Primary information |
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SAPdb_ID | 1443 |
PMID | 24085660 |
Year | 2013 |
Name | Fmoc-LL |
Sequence | LL |
N-Terminal Modification | Fmoc(fluorenylmethoxycarbonyl) |
C-Terminal Modification | Free |
Non-terminal Modication | None |
Length | 2 |
Peptide/Conjugate/Mixture | Peptide |
Conjugate Partner | NA |
Technique | TEM (Transmission Electron Microscopy) and WAXS(Wide Angle X - Ray scattering) |
Solvent | Water + 0.1M Hcl + 0.5 M NaOH |
Method | Fmoc-dipeptide was suspended in water. Sodium hydroxide (0.5 M) was gradually added to the aqueous suspensions of Fmoc-dipeptide until pH 10.5 was reached. The samples were vortexed and sonicated for one minute to fully dissolve the peptide amphiphiles. To obtain required pH, a required volume of dilute hydrochloric acid (0.085 M) was then added dropwise to the solution. Solution sonicated and vortexed. Next, the samples were heated to 75–80 ◦C until fully dissolved and homogenised. The samples were subsequently cooled and maintained at 4 ◦C for ∼ 12 hours (overnight) to promote gelation. |
Concentration | 10mmol/L |
pH | pH 4.3 - 6.8 |
Temperature
| 4 °C |
Incubation Period | ~ 12 hours |
Self-Assembly Formation | Yes |
Type of Self-Assembly | Nanofibers |
Size of Self-Assembled structure | NA |
Linear/Cyclic | Linear |
Stability of Nanostructure | NA |
Comment | NA |
Secondary information |
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Physico-Chemical properties | |
STRUCTURE | |
SMILES | N.A. |