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Details of SAPdb entry with Sequence KΔPhe
Primary information
SAPdb ID 1295,
PMID22915849
Peptide NameLysine-dehydrophenylalanine (KΔF)
Peptide sequenceKΔPhe
N-Terminal ModificationFree
C-Terminal ModificationFree
Non-Terminal ModificationΔPhe=Dehydrophenylalanine
Length2
Peptide/ConjuagatePeptide
TechniqueTEM (Transmission Electron Microscopy), DLS (Dynamic light - scattering)
SolventMethanol and water (50:50; v/v).
MethodStock solutions were prepared by dissolving 2 mg of peptide in 50 μL of methanol, solution is sonicated to dissolve. Assembly was initiated by addition of 1 mL of aqueous methanol (50% v/v) to the stock. Samples were incubated for 24 hours.
Conc2mg/ml
TemperatureRoom temperature
Incubation Time24 hours
Year2012
Self assemblyNo
Type of Self assemblyNo Nanoparticle formation
Tertiary Structure
(Technique)		Not Predicted),
Linear
NA
NA
None
NA
KF
N.A.
Primary information
SAPdb ID 1322,
PMID23398497
Peptide NameLys–alpha, beta-dehydrophenylalanine
Peptide sequenceKΔPhe
N-Terminal ModificationFree
C-Terminal ModificationFree
Non-Terminal ModificationΔPhe=Dehydrophenylalanine
Length2
Peptide/ConjuagatePeptide
TechniqueTEM (Transmission Electron Microscopy)
SolventHFIP (1,1,1,3,3,3-hexafluoro-2-Isopropanol) + water
MethodDipeptide (2 mg) dissolved in HFIP and subsequently dilution with 1 ml of water. Dipeptide nanoparticles (DNPs) so formed were aged for 2 h.
Conc2mg/ml
TemperatureRoom temperature
Incubation Time2 hours
Year2012
Self assemblyYes
Type of Self assemblyNanoparticle
Tertiary Structure
(Technique)		Not Predicted),
Linear
NA
Stable in 10 % FBS (Fetal bovine Serum) for 1 month
Nanoparticle
370
KF
N.A.
Primary information
SAPdb ID 1324,
PMID23398497
Peptide NameLys–alpha, beta-dehydrophenylalanine
Peptide sequenceKΔPhe
N-Terminal ModificationFree
C-Terminal ModificationFree
Non-Terminal ModificationΔPhe=Dehydrophenylalanine
Length2
Peptide/ConjuagatePeptide
TechniqueTEM (Transmission Electron Microscopy)
SolventHFIP (1,1,1,3,3,3-hexafluoro-2-Isopropanol) + water
MethodDipeptide (5 mg) dissolved in HFIP and subsequently dilution with 1 ml of water. Dipeptide nanoparticles (DNPs) so formed were aged for 2 h.
Conc5mg/ml
TemperatureRoom temperature
Incubation Time2 hours
Year2012
Self assemblyYes
Type of Self assemblyNanoparticle
Tertiary Structure
(Technique)		Not Predicted),
Linear
NA
Stable in 10 % FBS (Fetal bovine Serum) for 6 hours
Nanoparticle
400
KF
N.A.
Primary information
SAPdb ID 1326,
PMID23398497
Peptide NameLys–alpha, beta-dehydrophenylalanine
Peptide sequenceKΔPhe
N-Terminal ModificationFree
C-Terminal ModificationFree
Non-Terminal ModificationΔPhe=Dehydrophenylalanine
Length2
Peptide/ConjuagatePeptide
TechniqueTEM (Transmission Electron Microscopy)
SolventHFIP (1,1,1,3,3,3-hexafluoro-2-Isopropanol) + water
MethodDipeptide (10 mg) dissolved in HFIP and subsequently dilution with 1 ml of water. Dipeptide nanoparticles (DNPs) so formed were aged for 2 h.
Conc10mg/ml
TemperatureRoom temperature
Incubation Time2 hours
Year2012
Self assemblyYes
Type of Self assemblyNanoparticle
Tertiary Structure
(Technique)		Not Predicted),
Linear
NA
Stable in 10 % FBS (Fetal bovine Serum) for 6 hours
Nanoparticle
445
KF
N.A.
Primary information
SAPdb ID 1334,
PMID23800286
Peptide NameLys-ΔPhe
Peptide sequenceKΔPhe
N-Terminal ModificationFree
C-Terminal ModificationFree
Non-Terminal ModificationΔPhe=Dehydrophenylalanine
Length2
Peptide/ConjuagatePeptide
TechniqueTEM (Transmission Electron Microscopy) and DLS (Dynamic Light scattering)
SolventHFIP (1,1,1,3,3,3-hexafluoro-2-Isopropanol)+ water
Method2 mg of cationic peptides were first dissolved in 20 μl of HFIP and then diluted with 1 ml of water to form self-assembled Nps.
Conc2mg/ml
Year2013
Self assemblyYes
Type of Self assemblyNanoparticle
Tertiary Structure
(Technique)		Not Predicted),
Linear
NA
NA
Nanoparticle
400
KF
N.A.
Primary information
SAPdb ID 1336,
PMID23800286
Peptide NameLys-ΔPhe
Peptide sequenceKΔPhe
N-Terminal ModificationFree
C-Terminal ModificationFree
Non-Terminal ModificationΔPhe=Dehydrophenylalanine
Length2
Peptide/ConjuagatePeptide
TechniqueTEM (Transmission Electron Microscopy) and DLS (Dynamic Light scattering)
SolventHFIP (1,1,1,3,3,3-hexafluoro-2-Isopropanol)+ water
Method2 mg of cationic peptides were first dissolved in 20 μl of HFIP and then diluted with 1 ml of water to form self-assembled Nps.
Conc2mg/ml
Year2013
Self assemblyYes
Type of Self assemblyNanoparticle
Tertiary Structure
(Technique)		Not Predicted),
Linear
In presence of 25–100 μg of DNA
Stable to enzymatic degradation (DNAse)
Nanoparticle
140
KF
N.A.
Primary information
SAPdb ID 1497,
PMID18358051
Peptide NameLys-Δphe (Lysine -dehydrophenylalanine)
Peptide sequenceKΔPhe
N-Terminal ModificationFree
C-Terminal ModificationFree
Non-Terminal ModificationΔPhe=Dehydrophenylalanine
Length2
Peptide/ConjuagatePeptide
Conjugate partnerNone
TechniqueTEM (Transmission Electron Microscopy) and DLS (Dynamic Light scattering)
Solvent1,1,1,3,3,3-hexa-fluoro-isopropanol + Water
Method1-10 mg of the peptide in a small volume (50 íL) of HFIP and subsequent addition of 1 mL of water at near neutral pH
Conc1-10 mg/mL
Temperature7
Incubation Time24 hours
Year2008
Self assemblyYes
Type of Self assemblyNanovesicles
Tertiary Structure
(Technique)		Not Predicted),
Linear
NA
Stable to proteinase K and non-specific proteases treatment; Stable in presence of mono or divalent cations
Nanovesicle
370
KF
N.A.