SAPdb: Entry Card with Detailed Information of Peptide

Welcome to Entry Card of Peptide


Details of SAPdb ID 1441
Primary information
SAPdb_ID1441
PMID23566763
Year2013
NameFmoc-FF
SequenceFF
N-Terminal ModificationFmoc(fluorenylmethoxycarbonyl)
C-Terminal ModificationFree
Non-terminal ModicationNone
Length2
Peptide/Conjugate/MixturePeptide
Conjugate PartnerNA
TechniqueSEM (Scanning Electron Microscopy) and DLS (Dynamic Light Scattering)
SolventDMSO + water + vitamin E-TPGS
MethodPeptide dissolved in water at concentration of 10 mg/mL. The resulting solution was added drop-wise into 50 mL slightly warmed ( 35 °C) mineral oil containing vitamin E-TPGS atconcentration of 0.4% wt/v and homogenized . Next, nanoparticles were allowed to self-assemble for 2 h with continues stirring at 4 °C. After completion the self assembly process, the resulting suspension was mixed with hexane at a concentration of 20% (v/v), and centrifuged to obtain self assembled nanoparticle.
Concentration10mg/ml
pHNA
Temperature
4 °C
Incubation Period2 hours
Self-Assembly FormationYes
Type of Self-AssemblyHydrogel Nanoparticle (HNP)
Size of Self-Assembled structureTEM (Diameter: 100nm); DLS(Size: 21.5 ± 1.3nm; 225.9 ± 0.8 nm)
Linear/CyclicLinear
Stability of NanostructureStable under physiological conditions
CommentNA
Secondary information
Physico-Chemical properties
Physico-Chemical properties
STRUCTURE
Predicted Structure
SMILESN.A.