IEDB Epitope	N/A
Proposed Utility	This Mab helped in epitope elucidation of the mannans present on Candidial surfaces
Curator ID	AA + AS
Date of Curation	22-06-2010
References	PMC257398

Record - 5 of 6 [TOP]

PolysacDB ID	1341
Carbohydrate Name	Phosphopeptidomannan (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Candida albicans (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed Function	N/A
Antigenic Nature	Whole cells
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab C6
Antibody Type Class	N/A
Assay System	ELISA, immunoblotting
Cross Reactivity	N/A
Proposed Epitope	The epitope consiosts of mannosyl residues from mannobiose to mannoheptaose are bound through β(1-->2) linkage
IEDB Epitope	N/A
Proposed Utility	This Mab helped in epitope elucidation of the mannans present on Candidial surfaces
Curator ID	AA + AS
Date of Curation	22-06-2010
References	PMC257398

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PolysacDB ID	1342
Carbohydrate Name	Phosphopeptidomannan (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe Name	Candida albicans (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed Function	N/A
Antigenic Nature	Whole cells
Carrier Name	Nil
Conjugate Method	Nil
Antibodies	Mab 5B2
Antibody Type Class	N/A
Assay System	ELISA, immunoblotting
Cross Reactivity	N/A
Proposed Epitope	The epitope consists of mannopyranosyl units bound through β(1-->2) linkages present both within the oligomannoside H pool and at the nonreducing end of some oligomannosides A
IEDB Epitope	N/A
Proposed Utility	This Mab helped in epitope elucidation of the mannans present on Candidial surfaces
Curator ID	AA + AS
Date of Curation	23-06-2010
References	PMC257398

Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036