Primary information |
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SAPdb_ID | 1113 |
PMID | 22955637 |
Year | 2012 |
Name | D- Leu-L-phe-L-phe |
Sequence | lFF |
N-Terminal Modification | Free |
C-Terminal Modification | Free |
Non-terminal Modication | None |
Length | 3 |
Peptide/Conjugate/Mixture | Peptide |
Conjugate Partner | None |
Technique | TEM (Transmission Electron Microscopy), Cryo - TEM (Transmission Electron Microscopy), AFM (Atomic Force Microscopy), CD (Circular Dichroism spectroscopy) and XRD |
Solvent | sodium phosphate buffer |
Method | 4.0 mg of peptide was dissolved in 300 ml of 0.1 M sodium phosphate buffer, pH 11.8 (buffer A), with the aid of sonication for 5 min, then diluted 1 : 1 with another 300 ml of 0.1 M sodium phosphate buffer, pH 5.6–5.7 (buffer B) to yield a final pH of 7.4. Samples were sonicated for another 5 min . Samples left for 24 hours for the formation of gel. |
Concentration | 10mg/ml |
pH | pH12 |
Temperature
| NA |
Incubation Period | 24 hours- 72 hours |
Self-Assembly Formation | Yes |
Type of Self-Assembly | Globular structure |
Size of Self-Assembled structure | Diameter : ~3um |
Linear/Cyclic | Linear |
Stability of Nanostructure | NA |
Comment | NA |
Secondary information |
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Physico-Chemical properties | |
STRUCTURE | |
SMILES | N[C@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C=O |