SAPdb: Entry Card with Detailed Information of Peptide

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Details of SAPdb ID 1289
Primary information
SAPdb_ID1289
PMID22897679
Year2012
Name(polyA-FF-ME) or Poly(N-acryloyl-L-phenylalanyl-L-phenylalanine methyl ester)
SequenceFF
N-Terminal ModificationAcryloyl
C-Terminal ModificationMethyl esterification
Non-terminal ModicationNone
Length2
Peptide/Conjugate/MixtureMixture
Conjugate PartnerPVP (Polyvinylpyrrolidone) and BP (benzoyl peroxide)
TechniqueHR - SEM (High Resolution Scanning Electron Microscopy)
SolventMethoxy-ethanol
Method30 mg of the vinylic monomer A-FF-ME, 10 mg PVP, and 2 mg of BP were added to 1 mL of nitrogen-bubbled 2-methoxy ethanol.The mixture was shaken at room temperature to dissolve the solids at conc 3% 1%, and 0.2% (w/v) AA-FF-ME, PVP, and BP, respectively. The mixture was then shaken at 75 οC for 18 h. The formed soluble polyA-FF-ME wasprecipitated as uniform nanoparticles by adding 100 μL of its solution to 1 mL distilled water.
Concentration3% w/v
pHNA
Temperature
75°C
Incubation Period18 hours
Self-Assembly FormationYes
Type of Self-AssemblyNanoparticle
Size of Self-Assembled structure57 ± 6 nm
Linear/CyclicLinear
Stability of NanostructureStable for more than 233 h of heating
CommentNA
Secondary information
Physico-Chemical properties
Physico-Chemical properties
STRUCTURE
Predicted Structure
SMILESN.A.