Details of SAPdb ID 1441 |
| Primary information | ||
|---|---|---|
| SAPdb_ID | 1441 | |
| PMID | 23566763 | |
| Year | 2013 | |
| Name | Fmoc-FF | |
| Sequence | FF | |
| N-Terminal Modification | Fmoc(fluorenylmethoxycarbonyl) | |
| C-Terminal Modification | Free | |
| Non-terminal Modication | None | |
| Length | 2 | |
| Peptide/Conjugate/Mixture | Peptide | |
| Conjugate Partner | NA | |
| Technique | SEM (Scanning Electron Microscopy) and DLS (Dynamic Light Scattering) | |
| Solvent | DMSO + water + vitamin E-TPGS | |
| Method | Peptide dissolved in water at concentration of 10 mg/mL. The resulting solution was added drop-wise into 50 mL slightly warmed ( 35 °C) mineral oil containing vitamin E-TPGS atconcentration of 0.4% wt/v and homogenized . Next, nanoparticles were allowed to self-assemble for 2 h with continues stirring at 4 °C. After completion the self assembly process, the resulting suspension was mixed with hexane at a concentration of 20% (v/v), and centrifuged to obtain self assembled nanoparticle. | |
| Concentration | 10mg/ml | |
| pH | NA | |
| Temperature | 4 °C | |
| Incubation Period | 2 hours | |
| Self-Assembly Formation | Yes | |
| Type of Self-Assembly | Hydrogel Nanoparticle (HNP) | |
| Size of Self-Assembled structure | TEM (Diameter: 100nm); DLS(Size: 21.5 ± 1.3nm; 225.9 ± 0.8 nm) | |
| Linear/Cyclic | Linear | |
| Stability of Nanostructure | Stable under physiological conditions | |
| Comment | NA | |
| Secondary information | ||
| Physico-Chemical properties |
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| STRUCTURE |
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| SMILES | N.A. | |