Details of SAPdb ID 1301 |
| Primary information | ||
|---|---|---|
| SAPdb_ID | 1301 | |
| PMID | 23061818 | |
| Year | 2012 | |
| Name | Boc-Phe-Phe-OH and NH2-Phe-Phe-OH | |
| Sequence | FF | |
| N-Terminal Modification | Boc (t-butoxycarbonyl) on 1st dipeptide | |
| C-Terminal Modification | Free | |
| Non-terminal Modication | None | |
| Length | 2 | |
| Peptide/Conjugate/Mixture | Mixture | |
| Conjugate Partner | Boc-Phe-Phe-OH + NH2-Phe-Phe-OH | |
| Technique | SEM (Scanning Electron Microscopy), HR - SEM (High Resolution Scanning Electron Microscopy), TEM (Transmission Electron Microscopy), AFM (Atomic force Microscopy) | |
| Solvent | HFP (1,1,1,3,3,3-hexafluoro-2-propanol) + 50% ethanol + 16 mMNaCl | |
| Method | To coassemble the two peptides, we dissolved each peptide in 1,1,1,3,3,3-hexafluoro-2-propanol (HFP) and diluted them in 50% ethanol. The polarized solvent allowed the selfassembly of peptides. | |
| Concentration | 5mg/ml (1st dipeptide) + 2mg/ml )2nd dipeptide | |
| pH | ~ 4.5 | |
| Temperature | Room temperature | |
| Incubation Period | 10 -24 hours | |
| Self-Assembly Formation | Yes | |
| Type of Self-Assembly | Spherical structures with branching fibers | |
| Size of Self-Assembled structure | Diameter : 800nm - 2μm | |
| Linear/Cyclic | Linear | |
| Stability of Nanostructure | Stable upto at 70°C | |
| Comment | Co-assembly of two dipeptides | |
| Secondary information | ||
| Physico-Chemical properties |
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| STRUCTURE |
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| SMILES | N.A. | |