Details of SAPdb ID 1227 |
| Primary information | ||
|---|---|---|
| SAPdb_ID | 1227 | |
| PMID | 25384556 | |
| Year | 2015 | |
| Name | Compound A | |
| Sequence | KK | |
| N-Terminal Modification | Acetylation | |
| C-Terminal Modification | Amidation | |
| Non-terminal Modication | None | |
| Length | 2 | |
| Peptide/Conjugate/Mixture | Conjugate | |
| Conjugate Partner | Camptothecin (CPT) -conjugated | |
| Technique | TEM (Transmission Electron Microscopy) | |
| Solvent | Phosphate buffer saline | |
| Method | Samples were prepared by dissolving CPT–dipeptides in PBS (10 mm), then diluting to 1 mm after 24 h. | |
| Concentration | Preincubation at 10mM for 24 h, 1mM for rest 48 hours | |
| pH | 7.4 | |
| Temperature | 37°C | |
| Incubation Period | 72 hours | |
| Self-Assembly Formation | Yes | |
| Type of Self-Assembly | Nanotubes | |
| Size of Self-Assembled structure | Diameter 80–120 nm; Length : several micrometer | |
| Linear/Cyclic | Linear | |
| Stability of Nanostructure | Stable at 37°C | |
| Comment | NA | |
| Secondary information | ||
| Physico-Chemical properties |
| |
| STRUCTURE |
| |
| SMILES | CC(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N | |