PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
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PolysacDB ID2469
Carbohydrate NameSurface polysaccharide antigen   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
Microbe NameEubacterium saburreum strain L32   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe PS L32 polymer is built up of repeating trisaccharide units of galactose, ribose and dideoxyhexose
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureWhole cells
Carrier NameNil
Conjugate MethodNil
AntibodiesAntisera
Antibody Type ClassIgM
Assay SystemPrecipitation tests, immunoelectrophoresis and complement fixation
Cross ReactivityN/A
Proposed EpitopeThe dideoxyhexose is the immunodominant sugar
IEDB EpitopeN/A
Proposed UtilityN/A
Curator IDAA + AS
Date of Curation27-05-2011
References670929

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PolysacDB ID2470
Carbohydrate NameSurface polysaccharide antigen   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
Microbe NameEubacterium saburreum strain T18   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThis antigen was composed of D-glycero-D-galacto-heptose
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureWhole cells
Carrier NameNil
Conjugate MethodNil
AntibodiesAntisera
Antibody Type ClassIgM
Assay SystemImmunoprecipitation, immunodiffusion
Cross ReactivityThis antisera was specific to T18 antigen and did not cross-react with L44 antigen and T27 antigen
Proposed EpitopeD-glycero-D-galacto-heptose constitutes part of the immunodeterminant of the antigenic polysaccharide
IEDB EpitopeN/A
Proposed UtilityThe polysaccharide antigen from strain T18 is distinct from those previously reported for this species and may be useful in serotyping E. saburreum
Curator IDAA + AS
Date of Curation28-05-2011
ReferencesPMC260431

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