PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
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PolysacDB ID2427
Carbohydrate NameStreptococcus pneumoniae type XIV polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
Microbe NameStreptococcus pneumoniae type XIV   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureHeat killed cells
Carrier NameNil
Conjugate MethodNil
AntibodiesMab B2
Antibody Type ClassIgM
Assay SystemHemagglutination, ELISA, Cryoprecipitation and cryoprecipitation-inhibition assays
Cross ReactivityThis Mab cross-reacted with rabbit and human erythrocytes at temperatures below 37°C. This Mab also reacted with phenylLac-BGG
Proposed EpitopeThis Mab was specific for N-acetyl-lactosamine, the immunodominant sugar residue expressed on type XIV polysaccharide
IEDB EpitopeN/A
Proposed UtilityThis Mab precipitated at low temperatures and also reacted with rabbit and human erythrocytes at low temperature
Curator IDAA + AS
Date of Curation10-05-2011
References3989304

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PolysacDB ID2428
Carbohydrate NameStreptococcus pneumoniae type XIV polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
Microbe NameStreptococcus pneumoniae type XIV   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureHeat killed cells
Carrier NameNil
Conjugate MethodNil
AntibodiesMab F5
Antibody Type ClassIgM
Assay SystemHemagglutination, ELISA, Cryoprecipitation and cryoprecipitation-inhibition assays
Cross ReactivityThis Mab cross-reacted with rabbit erythrocytes at temperatures below 37°C, but did not react with phenylLac-BGG
Proposed EpitopeThis Mab was specific for N-acetyl-lactosamine, the immunodominant sugar residue expressed on type XIV polysaccharide
IEDB EpitopeN/A
Proposed UtilityThis Mab precipitated at low temperatures and also reacted with rabbit erythrocytes at low temperature
Curator IDAA + AS
Date of Curation11-05-2011
References3989304

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PolysacDB ID2429
Carbohydrate NameStreptococcus pneumoniae type XIV polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
Microbe NameStreptococcus pneumoniae type XIV   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureHeat killed cells
Carrier NameNil
Conjugate MethodNil
AntibodiesMab F9
Antibody Type ClassIgM
Assay SystemHemagglutination, ELISA, Cryoprecipitation and cryoprecipitation-inhibition assays
Cross ReactivityThis Mab cross-reacted with rabbit and human erythrocytes at temperatures below 37°C. This Mab also reacted with phenylLac-BGG
Proposed EpitopeThis Mab was specific for N-acetyl-lactosamine, the immunodominant sugar residue expressed on type XIV polysaccharide
IEDB EpitopeN/A
Proposed UtilityThis Mab precipitated at low temperatures and also reacted with rabbit and human erythrocytes at low temperature
Curator IDAA + AS
Date of Curation11-05-2011
References3989304

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PolysacDB ID2430
Carbohydrate NameStreptococcus pneumoniae type XIV polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
Microbe NameStreptococcus pneumoniae type XIV   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureHeat killed cells
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 4AC10
Antibody Type ClassIgM
Assay SystemHemagglutination, ELISA, Cryoprecipitation and cryoprecipitation-inhibition assays
Cross ReactivityThis Mab cross-reacted with rabbit and human erythrocytes at temperatures below 37°C. This Mab also reacted with phenylLac-BGG
Proposed EpitopeThis Mab was specific for N-acetyl-lactosamine, the immunodominant sugar residue expressed on type XIV polysaccharide
IEDB EpitopeN/A
Proposed UtilityThis Mab precipitated at low temperatures and also reacted with rabbit and human erythrocytes at low temperature
Curator IDAA + AS
Date of Curation11-05-2011
References3989304

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PolysacDB ID2431
Carbohydrate NameStreptococcus pneumoniae type XIV polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
Microbe NameStreptococcus pneumoniae type XIV   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureHeat killed cells
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 4AC5
Antibody Type ClassIgM
Assay SystemHemagglutination, ELISA, Cryoprecipitation and cryoprecipitation-inhibition assays
Cross ReactivityThis Mab cross-reacted with rabbit and human erythrocytes at temperatures below 37°C. This Mab also reacted with phenylLac-BGG
Proposed EpitopeThis Mab was specific for N-acetyl-lactosamine, the immunodominant sugar residue expressed on type XIV polysaccharide
IEDB EpitopeN/A
Proposed UtilityThis Mab precipitated at low temperatures and also reacted with rabbit and human erythrocytes at low temperature
Curator IDAA + AS
Date of Curation11-05-2011
References3989304

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PolysacDB ID2432
Carbohydrate NameStreptococcus pneumoniae type XIV polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
Microbe NameStreptococcus pneumoniae type XIV   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureHeat killed cells
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 4BF5
Antibody Type ClassIgM
Assay SystemHemagglutination, ELISA, Cryoprecipitation and cryoprecipitation-inhibition assays
Cross ReactivityThis Mab cross-reacted with rabbit and human erythrocytes at temperatures below 37°C. This Mab also reacted with phenylLac-BGG
Proposed EpitopeThis Mab was specific for N-acetyl-lactosamine, the immunodominant sugar residue expressed on type XIV polysaccharide
IEDB EpitopeN/A
Proposed UtilityThis Mab precipitated at low temperatures and also reacted with rabbit and human erythrocytes at low temperature
Curator IDAA + AS
Date of Curation12-05-2011
References3989304

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PolysacDB ID2433
Carbohydrate NameStreptococcus pneumoniae type XIV polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
Microbe NameStreptococcus pneumoniae type XIV   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureHeat killed cells
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 5DB4
Antibody Type ClassIgM
Assay SystemHemagglutination, ELISA, Cryoprecipitation and cryoprecipitation-inhibition assays
Cross ReactivityThis Mab cross-reacted with rabbit and human erythrocytes at temperatures below 37°C. This Mab also reacted with phenylLac-BGG
Proposed EpitopeThis Mab was specific for N-acetyl-lactosamine, the immunodominant sugar residue expressed on type XIV polysaccharide
IEDB EpitopeN/A
Proposed UtilityThis Mab precipitated at low temperatures and also reacted with rabbit and human erythrocytes at low temperature
Curator IDAA + AS
Date of Curation12-05-2011
References3989304

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