==== Reference: Usmani SS, Bedi G, Samuel JS, Singh S, Kalra S, Kumar P, et al. (2017) THPdb: Database of FDA-approved peptide and protein therapeutics. PLoS ONE 12(7) e0181748.====

Browse result page of THPdb

The total number entries retrieved from this search are 53
IDThPPIDNamePeptide SequenceLengthFunctional ClassificationDiseaseBrandCompanyPhysical AppearanceRoute of AdministartionCategoryTarget
1361Th1051Human Serum AlbuminMKWVTFISLLFLFSSAYSRG Full view609IaHematological/Metabolic/geneticAlbuminarCSL BehringSterile aqueous solution of albumin obtained from large pools of adult human venous plasma by low temperature controlled fractionation according to the Cohn process.Albumin (Human) 25%, Albuminar-25 (albumin human) , is to be administered by the Intravenous route.Serum substitutes N.A.
1362Th1051Human Serum AlbuminMKWVTFISLLFLFSSAYSRG Full view609IaHematological/Metabolic/geneticAlbuteinGRIFOLSSterile, aqueous solution for single dose intravenous administration containing 20% human albumin (weight/volume).Albutein 20% is to be administered by the Intravenous route.Serum substitutes N.A.
1365Th1053Serum albumin iodonatedMKWVTFISLLFLFSSAYSRG Full view600IVHematological DisordersMegatopeIsoTex DiagnosticsColorless to very pale yellow solutionsInjection for Intravenous administrationDiagnostic Agents Apolipoprotein E,Serum amyloid A-1 protein,Protein AMBP
1366Th1053Serum albumin iodonatedMKWVTFISLLFLFSSAYSRG Full view600IVHematological DisordersJeanotopeIsoTex DiagnosticsSterile, nonpyrogenic, aqueos solutionIntravenous infusionDiagnostic Agents Apolipoprotein E,Serum amyloid A-1 protein,Protein AMBP
1367Th1053Serum albumin iodonatedMKWVTFISLLFLFSSAYSRG Full view600IVHematological DisordersVolumexIsoTex DiagnosticsColorless to very pale yellow.Intravenous infusionDiagnostic Agents Apolipoprotein E,Serum amyloid A-1 protein,Protein AMBP
1381Th1059HyaluronidaseMWTGLGPAVTLALVLVVAWA Full view476IcAdjunct TherapyHYLENEXBaxter Healthcare CorporationSterile, clear, colorless, nonpreserved, ready for use solution.Human Injection Subcutaneous useAdjuvants, Anesthesia and Permeabilizing Agents N.A.
1389Th1062RituximabHeavy Chain: QVQLQQP Full view664IIaCancer/ImmunologicalRituxanBiogen Idec Inc., and Genentech USA, IncSterile, clear, colorless, preservative-free liquid concentrate Intravenous administrationAntineoplastic Agents, Immunologic Factors and Antirheumatic Agents B-lymphocyte antigen CD20,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immunoglobulin gamma Fc region receptor III-A,Complement C1s subcomponent,High affinity immunoglobulin gamma Fc receptor I,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c, Receptor tyrosine-protein kinase erbB-2,Epidermal growth factor receptor,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Complement C1s subcomponent,High affinity immunoglobulin gamma Fc receptor I,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor I
1398Th1063BasiliximabHeavy Chain: QLQQSGT Full view657IIaImmunologicalSimulectNovartisSterile lyophilisate which is available in 6 mL colorless glass vials and is available in 10 mg and 20 mg strengthintravenous infusion mainly or bolus (if no allergic reactions occurs)Immunosuppressive Agents N.A.
1400Th1064MuromonabHeavy Chain: QVQLQQS Full view664IIaImmunologicalORTHOCLONE OKT3 STERILE SOLUTIONCentocor Ortho Biotech, L.P.Sterile Solution is a murine monoclonal antibody to the CD3 antigen of human T cells which functions as an immunosuppressant.For Intravenous Use OnlyImmunologic Factors and Immunosuppressive Agents N.A.
1403Th1065Digoxin Immune Fab (Ovine)Heavy Chain: EVQLQQS Full view438IIaCardiacDIGIBINDGalaxo Smith KlineSterile lyophilized powder of antigen binding fragments (Fab) derived from specific antidigoxin antibodies raised in sheep.Intravenous infusion after reconstitution with Sterile Water for InjectionAntidotes T-cell surface glycoprotein CD3 delta chain, T-cell surface glycoprotein CD3 epsilon chain, T-cell surface glycoprotein CD3 gamma chain, T-cell surface glycoprotein CD3 zeta chain, Low affinity immunoglobulin gamma Fc region receptor III-B, Complement C1r subcomponent, Complement C1q subcomponent subunit A, Complement C1q subcomponent subunit B, Complement C1q subcomponent subunit C, Low affinity immunoglobulin gamma Fc region receptor III-A, Complement C1s subcomponent, High affinity immunoglobulin gamma Fc receptor I, Low affinity immunoglobulin gamma Fc region receptor II-a, Low affinity immunoglobulin gamma Fc region receptor II-b, Low affinity immunoglobulin gamma Fc region receptor II-c
1404Th1065Digoxin Immune Fab (Ovine)Heavy Chain: EVQLQQS Full view438IIaCardiacDigiFab Protherics IncSterile, purified, lyophilized preparation of digoxin-immune ovine Fab (monovalent) immunoglobulin fragments. Intravenous administration Antidotes T-cell surface glycoprotein CD3 delta chain, T-cell surface glycoprotein CD3 epsilon chain, T-cell surface glycoprotein CD3 gamma chain, T-cell surface glycoprotein CD3 zeta chain, Low affinity immunoglobulin gamma Fc region receptor III-B, Complement C1r subcomponent, Complement C1q subcomponent subunit A, Complement C1q subcomponent subunit B, Complement C1q subcomponent subunit C, Low affinity immunoglobulin gamma Fc region receptor III-A, Complement C1s subcomponent, High affinity immunoglobulin gamma Fc receptor I, Low affinity immunoglobulin gamma Fc region receptor II-a, Low affinity immunoglobulin gamma Fc region receptor II-b, Low affinity immunoglobulin gamma Fc region receptor II-c
1406Th1066IbritumomabHeavy Chain: QAYLQQS Full view652IIbCancerZevalinSpectrum PharmaceuticalsClear, colorless, sterile, pyrogen-free, preservative-free solution that may contain translucent particles.Intravenous infusionN.A. Digoxin
1428Th1072StreptokinaseMKNYLSFGMFALLFALTFGT Full view440IcMetabolic/HaemetologicalStreptaseCSL BehringSterile, purified preparation formulated as lypholized powderIntravenous and intracoronary administration.Fibrinolytic Agents and Thrombolytic Agents N.A.
1434Th1074AlgluceraseARPCIPKSFGYSSVVCVCNA Full view497IaMetabolicCeredaseGenzyme CorporationClear sterile non-pyrogenic solution of alglucerase in a citrate buffered solutionIntravenous injectionEnzyme Replacement Agents Plasminogen,Proteinase-activated receptor 1
1437Th1076LaronidaseAPHLVQVDAARALWPLRRFW Full view626IaMetabolicALDURAZYMEGenzyme CorporationSterile, nonpyrogenic, colorless to pale yellow, clear to slightly opalescent solution that must be diluted prior to administration in 0.9% Sodium Chloride InjectionIntravenous infusionEnzyme Replacement Agents N.A.
1445Th1079Serum AlbuminDAHKSEVAHRFKDLGEENFK Full view585IVMetabolic/geneticAlbunexMallinckrodt; Tyco HealthcareN.A.Intravenous infusionSerum substitutes N.A.
1446Th1079Serum AlbuminDAHKSEVAHRFKDLGEENFK Full view585IVMetabolic/geneticOptisonGE HealthcareN.A.Intravenous infusionSerum substitutes N.A.
1453Th1083Coagulation Factor IxYNSGKLEEFVQGNLERECME Full view415IaHematological/Metabolic/geneticAlprolixBiogen Idec Inc., and Genentech USA, IncSterile, non-pyrogenic, preservative-free, white to off-white, lyophilized powder to cake for reconstitution with the provided diluentIntravenous infusionCoagulants and Thrombotic Agents N.A.
1466Th1090DaclizumabQVQLVQSGAEVKKPGSSVKV Full view674IIaImmunologicalsZenapaxRocheClear, sterile, colorless concentrate for further dilution and intravenous administrationIntravenous injectionImmunosuppressive Agents Fusion glycoprotein F0,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immunoglobulin gamma Fc region receptor III-A,High affinity immunoglobulin gamma Fc receptor I,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c
1475Th1095RanibizumabLight Chain SASQDISN Full view447IIaHematological/Eye DisorderLucentisGenentechSterile, colorless to pale yellow solutionIntravitreal injectionOphthalmics Vascular endothelial growth factor A
1476Th1096IdursulfaseSETQANSTTDALNVLLIIVD Full view525IaMetabolicElapraseSHIRESterile, nonpyrogenic clear to slightly opalescent, colorless solution that must be diluted prior to administration in 0.9% Sodium Chloride Injection, USPIntravenous infusionEnzyme Replacement Agents Dermatan sulfate,Heparan sulfate,Perilipin-3
1494Th1101GalsulfaseSGAGASRPPHLVFLLADDLG Full view497IaMetabolicNaglazymeBioMarinSterile, nonpyrogenic, colorless to pale yellow, clear to slightly opalescent solution that must be diluted with 0.9% Sodium Chloride Injection, USP, prior to administrationIntravenous infusionEnzyme Replacement Agents Dermatan sulfate,Perilipin-3
1548Th1117IpilimumabHeavy chain: QVQLVES Full view663IIIcCancerYERVOYBristol-Myers SquibbSterile, preservative-free, clear to slightly opalescent, colorless to pale-yellow solutionN.A.Antineoplastic Agents and Monoclonal antibodies Cytotoxic T-lymphocyte protein 4
1560Th1121Pertuzumablight chain DIQMTQSP Full view664IIIcCancerPerjetaGenentechSterile, clear to slightly opalescent, colorless to pale brown liquidIntravenous infusionMonoclonal antibodies Receptor tyrosine-protein kinase erbB-2
1570Th1123DenosumabHeavy chain EVQLLESG Full view664IIIcOsteologicalXgevaAmgen.Sterile, preservative-free, clear, colorless to pale yellow solutionN.A.Bone Density Conservation Agents and Monoclonal antibodies Tumor necrosis factor ligand superfamily member 11
1571Th1123DenosumabHeavy chain EVQLLESG Full view664IIIcOsteologicalProliaAmgen.Sterile, preservative-free, clear, colorless to pale yellow solutionN.A.Bone Density Conservation Agents and Monoclonal antibodies Tumor necrosis factor ligand superfamily member 11
1602Th1128Velaglucerase AlfaARPCIPKSFGYSSVVCVCNA Full view497IaHormonalVPRIVShireSterile, preservative free, lyophilized powderIntravenous infusionEnzymes Glucosylceramidase
1604Th1130Brentuximab VedotinHeavy chain:QIQLQQSG Full view664IIbCancerAdcetrisSeattle GeneticsSterile, white to off-white, preservative-free lyophilized cake or powder in single-use vials.Intravenous infusionN.A. Tumor necrosis factor receptor superfamily member 8
1608Th1131Taliglucerase AlfaEFARPCIPKSFGYSSVVCVC Full view504IaHormonalElelysoPfizerSterile, non-pyrogenic, lyophilized product.Intravenous infusionEnzymes Glucocerebroside
1615Th1133AfliberceptSDTGRPFVEMYSEIPEIIHM Full view431IbCancerEyleaRegeneron PharmaceuticalsSterile, clear, and colorless to pale yellow solution.Intravitreal injectionAntineoplastic Agents and Ophthalmics Vascular endothelial growth factor A,Placenta growth factor,Vascular endothelial growth factor B
1616Th1133AfliberceptSDTGRPFVEMYSEIPEIIHM Full view431IbCancerZaltrapSanofi and Regeneron Pharmaceuticals, Inc.Sterile, clear, colorless to pale yellow, non-pyrogenic, preservative-free, solution.Intravenous infusionAntineoplastic Agents and Ophthalmics Vascular endothelial growth factor A,Placenta growth factor,Vascular endothelial growth factor B
1628Th1139Certolizumab PegolLight chain: DIQMTQS Full view443IIbImmunologcalCimziaUCBSterile, white, lyophilized powder for solution or as a sterile, solution in a single-use prefilled 1 mL glass syringeSubcutaneous injectionTNF inhibitor Tumor necrosis factor
1637Th1143Fibrinolysin Aka PlasminFibrinolysin heavy c Full view786IcHematologicalElaseN.A.N.A.N.A.N.A. N.A.
1654Th1150SecukinumabSecukinumab Heavy Ch Full view672IIaImmunologicalCosentyxNovartis Pharmaceuticals CorporationSterile, preservative-free, clear to slightly opalescent, colorless to slightly yellow solution.Subcutaneous injectionInhibitor IL-17A cytokine
1659Th1152Drotrecogin alfaHeavy Chain: LIDGKMT Full view402IbInfectiousXigrisEli Lilly and CompanySterile, lyophilized, white to off-white powderIntravenous InfusionAntisepsis Coagulation factor VIII, V, Plasminogen activator inhibitor 1, Thrombomodulin, Vitamin K-dependent protein S, Ceruloplasmin, Prothrombin, Platelet factor 4, Plasma serine protease inhibitor, Serpin B6, Vitamin K-dependent gamma-carboxylase, Endothelial protein C receptor
1661Th1153AlefaceptHeavy Chain: CFSQQIY Full view705IIaImmunologicalAmeviveAstellas Pharma Inc.Sterile, white-to-off-white, preservative-free, lyophilized powderIntramuscular InjectionDermatologic and Immunosupressive agents T-cell surface antigen CD2, Complement C1r subcomponent, Complement C1q subcomponent subunit A, B, C, Low affinity immunoglobulin gamma Fc region receptor III-A,III-B, II-a, II-b, II-c
1671Th1159Gemtuzumab ozogamicinLight Chain 1: QIVLT Full view459IIbCancerMylotargWyeth pharmaceuticals incSterile, white, preservative-free lyophilized powderIntravenous infusionAntineoplastic agents and Immunotoxins Myeloid cell surface antigen CD33, Low affinity immunoglobulin gamma Fc region receptor III-B, Complement C1r subcomponent, Complement C1q subcomponent subunit A, Complement C1q subcomponent subunit B, Complement C1q subcomponent subunit C, Low affinity immunoglobulin gamma Fc region receptor III-A, Complement C1s subcomponent, High affinity immunoglobulin gamma Fc receptor I, Low affinity immunoglobulin gamma Fc region receptor II-a, Low affinity immunoglobulin gamma Fc region receptor II-b, Low affinity immunoglobulin gamma Fc region receptor II-c
1674Th1161AlbiglutideHGEGTFTSDVSSYLEGQAAK Full view645IbHormonal disordersEperzanGlaxosmithkline IncPowder for SolutionSubcutaneousDrugs used in diabetes; alimentary tract and metabolism; blood glucose lowering drugs, excl. insulins. Glucagon-like peptide 1 receptor
1676Th1161AlbiglutideHGEGTFTSDVSSYLEGQAAK Full view645IbHormonal disordersTanzeumGlaxo Smith Kline LlcInjection, Powder, Lyophilized, for SolutionSubcutaneousDrugs used in diabetes; alimentary tract and metabolism; blood glucose lowering drugs, excl. insulins. Glucagon-like peptide 1 receptor
1694Th1166Asfotase AlfaLVPEKEKDPKYWRDQAQETL Full view726IaGenetic DisordersStrensiqAlexion Pharma GhbhSolutionSubcutaneousEnzymes Alimentary Tract and Metabolism Sphingosine 1-phosphate receptor 1; Pyrophosphate
1695Th1166Asfotase AlfaLVPEKEKDPKYWRDQAQETL Full view726IaGenetic DisordersStrensiqAlexion Pharmaceuticals Inc.SolutionSubcutaneousEnzymes Alimentary Tract and Metabolism Sphingosine 1-phosphate receptor 1; Pyrophosphate
1708Th1170BlinatumomabDIQLTQSPASLAVSLGQRAT Full view504IIIcCancer/GeneticBlincytoAMGENLyophilized Powder for intravenous administrationIntravenousAntineoplastic Agents, Immunosuppressive Agents, Monoclonal antibodies, Antineoplastic and Immunomodulating Agents B-lymphocyte antigen CD19; T-cell surface glycoprotein CD3 delta chain
1736Th1177Elosulfase alfaAPQPPNILLLLMDDMGWGDL Full view496IaMetabolic DisordersVimizimBiomarin International LimitedSolutionIntravenousEnzymes; Alimentary Tract and Metabolism N-acetylgalactosamine-6-sulfatase
1738Th1178Elotuzumabheavy chain EVQLVESG Full view689IIIcCancerNANAInjection, Powder, Lyophilized, for SolutionIntravenousNA SLAM family member 7
1739Th1178Elotuzumabheavy chain EVQLVESG Full view689IIIcCancerEmplicitiE.R. Squibb & Sons, L.L.C.Powder Lyophilized for SolutionIntravenousNA SLAM family member 8
1740Th1178Elotuzumabheavy chain EVQLVESG Full view689IIIcCancerEmplicitiE.R. Squibb & Sons, L.L.C.Powder Lyophilized for SolutionIntravenousNA SLAM family member 9
1797Th1191VedolizumabHeavy Chain Sequence Full view716IIaImmunological DisordersEntyvioTakeda Pharmaceuticals America, Inc.Injection, Powder, Lyophilized, for SolutionIntravenousImmunosupressive agent, Antineoplastic agent Integrin alpha-4, Integrin beta-7
1802Th1196SiltuximabHeavy Chain Sequence Full view708IIaImmunological DisordersSylvantJanssen IncLyophilized PowderIntravenous infusionAntineoplastic and Immunomodulating Agents, Immunosuppressive Agents Interleukin-6
1811Th1202PembrolizumabHeavy Chain Sequence Full view711IIIcCancerKeytrudaMerck Sharp & Dohme Corp.Lyophilized PowderIntravenous infusionAntineoplastic and Immunomodulating Agents Programmed cell death protein 1
1813Th1204OfatumumabOfatumumab Heavy Cha Full view483IIIcCancerArzerraGlaxo Smith Kline LlcLiquidIntravenousAntineoplastic and Immunomodulating Agents