Welcome to Entry Card of Peptide


Details of TopicalPdb ID 1615

PRIMARY INFORMATION
ID1615
PMID25041740
Year2014
SequenceLLGDFFRKSKEKIGK
EFKRIVQRIKDFLRN
LVPRTES
NameLL-37
Length37
N-Terminal ModificationFree
C-Terminal ModificationFree
Linear/ CyclicLinear
ChiralityL
Chemical ModificationNone
Origin of PeptideSynthetic
Nature of Peptide/CargoNot mentioned
MechanismNot well understood
Cargo Sequence/StructureNone
Name of cargo
Not applicable
AssayStatistical analysis was done in order to measure the efficacy of LL-37 as a drug.
EnhancerNone
Properties of enhancerNot applicable
Concentration1.6mg/ml
Incubation time4 weeks
Tissue permeability (value with units)The ulcers decreased to 50%
Tissue SampleHuman skin
Ex vivo/In vivo/In vitroin vitro
SECONDARY INFORMATION
STRUCTURE
Predicted Structure
SMILESN[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N
[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C
(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H]
(C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H]
(C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H]
(C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N
[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)
N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C
(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H]
(C(=O)N[C@H](C(=O)N[C@H](C=O)CO)CCC(=O)O)
[C@H](O)C)CCCNC(=N)N)CCC)C(C)C)CC
(C)C)CC(=O)N)CCCNC(=N)N)CC(C)C)Cc1
ccccc1)CC(=O)O)CCCCN)[C@H](CC)C)CCCNC(=N)N)
CCC(=O)N)C(C)C)[C@H](CC)C)CCCNC(=N)N)CCCCN)
Cc1ccccc1)CCC(=O)O)CCCCN)[C@H](CC)C)CCCCN)
CCC(=O)O)CCCCN)CO)CCCCN)CCCNC(=N)N)Cc1ccccc1)
Cc1ccccc1)CC(=O)O)CC(C)C)CC(C)C