A database of FDA approved therapeutic peptides and proteins
ID | ThPPID | Name | Peptide Sequence | Length | Functional Classification | Disease | Brand | Company | Physical Appearance | Route of Administartion | Category | Target |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1129 | Th1018 | Secretin | HSDGTFTSELSRLRDSARLQ Full view | 27 | IV | Hormonal disorders | SecreFlo | Repligen Corp | Lyophilized white powder | Intravenous infusion | Diagnostic Agents | Secretin receptor |
1130 | Th1018 | Secretin | HSDGTFTSELSRLRDSARLQ Full view | 27 | IV | Hormonal disorders | Secremax | Repligen Corp | Solution | Intravenous | Diagnostic Agents | Secretin receptor |
1205 | Th1027 | Insulin Regular | A-chain:GIVEQCCTSIC< Full view | 51 | Ia | Genetic/Hormonal | Humulin R | Eli Lilly and Company | Sterile, clear, aqueous, and colorless solution | Subcutaneous injection in the abdominal wall, the thigh, the gluteal region or in the upper arm and Intravenousadministration of Humulin R (insulin (human recombinant)) U-100 is possible under medical supervision. | Antidiabetic Agents | Insulin receptor,Insulin-like growth factor 1 receptor,Retinoblastoma-associated protein,Cathepsin D,Insulin-degrading enzyme,Neuroendocrine convertase 2,Carboxypeptidase E,Neuroendocrine convertase 1,Protein NOV homolog,Low-density lipoprotein receptor-r |
1206 | Th1027 | Insulin Regular | A-chain:GIVEQCCTSIC< Full view | 51 | Ia | Genetic/Hormonal | Novolin R | Novo Nordisk | Sterile, clear, aqueous, and colorless solution | Subcutaneous and Intravenous infusion | Antidiabetic Agents | Insulin receptor,Insulin-like growth factor 1 receptor,Retinoblastoma-associated protein,Cathepsin D,Insulin-degrading enzyme,Neuroendocrine convertase 2,Carboxypeptidase E,Neuroendocrine convertase 1,Protein NOV homolog,Low-density lipoprotein receptor-r |
1215 | Th1029 | Menotropins | Alpha-Chain(LH):APD< Full view | 222 | Ib | Hormonal disorders | Menopur | N.A. | Sterile, lyophilized powder which is reconstitution with sterile 0.9% Sodium Chloride Injection. | Subcutaneous Injection | Fertility Agents | Follicle-stimulating hormone receptor,Lutropin-choriogonadotropic hormone receptor |
1216 | Th1029 | Menotropins | Alpha-Chain(LH):APD< Full view | 222 | Ib | Hormonal disorders | Repronex | N.A. | Sterile, lyophilized form | Subcutaneous or Intramuscular Injection. | Fertility Agents | Follicle-stimulating hormone receptor,Lutropin-choriogonadotropic hormone receptor |
1252 | Th1035 | Glucagon recombinant | HSQGTFTSDYSKYLDSRRAQ Full view | 29 | IV | Hormonal/Metabolic/genetic | GlucaGen | Novo Nordisk | Sterile, lyophilized white powder | Subcutaneous, Intramuscular, or Intravenous infusion | Hypoglycemic Agents | Glucagon receptor,Glucagon-like peptide 2 receptor,Glucagon-like peptide 1 receptor |
1253 | Th1035 | Glucagon recombinant | HSQGTFTSDYSKYLDSRRAQ Full view | 29 | IV | Hormonal/Metabolic/genetic | Glucagon | Eli Lilly | Powder | Subcutaneously or Intramuscularly Injection | Hypoglycemic Agents | Glucagon receptor,Glucagon-like peptide 2 receptor,Glucagon-like peptide 1 receptor |
1269 | Th1039 | Lutropin alfa | Alpha Chain: APDVQDC Full view | 213 | Ib | Hormonal | Luveris | Serono | White lyophilised pellet withg clear colourless solvent to make solution | Subcutaneous (SC) administration | Fertility Agents | Lutropin-choriogonadotropic hormone receptor |
1275 | Th1040 | Insulin Lispro | A chain:GIVEQCCTSICS Full view | 51 | Ia | Hormonal/Metabolic/genetic | Humalog | Eli Lilly | Sterile, aqueous, clear, and colorless solution | Subcutaneous and Intravenous infusion | Hypoglycemic Agents, Antidiabetic agents | Insulin receptor,Insulin-like growth factor 1 receptor |
1276 | Th1040 | Insulin Lispro | A chain:GIVEQCCTSICS Full view | 51 | Ia | Hormonal/Metabolic/genetic | Humalog KwikPen | Eli Lilly | Solution | Subcutaneous injection | Hypoglycemic Agents, Antidiabetic agents | Insulin receptor,Insulin-like growth factor 1 receptor |
1277 | Th1040 | Insulin Lispro | A chain:GIVEQCCTSICS Full view | 51 | Ia | Hormonal/Metabolic/genetic | Humalog Pen | Eli Lilly | N.A. | N.A. | Hypoglycemic Agents, Antidiabetic agents | Insulin receptor,Insulin-like growth factor 1 receptor |
1283 | Th1041 | Insulin Glargine | A-chain:GIVEQCCTSICS Full view | 53 | Ia | Hormonal/Metabolic/genetic | Lantus | Sanofi-Aventis | Solution | Subcutaneous injection | Hypoglycemic Agents, Antidiabetic agents | Insulin receptor,Insulin-like growth factor 1 receptor |
1284 | Th1041 | Insulin Glargine | A-chain:GIVEQCCTSICS Full view | 53 | Ia | Hormonal/Metabolic/genetic | Lantus OptiSet | N.A. | Solution | Subcutaneous injection | Hypoglycemic Agents, Antidiabetic agents | Insulin receptor,Insulin-like growth factor 1 receptor |
1285 | Th1041 | Insulin Glargine | A-chain:GIVEQCCTSICS Full view | 53 | Ia | Hormonal/Metabolic/genetic | Lantus SoloStar | N.A. | Solution | Subcutaneous injection | Hypoglycemic Agents, Antidiabetic agents | Insulin receptor,Insulin-like growth factor 1 receptor |
1372 | Th1055 | Follitropin beta | A Chain: APDVQDCPECT Full view | 204 | Ib | Hormonal disorders | Follistim AQ | Merck | Sterile aqueous solution | Subcutaneous or Intramuscular administration | Fertility Agents | Follicle-stimulating hormone receptor |
1375 | Th1056 | Vasopressin | CYFQNCPRG Full view | 9 | Ib | Hormonal | Pitressin | JHP Pharmaceuticals | Sterile, aqueous solution of synthetic vasopressin | Intramuscular or Subcutaneous use | Antidiuretic Agents | Vasopressin V2 receptor,Vasopressin V1a receptor,Vasopressin V1b receptor |
1382 | Th1060 | Insulin, porcine | A chain: GIVEQCCTSIC Full view | 51 | Ia | Hormonal/Metabolic | vetsulin | Intervet Inc (Merck Animal Health) | Sterile injectable suspension in multidose vials containing 10 mL of 40 IU/mL porcine insulin zinc suspension | Subcutaneous Injection | Hypoglycemic Agents | Interferon alpha/beta receptor 2,Interferon alpha/beta receptor 1, Hyaluronan, Transforming growth factor beta-1 |
1415 | Th1069 | Pegvisomant | FPTIPLSRLFDNAMLRAHRL Full view | 191 | IIa | Hormonal | SOMAVERT | Pfizer | Sterile, white lyophilized powder | Subcutaneous Injection | Hormone Replacement Agents | B-lymphocyte antigen CD20,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immunoglobulin gamma Fc region receptor III-A,High affinity immunoglobulin gamma Fc receptor I,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c |
1439 | Th1077 | Urofollitropin | Alpha chain:APDVQDCP Full view | 203 | Ib | Hormonal | BRAVELLE | Ferring Pharmaceuticals Inc. | Sterile, lyophilized powder used after reconstitution with sterile 0.9% Sodium Chloride Injection | Intramuscular and Subcutaneous administration | Fertility Agents | Glutamate carboxypeptidase 2 |
1440 | Th1077 | Urofollitropin | Alpha chain:APDVQDCP Full view | 203 | Ib | Hormonal | Metrodin | N.A. | Sterile, lypholized form contains an acidic, water soluble glycoprotein biologically standardized for FSH gonadotropin activity | Intramuscular injection. | Fertility Agents | Glutamate carboxypeptidase 2 |
1441 | Th1077 | Urofollitropin | Alpha chain:APDVQDCP Full view | 203 | Ib | Hormonal | Fertinex | N.A. | Sterile, lyophilized form contains an acidic, water soluble glycoprotein biologically standardized for FSH gonadotropin activity | Subcutaneous injection. | Fertility Agents | Glutamate carboxypeptidase 2 |
1447 | Th1080 | Choriogonadotropin Alfa | Alpha chain: APDVQDC Full view | 237 | Ib | Hormonal | Choriogonadotropin alfa | Emd serono inc, Ferring pharmaceuticals inc, App pharmaceuticals llc, Bel mar laboratories inc, Bris | N.A. | N.A. | Fertility Agents and Gonadotropins | Integrin alpha-L, Low affinity immunoglobulin gamma Fc region receptor III-B, Complement C1r subcomponent, Complement C1q subcomponent subunit A, Complement C1q subcomponent subunit B, Complement C1q subcomponent subunit C, Low affinity immunoglobulin gamma Fc region receptor III-A, High affinity immunoglobulin gamma Fc receptor I, Low affinity immunoglobulin gamma Fc region receptor II-a, Low affinity immunoglobulin gamma Fc region receptor II-b, Low affinity immunoglobulin gamma Fc region receptor II-c |
1460 | Th1087 | Oxytocin | CYIQNCPLG Full view | 9 | Ib | Hormonal | Pitocin | JHP Pharmaceuticals | Sterile, clear, colorless aqueous solution of synthetic oxytocin | Intravenous infusion | Oxytocics, Anti-tocolytic Agents and Labor Induction Agents | Interferon alpha/beta receptor 2,Interferon alpha/beta receptor 1, Globotriaosylceramide |
1478 | Th1098 | Exenatide | HGEGTFTSDLSKQMEEEAVR Full view | 39 | Ib | Hormonal/Metabolic | BYETTA | N.A. | N.A. | N.A. | Hypoglycemic Agents | Glucagon-like peptide 1 receptor |
1479 | Th1098 | Exenatide | HGEGTFTSDLSKQMEEEAVR Full view | 39 | Ib | Hormonal/Metabolic | BYDUREON | Amylin Pharmaceuticals | White to off-white powder that is available in a dosage strength of 2 mg exenatide per vial or per pen | N.A. | Hypoglycemic Agents | Glucagon-like peptide 1 receptor |
1480 | Th1099 | Mecasermin | GPETLCGAELVDALQFVCGD Full view | 70 | Ib | Hormonal | N.A. | N.A. | N.A. | N.A. | N.A. | Insulin-like growth factor 1 receptor,Insulin-like growth factor-binding protein 3,Insulin receptor,Cation-independent mannose-6-phosphate receptor |
1482 | Th1100 | Pramlintide | KCNTATCATQRLANFLVHSS Full view | 37 | Ia | Hormonal/Metabolic | Symlin | Amylin Pharmaceuticals (now a wholly owned subsidiary of AstraZeneca) | Clear, isotonic, sterile solution | Subcutaneous injection | N.A. | Calcitonin receptor,Receptor activity-modifying protein 1,Receptor activity-modifying protein 2,Receptor activity-modifying protein 3 |
1500 | Th1103 | Cosyntropin | ACTH(1-24): SYSM Full view | 24 | IV | Hormonal | Cortrosyn | Amphastar Pharmaceuticals | N.A. | Intravenous injection, Intravenous infusion, Intramuscular injection | Hormones and Diagnostic Agents | Adrenocorticotropic hormone receptor |
1501 | Th1104 | Corticotropin | SYSMEHFRWGKPVGKKRRPV Full view | 39 | IV | Hormonal | H.P. Acthar | Questcor Pharmaceuticals, Inc. | N.A. | N.A. | N.A. | N.A. |
1502 | Th1105 | Insulin Aspart | A chain: GIVEQCCTSIC Full view | 51 | Ia | Hormonal/Metabolic | NovoLog | Novo Nordisk | Sterile, aqueous, clear, and colorless solution | Subcutaneous injection, Intravenous injection | Hypoglycemic Agents and Antidiabetic Agents | Insulin receptor |
1503 | Th1105 | Insulin Aspart | A chain: GIVEQCCTSIC Full view | 51 | Ia | Hormonal/Metabolic | NovoLog Mix 50/50 | Novo Nordisk | Uniform, white, sterile suspension that contains insulin aspart | Subcutaneous injection | Hypoglycemic Agents and Antidiabetic Agents | Insulin receptor |
1504 | Th1105 | Insulin Aspart | A chain: GIVEQCCTSIC Full view | 51 | Ia | Hormonal/Metabolic | NovoLog Mix 70/30 | Novo Nordisk | Uniform, white, sterile suspension that contains insulin aspart 100 Units/mL. | Subcutaneous injection | Hypoglycemic Agents and Antidiabetic Agents | Insulin receptor |
1511 | Th1106 | Insulin Detemir | A chain: GIVEQCCTSIC Full view | 51 | Ia | Hormonal/Metabolic | LEVEMIR | Novo Nordisk | Clear, colorless, aqueous, neutral sterile solution | Subcutaneous injection | Antidiabetic Agents | Insulin receptor |
1520 | Th1107 | Insulin Glulisine | A chain: GIVEQCCTSIC Full view | 51 | Ib | Hormonal/Metabolic | APIDRA | sanofi-aventis | Sterile, aqueous, clear, and colorless solution | N.A. | Antidiabetic Agents | Insulin receptor |
1549 | Th1118 | Sulodexide | N.A. Full view | 0 | IIIc | Hormonal/genetic/Hematological/N.A. | SULODEXIDE | Syntex S.A | N.A. | N.A. | Antithrombins and Fibrinolytic Agents and Hypoglycemic Agents and Anticoagulants and Hypolipidemic Agents | Heparin cofactor 2,Antithrombin-III |
1576 | Th1124 | Liraglutide | HAEGTFTSDVSSYLEGQAAK Full view | 33 | Ib | Hormonal | Saxenda | Novo Nordisk | Clear, colorless solution | Subcutaneous injection | N.A. | Glucagon-like peptide 1 receptor |
1577 | Th1124 | Liraglutide | HAEGTFTSDVSSYLEGQAAK Full view | 33 | Ib | Hormonal | Victoza | Novo Nordisk | Clear, colorless solution. | Subcutaneous injection | N.A. | Glucagon-like peptide 1 receptor |
1600 | Th1127 | Buserelin | N.A. Full view | 0 | IIIc | Cancer/Hormonal | Suprecur (Nasal Spray Solution) | Sanofi-Aventis | 150 micrograms Nasal Spray Solution | Nasal spray | N.A. | Lutropin-choriogonadotropic hormone receptor,Gonadotropin-releasing hormone receptor |
1601 | Th1127 | Buserelin | pGlu-His-Trp-Ser-Tyr Full view | 9 | IIIc | Cancer/Hormonal | Suprecur (injection) | Sanofi-Aventis | 1mg/ml Injection | Subcutaneous injection | N.A. | Lutropin-choriogonadotropic hormone receptor,Gonadotropin-releasing hormone receptor |
1602 | Th1128 | Velaglucerase Alfa | ARPCIPKSFGYSSVVCVCNA Full view | 497 | Ia | Hormonal | VPRIV | Shire | Sterile, preservative free, lyophilized powder | Intravenous infusion | Enzymes | Glucosylceramidase |
1603 | Th1129 | Tesamorelin | YADAIFTNSYRKVLGQLSAR Full view | 44 | Ib | Hormonal | Egrifta | Theratechnologies | Sterile, white to off-white, preservative-free lyophilized powder | Subcutaneous injection | N.A. | Growth hormone-releasing hormone receptor |
1608 | Th1131 | Taliglucerase Alfa | EFARPCIPKSFGYSSVVCVC Full view | 504 | Ia | Hormonal | Elelyso | Pfizer | Sterile, non-pyrogenic, lyophilized product. | Intravenous infusion | Enzymes | Glucocerebroside |
1621 | Th1134 | Asparaginase Erwinia Chrysanthemi | ADKLPNIVILATGGTIAGSA Full view | 327 | Ic | Hormonal | Erwinaze | EUSA Pharma | Sterile, lyophilized, white powder in vials. | Intramuscular injection | Enzymes | N.A. |
1623 | Th1136 | Glucarpidase | ALAQKRDNVLFQAATDEQPA Full view | 393 | Ic | Hormonal | Voraxaze | BTG International | Sterile, preservative-free, white lyophilized powder in single-use vials | Intravenous injection | Enzymes | Methotrexate |
1634 | Th1140 | Insulin, Isophane Or Nph Insulin (Neutral Protamine Hagedorn) | A chain: GIVEQCCTSIC Full view | 51 | Ia | Hormonal/Metabolic | Novolin N | Novo Nordisk | Novolin N InnoLet (nph, human insulin isophane suspension 3 ml disposable prefilled syringe) | Subcutaneous injection | Hypoglycemic Agents and Antidiabetic Agents | Insulin receptor |
1638 | Th1144 | Follitropin Alpha | N.A. Full view | 0 | Ib | Adjunct therapy/ Hormonal | Gonal-F | Serono Laboratories | Sterile, lyophilized powder. | Subcutaneous injection | N.A. | N.A. |
1639 | Th1144 | Follitropin Alpha | N.A. Full view | 0 | Ib | Adjunct therapy/ Hormonal | Gonal-f RFF | EMD SERONO | Sterile, lyophilized powde | Subcutaneous injection | N.A. | N.A. |
1655 | Th1151 | Somatotropin Recombinant | FPTIPLSRLFDNAMLRAHRL Full view | 192 | Ib | Hormonal/Metabolic | NutropinAQ | Genentech Inc. | Sterile, white lyophilized powder intended for subcutaneous administration after reconstitution with Bacteriostatic Water | Subcutaneous administration | Hormone Replacement Agents | Growth hormone receptor, Prolactin receptor |
1656 | Th1151 | Somatotropin Recombinant | FPTIPLSRLFDNAMLRAHRL Full view | 192 | Ib | Hormonal/Metabolic | BioTropin | Bio-Technology General (Israel) Ltd. | Sterile, white, lyophilized powder | Subcutaneous administration | Hormone Replacement Agents | Growth hormone receptor, Prolactin receptor |