PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
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PolysacDB ID2391
Carbohydrate NameType a polysaccharide antigens   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
Microbe NameStreptococcus sobrinus   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureWhole cells
Carrier NameNil
Conjugate MethodNil
AntibodiesMab a-4
Antibody Type ClassIgM
Assay SystemRadioimmunoassay, double immunodiffusion, precipitin inhibition tests
Cross ReactivityThe MAb reacted with the cells of HS1 and E49 (S. cricetus, type a), MT615R and B13 (S. sobrinus, type d), and MF25 and BFe12 (S. sobrinus, type h)
Proposed EpitopeGalactose-α-1,6-glucose is the predominant antigenic determinant of this cross-reactive antigen
IEDB EpitopeN/A
Proposed UtilityThis Mab may be useful for studying polysaccharide antigens on Streptococci
Curator IDAA + AS
Date of Curation27-04-2011
ReferencesPMC260314

Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036