Welcome to Entry Card of Peptide


Details of TopicalPdb ID 1091

PRIMARY INFORMATION
ID1091
PMID22189681
Year2011
SequenceRKKRRQRRR
NameTat
Length9
N-Terminal ModificationFree
C-Terminal ModificationFree
Linear/ CyclicLinear
ChiralityL
Chemical ModificationNone
Origin of PeptideHIV-1
Nature of Peptide/CargoTat-SOD is anti-inflammatory
MechanismTat-SOD slightly suppressed COX-2, IL-6 and IL-1β expression
Cargo Sequence/StructureNot available
Name of cargo
SOD
AssayHistochemical analysis
EnhancerNone
Properties of enhancerNot applicable
Concentration2µg/ear of mice
Incubation time4 days
Tissue permeability (value with units)Significant permeability of the Tat-SOD peptide can be seen in histochemical images
Tissue SampleEar of mice
Ex vivo/In vivo/In vitroin vivo
SECONDARY INFORMATION
STRUCTURE
Predicted Structure
SMILESN[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H]
(CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N
[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)
C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC
(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])
N)C(=O)N[C@@H](CCCNC(=[NH2])N)C=O