Primary information |
---|
SAPdb_ID | 1228 |
PMID | 25384556 |
Year | 2015 |
Name | Compound B |
Sequence | KK |
N-Terminal Modification | Free |
C-Terminal Modification | Amidation |
Non-terminal Modication | None |
Length | 2 |
Peptide/Conjugate/Mixture | Conjugate |
Conjugate Partner | Camptothecin (CPT) -conjugated |
Technique | TEM (Transmission Electron Microscopy) |
Solvent | Water or Phosphate buffer saline |
Method | Samples were prepared by dissolving CPT–dipeptides in PBS (10 mm), then diluting to 1 mm after 24 h. |
Concentration | Preincubation at 10mM for 24 h, 1mM for rest 48 hours |
pH | 7.4 |
Temperature
| 37°C |
Incubation Period | 72 hours |
Self-Assembly Formation | Yes |
Type of Self-Assembly | Nanotubes |
Size of Self-Assembled structure | Diameter 80–120 nm; Length : several micrometer |
Linear/Cyclic | Linear |
Stability of Nanostructure | Stable at 37°C |
Comment | NA |
Secondary information |
---|
Physico-Chemical properties | |
STRUCTURE | |
SMILES | N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N |