| Primary information |
|---|
| SAPdb_ID | 1122 |
| PMID | 21472901 |
| Year | 2011 |
| Name | 1 or Boc-{(N-Cbz)-Lys}-Phe-Ala |
| Sequence | KFA |
| N-Terminal Modification | N-Cbz lysine (Cbz = benzyloxy-carbonyl) and Boc (N-t-Butoxycarbonyl) |
| C-Terminal Modification | Free |
| Non-terminal Modication | None |
| Length | 3 |
| Peptide/Conjugate/Mixture | Peptide derivative |
| Conjugate Partner | Coupling with 5,5’-dibromomethyl-2,2’-bipyridin |
| Technique | TEM (Transmission Electron Microscopy), SEM (Scanning Electron Microscopy) NMR and Mass spectrometery |
| Solvent | THF (Tetrahydrofuran):Water (1:1) |
| Method | Conjugate 1 was dissolved in THF at a concentration of 4.0mg/mL. Addition of the same amount of water into the prior solution in THF resulted in a transparent solution and the formation of vesicles. Upon ultrasound treatment for about 10 mins, the vesicles transferred into networks of nanofibers. The nanofibers rearranged into vesicles upon incubation in the 60 C water bath. |
| Concentration | 2mg/ml |
| pH | NA |
Temperature
| 60°C |
| Incubation Period | 20-30minutes |
| Self-Assembly Formation | Yes |
| Type of Self-Assembly | vesicle structure |
| Size of Self-Assembled structure | NA |
| Linear/Cyclic | Linear |
| Stability of Nanostructure | Stable |
| Comment | NA |
| Secondary information |
|---|
| Physico-Chemical properties | |
| STRUCTURE | |
| SMILES | N.A. |
