BioPhytMol: A database of Phytomolecules against Mycobacteria

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Page - 1 of 4 Record - 1 of 82 [TOP]

Compound ID	1033
Compound Structure
Plant Source	Achillea millefolium L. Common Name:Yarrow (English), Brinjasipha (Sanskrit)
Source Family	Asteraceae (Compositae)
Origin	Mexico, India
Plant Part Used	Flower, leaf
Extract	Water
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done	Broth Dilution Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)	< 1:20 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified	N/A
PubChem ID	NR
Ethnomedicinal Information	Cough, tuberculosis, colds, flu, fever, astringent
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34
Curator

Record - 2 of 82 [TOP]

Compound ID

1056

Compound Structure

Plant Source

Adhatoda vasica Nees Common Name:Malabar Nut Tree (English), Vasaka (Sanskrit)

Source Family

Acanthaceae

Origin

India

Plant Part Used

Leaf

Extract

Target Bacteria

Mycobacterium tuberculosis

Assay / Test Done

Broth Dilution Assay

Positive Control Used (conc.)

Inhibition [%]

Activity [MIC] µg/ml

128 µg/ml

Activity (In terms of dilution)

Activity (Zone of inhibition in mm)

Active Compound Identified

Bromhexine

PubChem ID

2442

Ethnomedicinal Information

Treatment of tuberculosis, asthma and also as expectorants, bronchial disorders such as acute and chronic cough, bronchitis

PubMed ID [Source Literature]

8778507

Extract Preparation

N/A

Chemical Classification [Active Compound]

Aromatic, Cyclohexane, Amine, Haloginated

Media / Broth Used [Antimicrobial Assay/Test]

N/A

Cytotoxicity Assay [AID]

N/A

Molecular Weight

373.999

Molecular Formula

C₁₄H₂₀Br₂N₂

SMILES

Brc1c(N)c(CN(C2CCCCC2)C)cc(Br)c1

XLogP

4.004

PSA

29.260

H-bond Donor

H-bond Acceptor

No. of Rotatable Bond Count

No. of Rings

No. of N

No. of O

No. of S

Reference(s)

1) Grange JM, Snell NJ.Activity of bromhexine and ambroxol, semi-synthetic derivatives of vasicine from the Indian shrub Adhatoda vasica, against Mycobacterium tuberculosis in vitro.J Ethnopharmacol. 1996 Jan;50(1):49-53

Curator

Record - 3 of 82 [TOP]

Compound ID

1057

Compound Structure

Plant Source

Adhatoda vasica Nees Common Name:Malabar Nut Tree (English), Vasaka (Sanskrit)

Source Family

Acanthaceae

Origin

India

Plant Part Used

Leaf

Extract

Target Bacteria

Mycobacterium tuberculosis

Assay / Test Done

Broth Dilution Assay

Positive Control Used (conc.)

Inhibition [%]

Activity [MIC] µg/ml

64 µg/ml

Activity (In terms of dilution)

Activity (Zone of inhibition in mm)

Active Compound Identified

Ambroxol

PubChem ID

2132

Ethnomedicinal Information

Treatment of tuberculosis, asthma and also as expectorants, bronchial disorders such as acute and chronic cough, bronchitis

PubMed ID [Source Literature]

8778507

Extract Preparation

N/A

Chemical Classification [Active Compound]

Aromatic, Cyclohexane, Amine, Haloginated, Alcohol

Media / Broth Used [Antimicrobial Assay/Test]

N/A

Cytotoxicity Assay [AID]

N/A

Molecular Weight

375.979

Molecular Formula

C₁₃H₁₈Br₂N₂O

SMILES

Brc1c(N)c(CNC2CCC(O)CC2)cc(Br)c1

XLogP

2.524

PSA

58.280

H-bond Donor

H-bond Acceptor

No. of Rotatable Bond Count

No. of Rings

No. of N

No. of O

No. of S

Reference(s)

Curator

Record - 4 of 82 [TOP]

Compound ID	1099
Compound Structure
Plant Source	Allium sativum L. Common Name:Garlic (English), Lashuna (Sanskrit)
Source Family	Liliaceae
Origin	India, Africa, Malaysia
Plant Part Used	Leaf
Extract	Water
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done	Broth Dilution Assay
Positive Control Used (conc.)
Inhibition [%]	100 %
Activity [MIC] µg/ml
Activity (In terms of dilution)	1:640 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Bronchitis, asthma, expectorant, cough, pulmonary phthisis, consumption, chronic diseases of lungs, whooping cough, laryngeal tuberculosis
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34
Curator

Record - 5 of 82 [TOP]

Compound ID	1199
Compound Structure
Plant Source	Apium graveolens L. Common Name:Celery (English), Ajmodaa, Ajmoda, Ajmodikaa, Dipyaka (Sanskrit)
Source Family	Apiaceae (Umbelliferae)
Origin	India
Plant Part Used	Leaf
Extract	Water
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done	Broth Dilution Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)	1:40 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Bronchitis, asthma, chest pain, cough, anthelmintic, antifungal, fever, urinary calculi, obesity, musculoskeletal disorder, dropsy, chronic diarrhoea
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34 2) http://parisaramahiti.kar.nic.in/Medicinal_plants_new/med%20plants/p18.html
Curator

Record - 6 of 82 [TOP]

Compound ID	1223
Compound Structure
Plant Source	Asparagus officinalis L Common Name:Asparagus, Sparrow grass (English), Shataavari, Vari (Sanskrit)
Source Family	Liliaceae
Origin	India
Plant Part Used	Leaf
Extract	Water
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done	Broth Dilution Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)	< 1:20 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Diuretic, laxative, jaundice, rheumatism, cardiac disorders
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34 2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 1–4. Lalit Mohan Basu, Allahabad, India
Curator

Record - 7 of 82 [TOP]

Compound ID	1231
Compound Structure
Plant Source	Azadirachta indica A.juss. Common Name:Neem Tree, Margosa Tree (English), Nimba, Nimbaka (Sanskrit)
Source Family	Meliaceae
Origin	India, Kenya
Plant Part Used	Stem bark
Extract	Methanol
Target Bacteria	Mycobacterium tuberculosis, Mycobacterium avian, Mycobacterium chelonae, Mycobacterium intracellulare, Mycobacterium tarrae
Assay / Test Done	Broth Dilution Assay
Positive Control Used (conc.)
Inhibition [%]	10 %
Activity [MIC] µg/ml	8000 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Cough, asthma, consumption, phthisis, tuberculosis, anthelmintic, antiseptic. Used to treat chronic leprosy, skin diseases, intestinal worms, chronic malaria fevers, small pox, syphylictic sores
PubMed ID [Source Literature]	9533435
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Fabry W, Okemo PO, Ansorg R.Antibacterial activity of East African medicinal plants.J Ethnopharmacol. 1998 Feb;60(1):79-84
Curator

Record - 8 of 82 [TOP]

Compound ID	1248
Compound Structure
Plant Source	Berberis vulgaris L. Common Name:Common Barberry, True Barberry (English), Daruharidraa (Sanskrit)
Source Family	Berberidaceae
Origin	India
Plant Part Used	Leaf
Extract	Water
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done	Broth Dilution Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)	1:40 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	General infectious diseases, antiseptic, disinfectant
PubMed ID [Source Literature]	20571171
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gupta R, Thakur B, Singh P, Singh HB, Sharma VD, Katoch VM, Chauhan SV.Anti-tuberculosis activity of selected medicinal plants against multi-drug resistant Mycobacterium tuberculosis isolates.Indian J Med Res. 2010 Jun;131:809-13
Curator

Record - 9 of 82 [TOP]

Compound ID	1255
Compound Structure
Plant Source	Beta vulgaris L. Common Name:Beet Root, Garden Beet, Chard (English), Palanki (Sanskrit)
Source Family	Chenopodiaceae
Origin	India
Plant Part Used	Leaf
Extract	Water
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done	Broth Dilution Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)	< 1:20 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Expectorant, diuretic, cooling, diaphoretic, burns, diseases of spleen and liver, aphrodisiac, inflammations
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34
Curator

Record - 10 of 82 [TOP]

Compound ID	1288
Compound Structure
Plant Source	Brassica nigra (L.) Koch. Common Name:Black Mustard (English), Banarasi Raai, Raajika (Sanskrit)
Source Family	Brassicaceae
Origin	India
Plant Part Used	Flower, leaf
Extract	Water
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done	Broth Dilution Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)	< 1:40 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Leprosy, cough, sore throat
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34 2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 1–4. Lalit Mohan Basu, Allahabad, India
Curator

Record - 11 of 82 [TOP]

Compound ID	1307
Compound Structure
Plant Source	Buxus papillosa C. K. syn. Buxus sempervirens L. Common Name:Himalayan Boxwood Tree (English)
Source Family	Buxaceae
Origin	India
Plant Part Used	Leaf
Extract	Water
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done	Broth Dilution Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)	1:320 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Combs, pain, headache, stomatitis, febrifuge, syphilis, rheumatism, diaphoretic, random screening
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34 2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 1–4. Lalit Mohan Basu, Allahabad, India
Curator

Record - 12 of 82 [TOP]

Compound ID	1308
Compound Structure
Plant Source	Buxus papillosa C. K. syn. Buxus sempervirens L. Common Name:Himalayan Boxwood Tree (English)
Source Family	Buxaceae
Origin	India
Plant Part Used	Wood
Extract	Water
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done	Broth Dilution Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)	1:80 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Combs, pain, headache, stomatitis, febrifuge, syphilis, rheumatism, diaphoretic, random screening
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34 2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 14. Lalit Mohan Basu, Allahabad, India
Curator

Record - 13 of 82 [TOP]

Compound ID	1434
Compound Structure
Plant Source	Chenopodium album L. Common Name:Fat Hen (English), Vaastuuka (Sanskrit)
Source Family	Chenopodiaceae
Origin	India
Plant Part Used	Leaf
Extract	Water
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done	Broth Dilution Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)	< 1:20 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Throat problems, skin diseases, urinary complaints, laxative, anthelmintic, diuretic, aphrodisiac, abdominal pain
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34 2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 14. Lalit Mohan Basu, Allahabad, India
Curator

Record - 14 of 82 [TOP]

Compound ID	1446
Compound Structure
Plant Source	Cichorium intybus L. Common Name:Chicory, Indian Endive (English), Kaasani (Sanskrit)
Source Family	Asteraceae (Compositae)
Origin	India
Plant Part Used	Leaf
Extract	Water
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done	Broth Dilution Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)	< 1:20 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Asthma
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34 2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 14. Lalit Mohan Basu, Allahabad, India
Curator

Record - 15 of 82 [TOP]

Compound ID	1452
Compound Structure
Plant Source	Cinnamomum zeylanicum Breyn. Common Name:Cinnamon, Ceylon Cinnamon (English),Tvak, Daaruchini (Sanskrit)
Source Family	Lauraceae
Origin	Sri Lanka, Sumatra, Eastern Islands, Brazil, Mauritius, India, Jamaica
Plant Part Used	Leaf
Extract	Water
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done	Broth Dilution Assay
Positive Control Used (conc.)
Inhibition [%]	100 %
Activity [MIC] µg/ml	1:640 dilution
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Antiseptic and used to treat gonorrhoea, asthma, diabetes, diseases of oral cavity, bronchitis, expectorant
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34 2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 14. Lalit Mohan Basu, Allahabad, India
Curator

Record - 16 of 82 [TOP]

Compound ID	1530
Compound Structure
Plant Source	Convolvulus arvensis L. Common Name:Deers Foot (English), Bhadrabalaa, Hiranpadi (Sanskrit)
Source Family	Convolvulaceae
Origin	India
Plant Part Used	Leaf
Extract	Water
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done	Broth Dilution Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml	1:40 dilution
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Fever, purgative, cathartic, Random screening
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34 2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 14. Lalit Mohan Basu, Allahabad, India
Curator

Record - 17 of 82 [TOP]

Compound ID	1568
Compound Structure
Plant Source	Cucumis muricatus Wall. syn. Cucumis sativus L. Common Name:Cucumber (English), Trapusha, Trapushi, Tiktakarkatikaa (Sanskrit)
Source Family	Cucurbitaceae
Origin	India
Plant Part Used	Fruit
Extract	Water
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done	Broth Dilution Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml	< 1:40 dilution
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Whooping cough
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34 2) Megoneisto, Rao, R.R., 1983. Ethnobotanical studies in Nagaland-4. Sixty two medicinal plants used by the Angami Nagas. Journal of Economic Taxonomy and Botany 4, 167–172.
Curator

Record - 18 of 82 [TOP]

Compound ID	1569
Compound Structure
Plant Source	Cucurbita maxima Duchesne Common Name:Red Gourd, Red Pumpkin (English), Peeta Kuushmaanda, Kuushmaandaka (Sanskrit)
Source Family	Cucurbitaceae
Origin	India
Plant Part Used	Fruit
Extract	Water
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done	Broth Dilution Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)	< 1:20 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Diuretic, cures kapha, tonic, migraine, inflammation, boils, neuralgia
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34
Curator

Record - 19 of 82 [TOP]

Compound ID	1577
Compound Structure
Plant Source	Curcuma domesticata Valeton syn. Curcuma longa L. Common Name:Turmeric (English), Haridraa, Priyaka, Haridruma, Kshanda, Gauri (Sanskrit)
Source Family	Zingiberaceae
Origin	India
Plant Part Used	Leaf
Extract	Water
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done	Broth Dilution Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)	< 1:40 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Bronchitis, leprosy, random screening
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34 2) Jain, S.K., Tarafder, C.R., 1970. Medicinal plant lore of the Santals. A revival of P.O. Boddings, work. Economic Botany 24, 241–278
Curator

Record - 20 of 82 [TOP]

Compound ID	1592
Compound Structure
Plant Source	Daucus carota L. Common Name:Carrot (English), Gaajara, Garjara, Granjana (Sanskrit)
Source Family	Apiaceae (Umbelliferae)
Origin	India
Plant Part Used	Leaf
Extract	Water
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done	Broth Dilution Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)	< 1:20 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Leprosy, asthma, expectorant, chest troubles, bronchitis
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34 2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 14. Lalit Mohan Basu, Allahabad, India
Curator

Record - 21 of 82 [TOP]

Compound ID	1633
Compound Structure
Plant Source	Equisetum arvense L. Common Name:Field Horsetail (English), Ashwa - Puchha (Sanskrit)
Source Family	Equisetaceae
Origin	India, Britain and Northern temperate region
Plant Part Used	Leaf
Extract	Water
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done	Broth Dilution Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml	< 1:40 dilution
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Recommended and effective in treatment of tuberculosis by older herbalists. Proved very effectual in spitting of blood.
PubMed ID [Source Literature]	11744296
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Newton SM, Lau C, Gurcha SS, Besra GS, Wright CW.The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis.J Ethnopharmacol. 2002 Jan;79(1):57-67 2) Fitzpatrick, F.K., 1954. Plant substances active against Mycobacterium tuberculosis. Antibiotics and Chemotherapy 4, 528–536.
Curator

Record - 22 of 82 [TOP]

Compound ID	1791
Compound Structure
Plant Source	Galium aparine L. Common Name:Goosegrass, Clivers, Cleavers, Catch Weed (English), Choleretic, Stomachic (Sanskrit)
Source Family	Rubiaceae
Origin	India
Plant Part Used	Leaf
Extract	Water
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done	Broth Dilution Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)	< 1:40 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Aperient, diuretic, refrigerant, antiscorbutic and fruits used as a substitute for coffee
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34 2) Chopra, R.N., Nayar, S.L., Chopra, R.C., 1956. Glossary of Indian Medicinal Plants. Council of Scientific and Industrial Research, New Delhi, India.
Curator

Record - 23 of 82 [TOP]

Compound ID	1864
Compound Structure
Plant Source	Hibiscus esculentus L. syn. Abelmoschus esculentus (L.) Moench. Common Name:Ladies Finger, Gumbo, Okra (English), Bhaandi, Bhindaka (Sanskrit)
Source Family	Malvaceae
Origin	India
Plant Part Used	Leaf
Extract	Water
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done	Broth Dilution Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)	< 1:20 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Bronchitis, cough
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34 2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 14. Lalit Mohan Basu, Allahabad, India
Curator

Record - 24 of 82 [TOP]

Compound ID	1921
Compound Structure
Plant Source	Inula racemosa Hook. f. syn. Inula helenium L. Common Name:Elecampane (English), Pushkaramula, Pushkara, Paushkara, Padmapatra, Kaashmira, Kushtha - bheda (Sanskrit)
Source Family	Asteraceae (Compositae)
Origin	India
Plant Part Used	Leaf
Extract	Water
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done	Broth Dilution Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)	1:80 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Tuberculosis, lung disorders, cough, expectorant, random screening, bronchitis
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34
Curator

Record - 25 of 82 [TOP]

Compound ID	1948
Compound Structure
Plant Source	Juniperus communis Linn. Common Name:Common Juniper (English), Hapushaa, Havushaa, Haauber, Matsyagandha (Sanskrit)
Source Family	Cupressaceae
Origin	Worldwide, Mexico, India, British Columbia, particularly in Europe
Plant Part Used	Leaf
Extract	Water
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done	Broth Dilution Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)	1:40 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Antiseptic properties. In France berries used in treatment of scrofula and chest complaints
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34 2) http://plants.usda.gov/java/profile?symbol=JUCO6
Curator

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