PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
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PolysacDB ID2175
Carbohydrate NameVi antigen   (Drugpedia)
Carbohydrate ClassGlycoprotein
Microbe NameSalmonella typhi 620Ty   (NCBI Taxonomy)   (Drugpedia)
Basic StructureVi antigen is a linear homopolymer of 1-->4(2-deoxy-2-N-acetylgalacturonic acid)
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NaturePurified Vi antigen
Carrier NameNil
Conjugate MethodNil
AntibodiesMab Vi4a
Antibody Type ClassIgG2b
Assay SystemPassive hemagglutination (PHA) and enzyme-linked immunosorbent assay (ELISA), Whole-cell radioimmunoassay, dot radioimmunoassay
Cross ReactivityThis Mab recognized the Vi antigen in Citrobacter strain 5396/38 and also reacted with the Vi antigens in S. typhi and S. dublin strains
Proposed EpitopeN/A
IEDB EpitopeN/A
Proposed UtilityThe Vi-agglutiniating ability of the Mab might have application in the identification of S. typhi
Curator IDAA + AS
Date of Curation22-02-2011
ReferencesPMC265979

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PolysacDB ID2176
Carbohydrate NameVi antigen   (Drugpedia)
Carbohydrate ClassGlycoprotein
Microbe NameSalmonella typhi 620Ty   (NCBI Taxonomy)   (Drugpedia)
Basic StructureVi antigen is a linear homopolymer of 1-->4(2-deoxy-2-N-acetylgalacturonic acid)
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NaturePurified Vi antigen
Carrier NameNil
Conjugate MethodNil
AntibodiesMab Vi5a
Antibody Type ClassIgG2b
Assay SystemPassive hemagglutination (PHA) and enzyme-linked immunosorbent assay (ELISA), Whole-cell radioimmunoassay, dot radioimmunoassay
Cross ReactivityThis Mab recognized the Vi antigen in Citrobacter strain 5396/38 and also reacted with the Vi antigens in S. typhi and S. dublin strains
Proposed EpitopeN/A
IEDB EpitopeN/A
Proposed UtilityThe Vi-agglutiniating ability of the Mab might have application in the identification of S. typhi
Curator IDAA + AS
Date of Curation22-02-2011
ReferencesPMC265979

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PolysacDB ID2177
Carbohydrate NameVi antigen   (Drugpedia)
Carbohydrate ClassGlycoprotein
Microbe NameSalmonella typhi 620Ty   (NCBI Taxonomy)   (Drugpedia)
Basic StructureVi antigen is a linear homopolymer of 1-->4(2-deoxy-2-N-acetylgalacturonic acid)
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NaturePurified Vi antigen
Carrier NameNil
Conjugate MethodNil
AntibodiesMab Vi6a
Antibody Type ClassIgG2b
Assay SystemPassive hemagglutination (PHA) and enzyme-linked immunosorbent assay (ELISA), Whole-cell radioimmunoassay, dot radioimmunoassay
Cross ReactivityThis Mab recognized the Vi antigen in Citrobacter strain 5396/38 and also reacted with the Vi antigens in S. typhi and S. dublin strains
Proposed EpitopeN/A
IEDB EpitopeN/A
Proposed UtilityThe Vi-agglutiniating ability of the Mab might have application in the identification of S. typhi
Curator IDAA + AS
Date of Curation23-02-2011
ReferencesPMC265979

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PolysacDB ID2178
Carbohydrate NameVi antigen   (Drugpedia)
Carbohydrate ClassGlycoprotein
Microbe NameSalmonella typhi 620Ty   (NCBI Taxonomy)   (Drugpedia)
Basic StructureVi antigen is a linear homopolymer of 1-->4(2-deoxy-2-N-acetylgalacturonic acid)
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NaturePurified Vi antigen
Carrier NameNil
Conjugate MethodNil
AntibodiesMab Vi7a
Antibody Type ClassIgG3
Assay SystemPassive hemagglutination (PHA) and enzyme-linked immunosorbent assay (ELISA), Whole-cell radioimmunoassay, dot radioimmunoassay
Cross ReactivityThis Mab recognized the Vi antigen in Citrobacter strain 5396/38 and also reacted with the Vi antigens in S. typhi and S. dublin strains
Proposed EpitopeN/A
IEDB EpitopeN/A
Proposed UtilityThe Vi-agglutiniating ability of the Mab might have application in the identification of S. typhi
Curator IDAA + AS
Date of Curation23-02-2011
ReferencesPMC265979

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