Primary information |
---|
SAPdb_ID | 1441 |
PMID | 23566763 |
Year | 2013 |
Name | Fmoc-FF |
Sequence | FF |
N-Terminal Modification | Fmoc(fluorenylmethoxycarbonyl) |
C-Terminal Modification | Free |
Non-terminal Modication | None |
Length | 2 |
Peptide/Conjugate/Mixture | Peptide |
Conjugate Partner | NA |
Technique | SEM (Scanning Electron Microscopy) and DLS (Dynamic Light Scattering) |
Solvent | DMSO + water + vitamin E-TPGS |
Method | Peptide dissolved in water at concentration of 10 mg/mL. The resulting solution was added drop-wise into 50 mL slightly warmed ( 35 °C) mineral oil containing vitamin E-TPGS atconcentration of 0.4% wt/v and homogenized . Next, nanoparticles were allowed to self-assemble for 2 h with continues stirring at 4 °C. After completion the self assembly process, the resulting suspension was mixed with hexane at a concentration of 20% (v/v), and centrifuged to obtain self assembled nanoparticle. |
Concentration | 10mg/ml |
pH | NA |
Temperature
| 4 °C |
Incubation Period | 2 hours |
Self-Assembly Formation | Yes |
Type of Self-Assembly | Hydrogel Nanoparticle (HNP) |
Size of Self-Assembled structure | TEM (Diameter: 100nm); DLS(Size: 21.5 ± 1.3nm; 225.9 ± 0.8 nm) |
Linear/Cyclic | Linear |
Stability of Nanostructure | Stable under physiological conditions |
Comment | NA |
Secondary information |
---|
Physico-Chemical properties | |
STRUCTURE | |
SMILES | N.A. |