Details of SAPdb ID 1445 |
| Primary information | ||
|---|---|---|
| SAPdb_ID | 1445 | |
| PMID | 24085660 | |
| Year | 2013 | |
| Name | Fmoc-LG | |
| Sequence | LG | |
| N-Terminal Modification | Fmoc(fluorenylmethoxycarbonyl) | |
| C-Terminal Modification | Free | |
| Non-terminal Modication | None | |
| Length | 2 | |
| Peptide/Conjugate/Mixture | Peptide | |
| Conjugate Partner | NA | |
| Technique | TEM (Transmission Electron Microscopy) and WAXS(Wide Angle X - Ray scattering) | |
| Solvent | Water + 0.1M Hcl + 0.5 M NaOH | |
| Method | Fmoc-dipeptide was suspended in water. Sodium hydroxide (0.5 M) was gradually added to the aqueous suspensions of Fmoc-dipeptide until pH 10.5 was reached. The samples were vortexed and sonicated for one minute to fully dissolve the peptide amphiphiles. To obtain required pH, a required volume of dilute hydrochloric acid (0.085 M) was then added dropwise to the solution. Solution sonicated and vortexed. Next, the samples were heated to 75–80 ◦C until fully dissolved and homogenised. The samples were subsequently cooled and maintained at 4 ◦C for ∼ 12 hours (overnight) to promote gelation. | |
| Concentration | 10mmol/L | |
| pH | pH 7.6 | |
| Temperature | 4 °C | |
| Incubation Period | ~ 12 hours | |
| Self-Assembly Formation | Yes | |
| Type of Self-Assembly | Nanoribbon | |
| Size of Self-Assembled structure | Width: 24 +/- 1.7nm | |
| Linear/Cyclic | Linear | |
| Stability of Nanostructure | NA | |
| Comment | NA | |
| Secondary information | ||
| Physico-Chemical properties |
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| STRUCTURE |
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| SMILES | N.A. | |