Welcome to Entry Card of Peptide


Details of TopicalPdb ID 1590

PRIMARY INFORMATION
ID1590
PMID25786877
Year2013
SequenceAW
NameAlanine-tryptophan
Length2
N-Terminal ModificationFree
C-Terminal ModificationFree
Linear/ CyclicLinear
ChiralityL
Chemical ModificationNone
Origin of PeptideSynthetic
Nature of Peptide/CargoNot mentioned
MechanismNot mentioned
Cargo Sequence/StructureNone
Name of cargo
Not applicable
Assayelectroosmotic volume flux was observed to study peptide penetration
EnhancerThe donor solution pH was maintained at physiological pH 7.4 or at pH levels 6.0, 5.5, 5.0 and 3 using 0.1 or 0.01 M sodium hydroxide (NaOH) and/or 0.1 or 0.01 M hydrochloric acid (HCl) solutions.
Properties of enhancerNot mentioned
Concentration1-10 mg/ml
Incubation timeNot mentioned
Tissue permeability (value with units)Skin permeability of peptide increased 30 times more than passive permeation.
Tissue SampleHuman epidermal membrane
Ex vivo/In vivo/In vitroin vitro
SECONDARY INFORMATION
STRUCTURE
Predicted Structure
SMILESN[C@@H](C)C(=O)N[C@@H](Cc1c
[nH]c2ccccc12)C=O