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PolysacDB ID | 2647 |
Carbohydrate Name | Serotype b-specific polysaccharide antigen (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe Name | Actinobacillus actinomycetemcomitans Y4 (NCBI Taxonomy) (Drugpedia) |
Basic Structure | Serotype b-specific antigen of A. actinomycetemcomitans is a capsular polysaccharide-like antigen consisting of a disaccharide repeating unit, 33)-a-D-fucopyranosyl-(132)-b-L-rhamnopyranosyl-(1- |
BCSDB Structure | N/A |
Proposed Function | SPA of A. actinomycetemcomitans plays an important role in the resistance to phagocytosis and killing by human PMNs. |
Antigenic Nature | Whole cells |
Carrier Name | N/A |
Conjugate Method | N/A |
Antibodies | IgG1 |
Antibody Type Class | Mab S2 |
Assay System | Chemiluminescence (CL) assay, immunoblotting and phagocytic killing assay |
Cross Reactivity | N/A |
Proposed Epitope | N/A |
IEDB Epitope | N/A |
Proposed Utility | This Mab enhanced CL responses of human PMNs to the organism and killing of the organism by human PMNs |
Curator ID | AA + AS |
Date of Curation | 21-01-2012 |
References | PMC173659 |
PolysacDB ID | 2648 |
Carbohydrate Name | Serotype b-specific polysaccharide antigen (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe Name | Actinobacillus actinomycetemcomitans Y4 (NCBI Taxonomy) (Drugpedia) |
Basic Structure | Serotype b-specific antigen of A. actinomycetemcomitans is a capsular polysaccharide-like antigen consisting of a disaccharide repeating unit, 33)-a-D-fucopyranosyl-(132)-b-L-rhamnopyranosyl-(1- |
BCSDB Structure | N/A |
Proposed Function | SPA of A. actinomycetemcomitans plays an important role in the resistance to phagocytosis and killing by human PMNs. |
Antigenic Nature | Whole cells |
Carrier Name | N/A |
Conjugate Method | N/A |
Antibodies | IgG2a |
Antibody Type Class | Mab S4 |
Assay System | Chemiluminescence (CL) assay, immunoblotting and phagocytic killing assay |
Cross Reactivity | N/A |
Proposed Epitope | N/A |
IEDB Epitope | N/A |
Proposed Utility | This Mab enhanced CL responses of human PMNs to the organism and killing of the organism by human PMNs |
Curator ID | AA + AS |
Date of Curation | 21-01-2012 |
References | PMC173659 |
PolysacDB ID | 2649 |
Carbohydrate Name | Serotype b-specific polysaccharide antigen (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe Name | Actinobacillus actinomycetemcomitans Y4 (NCBI Taxonomy) (Drugpedia) |
Basic Structure | Serotype b-specific antigen of A. actinomycetemcomitans is a capsular polysaccharide-like antigen consisting of a disaccharide repeating unit, 33)-a-D-fucopyranosyl-(132)-b-L-rhamnopyranosyl-(1- |
BCSDB Structure | N/A |
Proposed Function | SPA of A. actinomycetemcomitans plays an important role in the resistance to phagocytosis and killing by human PMNs. |
Antigenic Nature | Whole cells |
Carrier Name | N/A |
Conjugate Method | N/A |
Antibodies | IgG3 |
Antibody Type Class | Mab S5 |
Assay System | Chemiluminescence (CL) assay, immunoblotting and phagocytic killing assay |
Cross Reactivity | N/A |
Proposed Epitope | N/A |
IEDB Epitope | N/A |
Proposed Utility | This Mab enhanced CL responses of human PMNs to the organism and killing of the organism by human PMNs |
Curator ID | AA + AS |
Date of Curation | 25-01-2012 |
References | PMC173659 |
PolysacDB ID | 2650 |
Carbohydrate Name | Serotype b-specific polysaccharide antigen (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe Name | Actinobacillus actinomycetemcomitans Y4 (NCBI Taxonomy) (Drugpedia) |
Basic Structure | Serotype b-specific antigen of A. actinomycetemcomitans is a capsular polysaccharide-like antigen consisting of a disaccharide repeating unit, 33)-a-D-fucopyranosyl-(132)-b-L-rhamnopyranosyl-(1- |
BCSDB Structure | N/A |
Proposed Function | SPA of A. actinomycetemcomitans plays an important role in the resistance to phagocytosis and killing by human PMNs. |
Antigenic Nature | Whole cells |
Carrier Name | N/A |
Conjugate Method | N/A |
Antibodies | IgG3 |
Antibody Type Class | Mab S8 |
Assay System | Chemiluminescence (CL) assay, immunoblotting and phagocytic killing assay |
Cross Reactivity | N/A |
Proposed Epitope | N/A |
IEDB Epitope | N/A |
Proposed Utility | This Mab enhanced CL responses of human PMNs to the organism and killing of the organism by human PMNs |
Curator ID | AA + AS |
Date of Curation | 25-01-2012 |
References | PMC173659 |
PolysacDB ID | 2651 |
Carbohydrate Name | Serotype b-specific polysaccharide antigen (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe Name | Actinobacillus actinomycetemcomitans Y4 (NCBI Taxonomy) (Drugpedia) |
Basic Structure | Serotype b-specific antigen of A. actinomycetemcomitans is a capsular polysaccharide-like antigen consisting of a disaccharide repeating unit, 33)-a-D-fucopyranosyl-(132)-b-L-rhamnopyranosyl-(1- |
BCSDB Structure | N/A |
Proposed Function | SPA of A. actinomycetemcomitans plays an important role in the resistance to phagocytosis and killing by human PMNs. |
Antigenic Nature | Whole cells |
Carrier Name | N/A |
Conjugate Method | N/A |
Antibodies | IgM |
Antibody Type Class | Mab S9 |
Assay System | Chemiluminescence (CL) assay, immunoblotting and phagocytic killing assay |
Cross Reactivity | N/A |
Proposed Epitope | N/A |
IEDB Epitope | N/A |
Proposed Utility | This Mab did not enhance CL responses of human PMNs to the organism and did not promote killing of the organism by human PMNs |
Curator ID | AA + AS |
Date of Curation | 25-01-2012 |
References | PMC173659 |
Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036 |