| Compound ID | 1003 |
| Compound Structure | |
| Plant Source | Abrus precatorius L. Common Name:Indian Wild Liquorice, Jequirity, Crab's Eye (English), Gunja, Gunjaka (Sanskrit) |
| Source Family | Fabaceae |
| Origin | India, Puerto Rico, Nigeria |
| Plant Part Used | |
| Extract | Hexane (21.33 %) |
| Target Bacteria | Mycobacterium bovis (BCG - Bacillus Calmette Guerin) |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Rifampin (0.03 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 1250 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | N/A |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculous glands, asthma, pain in chest, cough, bronchitis, folklore medicine of Puerto Rico |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mann, A., Ibrahim, K., Oyewale, A.O., Amupitan, J.O., and Okogun, J.I., 2009, Antimycobacterial activity of some medicinal plants in Niger State, Nigeria. Afri. J. Infect. Dis., 3(2), 44-48
2) Indian Medicinal Plants: An Illustrated Dictionary By C.P. Khare
|
| Curator | |
| Compound ID | 1012 |
| Compound Structure | |
| Plant Source | Acacia nilotica (L.) Willd. ex Del. subsp. kraussiana (Benth.) Brenan Common Name:Indian Gum Arabic Tree |
| Source Family | Fabaceae |
| Origin | Africa |
| Plant Part Used | Leaf |
| Extract | Ethyl acetate |
| Target Bacteria | Mycobacterium aurum A+ |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Ciprofloxacin (1.8 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 780 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | N/A |
| PubChem ID | NR |
| Ethnomedicinal Information | Dry coughs, respiratory ailments including tuberculosis |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) I.M.S. Eldeen, J. Van Staden.Antimycobacterial activity of some trees used in South African traditional medicine.South African Journal of Botany, Volume 73, Issue 2, April 2007, Pages 248–251
|
| Curator | |
| Compound ID | 1013 |
| Compound Structure | |
| Plant Source | Acacia nilotica (L.) Willd. ex Del. subsp. kraussiana (Benth.) Brenan Common Name:Indian Gum Arabic Tree |
| Source Family | Fabaceae |
| Origin | Africa |
| Plant Part Used | Leaf |
| Extract | Ethanol |
| Target Bacteria | Mycobacterium aurum A+ |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Ciprofloxacin (1.8 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 195 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | N/A |
| PubChem ID | NR |
| Ethnomedicinal Information | Dry coughs, respiratory ailments including tuberculosis |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) I.M.S. Eldeen, J. Van Staden.Antimycobacterial activity of some trees used in South African traditional medicine.South African Journal of Botany, Volume 73, Issue 2, April 2007, Pages 248–251
|
| Curator | |
| Compound ID | 1014 |
| Compound Structure | |
| Plant Source | Acacia nilotica (L.) Willd. ex Del. subsp. kraussiana (Benth.) Brenan Common Name:Indian Gum Arabic Tree |
| Source Family | Fabaceae |
| Origin | Africa |
| Plant Part Used | Bark |
| Extract | Ethyl acetate |
| Target Bacteria | Mycobacterium aurum A+ |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Ciprofloxacin (1.8 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 780 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | N/A |
| PubChem ID | NR |
| Ethnomedicinal Information | Dry coughs, respiratory ailments including tuberculosis |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) I.M.S. Eldeen, J. Van Staden.Antimycobacterial activity of some trees used in South African traditional medicine.South African Journal of Botany, Volume 73, Issue 2, April 2007, Pages 248–251
|
| Curator | |
| Compound ID | 1015 |
| Compound Structure | |
| Plant Source | Acacia nilotica (L.) Willd. ex Del. subsp. kraussiana (Benth.) Brenan Common Name:Indian Gum Arabic Tree |
| Source Family | Fabaceae |
| Origin | Africa |
| Plant Part Used | Bark |
| Extract | Ethanol |
| Target Bacteria | Mycobacterium aurum A+ |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Ciprofloxacin (1.8 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 1560 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | N/A |
| PubChem ID | NR |
| Ethnomedicinal Information | Dry coughs, respiratory ailments including tuberculosis |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) I.M.S. Eldeen, J. Van Staden.Antimycobacterial activity of some trees used in South African traditional medicine.South African Journal of Botany, Volume 73, Issue 2, April 2007, Pages 248–251
|
| Curator | |
| Compound ID | 1017 |
| Compound Structure | |
| Plant Source | Acacia sieberiana DC. var. woodii (Burtt Davy) Keay & Brenan Common Name:Paperbark Thorn |
| Source Family | Fabaceae |
| Origin | Africa |
| Plant Part Used | Leaf |
| Extract | Ethyl acetate |
| Target Bacteria | Mycobacterium aurum A+ |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Ciprofloxacin (1.8 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 3120 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | N/A |
| PubChem ID | NR |
| Ethnomedicinal Information | Fever, infectious diseases, inflammation and pain in the back |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) I.M.S. Eldeen, J. Van Staden.Antimycobacterial activity of some trees used in South African traditional medicine.South African Journal of Botany, Volume 73, Issue 2, April 2007, Pages 248–251
|
| Curator | |
| Compound ID | 1018 |
| Compound Structure | |
| Plant Source | Acacia sieberiana DC. var. woodii (Burtt Davy) Keay & Brenan Common Name:Paperbark Thorn |
| Source Family | Fabaceae |
| Origin | Africa |
| Plant Part Used | Bark |
| Extract | Ethanol |
| Target Bacteria | Mycobacterium aurum A+ |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Ciprofloxacin (1.8 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 3120 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | N/A |
| PubChem ID | NR |
| Ethnomedicinal Information | Fever, infectious diseases, inflammation and pain in the back |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) I.M.S. Eldeen, J. Van Staden.Antimycobacterial activity of some trees used in South African traditional medicine.South African Journal of Botany, Volume 73, Issue 2, April 2007, Pages 248–251
|
| Curator | |
| Compound ID | 1019 |
| Compound Structure | |
| Plant Source | Acacia sieberiana DC. var. woodii (Burtt Davy) Keay & Brenan Common Name:Paperbark Thorn |
| Source Family | Fabaceae |
| Origin | Africa |
| Plant Part Used | Root |
| Extract | Dichloromethane |
| Target Bacteria | Mycobacterium aurum A+ |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Ciprofloxacin (1.8 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 6250 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | N/A |
| PubChem ID | NR |
| Ethnomedicinal Information | Fever, infectious diseases, inflammation and pain in the back |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) I.M.S. Eldeen, J. Van Staden.Antimycobacterial activity of some trees used in South African traditional medicine.South African Journal of Botany, Volume 73, Issue 2, April 2007, Pages 248–251
|
| Curator | |
| Compound ID | 1020 |
| Compound Structure | |
| Plant Source | Acacia sieberiana DC. var. woodii (Burtt Davy) Keay & Brenan Common Name:Paperbark Thorn |
| Source Family | Fabaceae |
| Origin | Africa |
| Plant Part Used | Root |
| Extract | Ethyl acetate |
| Target Bacteria | Mycobacterium aurum A+ |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Ciprofloxacin (1.8 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 3120 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | N/A |
| PubChem ID | NR |
| Ethnomedicinal Information | Fever, infectious diseases, inflammation and pain in the back |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) I.M.S. Eldeen, J. Van Staden.Antimycobacterial activity of some trees used in South African traditional medicine.South African Journal of Botany, Volume 73, Issue 2, April 2007, Pages 248–251
|
| Curator | |
| Compound ID | 1021 |
| Compound Structure | |
| Plant Source | Acacia sieberiana DC. var. woodii (Burtt Davy) Keay & Brenan Common Name:Paperbark Thorn |
| Source Family | Fabaceae |
| Origin | Africa |
| Plant Part Used | Root |
| Extract | Ethanol |
| Target Bacteria | Mycobacterium aurum A+ |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Ciprofloxacin (1.8 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 780 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | N/A |
| PubChem ID | NR |
| Ethnomedicinal Information | Fever, infectious diseases, inflammation and pain in the back |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) I.M.S. Eldeen, J. Van Staden.Antimycobacterial activity of some trees used in South African traditional medicine.South African Journal of Botany, Volume 73, Issue 2, April 2007, Pages 248–251
|
| Curator | |
| Compound ID | 1082 |
| Compound Structure | |
| Plant Source | Agrophyron repens Linn. Beauv. Common Name:Couch Grass |
| Source Family | Gramineae |
| Origin | Worldwide |
| Plant Part Used | Rhizome |
| Extract | Methanol (6.83 %) |
| Target Bacteria | Mycobacterium aurum |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Streptomycin (IC50 value 1.14) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | > 500 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Antibiotic |
| PubMed ID [Source Literature] | 11744296 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Newton SM, Lau C, Gurcha SS, Besra GS, Wright CW.The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis.J Ethnopharmacol. 2002 Jan;79(1):57-67
|
| Curator | |
| Compound ID | 1083 |
| Compound Structure | |
| Plant Source | Agrophyron repens Linn. Beauv. Common Name:Couch Grass |
| Source Family | Gramineae |
| Origin | Worldwide |
| Plant Part Used | Rhizome |
| Extract | Methanol (6.83 %) |
| Target Bacteria | Mycobacterium smegmatis |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Streptomycin (IC50 value 0.17) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | > 500 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Antibiotic |
| PubMed ID [Source Literature] | 11744296 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Newton SM, Lau C, Gurcha SS, Besra GS, Wright CW.The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis.J Ethnopharmacol. 2002 Jan;79(1):57-67
|
| Curator | |
| Compound ID | 1087 |
| Compound Structure | |
| Plant Source | Albizia adianthifolia (Schumach.)W. F.Wight Common Name:Flat Crown, Rough - Bark Flat Crown, West African Albizia |
| Source Family | Fabaceae |
| Origin | Africa |
| Plant Part Used | Root |
| Extract | Ethanol |
| Target Bacteria | Mycobacterium aurum A+ |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Ciprofloxacin (1.8 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 6250 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Fever, headaches, stomach problems, internal parasites and dysentery |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) I.M.S. Eldeen, J. Van Staden.Antimycobacterial activity of some trees used in South African traditional medicine.South African Journal of Botany, Volume 73, Issue 2, April 2007, Pages 248–251
2) http://www.worldagroforestry.org/sea/Products/AFDbases/af/asp/SpeciesInfo.asp?SpID=1760
|
| Curator | |
| Compound ID | 1188 |
| Compound Structure | |
| Plant Source | Annona senegalensis Common Name:Wild Custard Apple, Wild Soursop |
| Source Family | Annonaceae |
| Origin | Nigeria |
| Plant Part Used | |
| Extract | Methanol (71.7 %) |
| Target Bacteria | Mycobacterium bovis (BCG - Bacillus Calmette Guerin) |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Rifampin (0.03 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 1250 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mann, A., Ibrahim, K., Oyewale, A.O., Amupitan, J.O., and Okogun, J.I., 2009, Antimycobacterial activity of some me-dicinal plants in Niger State, Nigeria. Afri. J. Infect. Dis., 3(2), 44-48
|
| Curator | |
| Compound ID | 1191 |
| Compound Structure | |
| Plant Source | Anogeissus leiocarpus (DC.) Guill. & Perr. Common Name:African Birch |
| Source Family | Combretaceae |
| Origin | Nigeria |
| Plant Part Used | Root bark, stem bark |
| Extract | Crude methanol |
| Target Bacteria | Mycobacterium tuberculosis clinical isolate |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Ethambutol (2 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 78 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Asthma, cough, tuberculosis, worm killer, gonorrhoea |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mann, A., Amupitan, J.O., Oyewale, A.O., Okogun, J.I., Ibrahim, K., Oladosu, P., Lawson, L., Olajide, I., and Nnamdi, A., 2008, Evaluation of in vitro antimycobacterial activity of Nigerian plants used for treatment of respiratory diseases. Afr. J. Biotech., 7(11), 1630-1636
2) http://www.ajol.info/index.php/ajb/article/viewFile/58747/47072
|
| Curator | |
| Compound ID | 1192 |
| Compound Structure | |
| Plant Source | Anogeissus leiocarpus (DC.) Guill. & Perr. Common Name:African Birch |
| Source Family | Combretaceae |
| Origin | Nigeria |
| Plant Part Used | Root bark, stem bark |
| Extract | Hexane |
| Target Bacteria | Mycobacterium bovis (BCG - Bacillus Calmette Guerin) |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Rifampin (0.03 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 312.5 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Asthma, cough, tuberculosis, worm killer, gonorrhoea |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mann, A., Amupitan, J.O., Oyewale, A.O., Okogun, J.I., Ibrahim, K., Oladosu, P., Lawson, L., Olajide, I., and Nnamdi, A., 2008, Evaluation of in vitro antimycobacterial activity of Nigerian plants used for treatment of respiratory diseases. Afr. J. Biotech., 7(11), 1630-1636
2) http://www.ajol.info/index.php/ajb/article/viewFile/58747/47072
|
| Curator | |
| Compound ID | 1193 |
| Compound Structure | |
| Plant Source | Anogeissus leiocarpus (DC.) Guill. & Perr. Common Name:African Birch |
| Source Family | Combretaceae |
| Origin | Nigeria |
| Plant Part Used | Root bark, stem bark |
| Extract | Ethyl acetate soluble |
| Target Bacteria | Mycobacterium bovis (BCG - Bacillus Calmette Guerin) |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Rifampin (0.03 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 625 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Asthma, cough, tuberculosis, worm killer, gonorrhoea |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mann, A., Amupitan, J.O., Oyewale, A.O., Okogun, J.I., Ibrahim, K., Oladosu, P., Lawson, L., Olajide, I., and Nnamdi, A., 2008, Evaluation of in vitro antimycobacterial activity of Nigerian plants used for treatment of respiratory diseases. Afr. J. Biotech., 7(11), 1630-1636
2) http://www.ajol.info/index.php/ajb/article/viewFile/58747/47072
|
| Curator | |
| Compound ID | 1194 |
| Compound Structure | |
| Plant Source | Anogeissus leiocarpus (DC.) Guill. & Perr. Common Name:African Birch |
| Source Family | Combretaceae |
| Origin | Nigeria |
| Plant Part Used | Root bark, stem bark |
| Extract | Methanol |
| Target Bacteria | Mycobacterium bovis (BCG - Bacillus Calmette Guerin) |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Rifampin (0.03 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | > 1250 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Asthma, cough, tuberculosis, worm killer, gonorrhoea |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mann, A., Amupitan, J.O., Oyewale, A.O., Okogun, J.I., Ibrahim, K., Oladosu, P., Lawson, L., Olajide, I., and Nnamdi, A., 2008, Evaluation of in vitro antimycobacterial activity of Nigerian plants used for treatment of respiratory diseases. Afr. J. Biotech., 7(11), 1630-1636
2) http://www.ajol.info/index.php/ajb/article/viewFile/58747/47072
|
| Curator | |
| Compound ID | 1278 |
| Compound Structure | |
| Plant Source | Borago officinalis Linn. Common Name:Borage |
| Source Family | Boraginaceae |
| Origin | Europe, North Africa, North America |
| Plant Part Used | Herb |
| Extract | Methanol (19.44 %) |
| Target Bacteria | Mycobacterium aurum |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Streptomycin (IC50 value 1.14) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | > 500 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Used in pulmonary diseases, consumption and to treat fever |
| PubMed ID [Source Literature] | 11744296 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Newton SM, Lau C, Gurcha SS, Besra GS, Wright CW.The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis.J Ethnopharmacol. 2002 Jan;79(1):57-67
|
| Curator | |
| Compound ID | 1279 |
| Compound Structure | |
| Plant Source | Borago officinalis Linn. Common Name:Borage |
| Source Family | Boraginaceae |
| Origin | Europe, North Africa, North America |
| Plant Part Used | Herb |
| Extract | Methanol (19.44 %) |
| Target Bacteria | Mycobacterium smegmatis |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Streptomycin (IC50 value 0.17) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | > 500 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Used in pulmonary diseases, consumption and to treat fever |
| PubMed ID [Source Literature] | 11744296 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Newton SM, Lau C, Gurcha SS, Besra GS, Wright CW.The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis.J Ethnopharmacol. 2002 Jan;79(1):57-67
|
| Curator | |
| Compound ID | 1365 |
| Compound Structure | |
| Plant Source | Capparis brassii DC Common Name: |
| Source Family | Capparaceae |
| Origin | Nigeria |
| Plant Part Used | Root bark |
| Extract | Crude methanol |
| Target Bacteria | Mycobacterium tuberculosis clinical isolate |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Ethambutol (2 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 1250 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) A Mann, J O Amupitan, A O Oyewale, J I Okogun, K Ibrahim.An ethnobotanical survey of indigenous flora for treating tuberculosis and other respiratory diseases in Niger State, Nigeria.JOPAT Vol. 12 2007: pp. 1-21
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| Curator | |
| Compound ID | 1450 |
| Compound Structure | |
| Plant Source | Cinnamomum zeylandicum Breyn. Common Name:Cinnamon, Ceylon Cinnamon (English), Tvak, Daaruchini (Sanskrit) |
| Source Family | Lauraceae |
| Origin | Sri Lanka, Sumatra, Eastern Islands, Brazil, Mauritius, India, Jamaica |
| Plant Part Used | Bark |
| Extract | Methanol (9.41 %) |
| Target Bacteria | Mycobacterium avium |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Streptomycin (IC50 value 1.14) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | > 500 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Antiseptic and used to treat gonorrhoea, asthma, diabetes, diseases of oral cavity, bronchitis, expectorant |
| PubMed ID [Source Literature] | 11744296 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Newton SM, Lau C, Gurcha SS, Besra GS, Wright CW.The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis.J Ethnopharmacol. 2002 Jan;79(1):57-67
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| Curator | |
| Compound ID | 1451 |
| Compound Structure | |
| Plant Source | Cinnamomum zeylandicum Breyn. Common Name:Cinnamon, Ceylon Cinnamon (English),Tvak, Daaruchini (Sanskrit) |
| Source Family | Lauraceae |
| Origin | Sri Lanka, Sumatra, Eastern Islands, Brazil, Mauritius, India, Jamaica, Malaysia |
| Plant Part Used | Bark |
| Extract | Methanol (9.41 %) |
| Target Bacteria | Mycobacterium smegmatis |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Streptomycin (IC50 value 0.17) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | > 500 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Antiseptic and used to treat gonorrhoea, asthma, diabetes, diseases of oral cavity, bronchitis, expectorant |
| PubMed ID [Source Literature] | 11744296 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Newton SM, Lau C, Gurcha SS, Besra GS, Wright CW.The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis.J Ethnopharmacol. 2002 Jan;79(1):57-67
|
| Curator | |
| Compound ID | 1515 |
| Compound Structure | |
| Plant Source | Combretum kraussii Hochst. Common Name:Forest bushwillow |
| Source Family | Combretaceae |
| Origin | Africa |
| Plant Part Used | Leaf |
| Extract | Ethyl acetate |
| Target Bacteria | Mycobacterium aurum A+ |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Ciprofloxacin (1.8 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 1560 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Various stomach complaints, fever, wounds and inflammation |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) I.M.S. Eldeen, J. Van Staden.Antimycobacterial activity of some trees used in South African traditional medicine.South African Journal of Botany, Volume 73, Issue 2, April 2007, Pages 248–251
2) http://www.plantzAfrica.com/plantcd/combretkraus.htm
|
| Curator | |
| Compound ID | 1516 |
| Compound Structure | |
| Plant Source | Combretum kraussii Hochst. Common Name:Forest Bushwillow |
| Source Family | Combretaceae |
| Origin | Africa |
| Plant Part Used | Leaf |
| Extract | Ethanol |
| Target Bacteria | Mycobacterium aurum A+ |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Ciprofloxacin (1.8 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 195 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Various stomach complaints, fever, wounds and inflammation |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) I.M.S. Eldeen, J. Van Staden.Antimycobacterial activity of some trees used in South African traditional medicine.South African Journal of Botany, Volume 73, Issue 2, April 2007, Pages 248–251
2) http://www.plantzAfrica.com/plantcd/combretkraus.htm
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| Curator | |
