|  Home  |Search   |  Browse  |Similarity   |Data Visualization  |Submission  |Contact Us  |  













                  Page - 1 of 1                  Record - 1 of 3   [TOP]
Compound ID2202
Compound Structure
Plant SourceMorinda citrifolia L.     Common Name:Indian Mulberry (English), Ashyuka, Akshi, Atchy (Sanskrit)
Source FamilyRubiaceae
OriginMalaysia, India
Plant Part UsedLeaf
ExtractEthanol, hexane
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneBroth dilution assay using BACTEC system
Positive Control Used (conc.)Rifampin (0.125 µg/ml)
Inhibition [%]89 and 95 %
Activity [MIC] µg/ml100 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem IDNR
Ethnomedicinal InformationAsthma, joint pains, immune problems, pain relief, cellular regeneration, tuberculosis, respiratory disorders
PubMed ID [Source Literature]12410555
Extract PreparationN/A
Chemical Classification [Active Compound]N/A
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Reference(s)1) Saludes JP, Garson MJ, Franzblau SG, Aguinaldo AM.Antitubercular constituents from the hexane fraction of Morinda citrifolia Linn. (Rubiaceae).Phytother Res. 2002 Nov;16(7):683-5

2) http://www.motherherbs.com/morinda-citrifolia.html

Curator

                  Record - 2 of 3   [TOP]
Compound ID2203
Compound Structure
DOWNLOAD:
Plant SourceMorinda citrifolia L.     Common Name:Indian Mulberry (English), Ashyuka, Akshi, Atchy (Sanskrit)
Source FamilyRubiaceae
OriginMalaysia, India
Plant Part UsedLeaf
ExtractHexane
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneBroth dilution assay using BACTEC system
Positive Control Used (conc.)Rifampin (0.125 µg/ml)
Inhibition [%]Crude: 89% and Hexane: 95 %
Activity [MIC] µg/ml32 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified(E)-Phytol
PubChem ID   5280435
Ethnomedicinal InformationAsthma, joint pains, immune problems, pain relief, cellular regeneration, tuberculosis, respiratory disorders
PubMed ID [Source Literature]12410555
Extract PreparationN/A
Chemical Classification [Active Compound]Aliphatic, Alkene, Terpene, Diterpene, Alcohol
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight296.308
Molecular FormulaC20H40O
SMILESOC/C=C(/CCC[C@@H](CCC[C@@H](CCCC(C)C)C)C)C
XLogP8.949
PSA20.230
H-bond Donor1
H-bond Acceptor1
No. of Rotatable Bond Count13
No. of Rings0
No. of N0
No. of O1
No. of S0
Reference(s)1) Saludes JP, Garson MJ, Franzblau SG, Aguinaldo AM.Antitubercular constituents from the hexane fraction of Morinda citrifolia Linn. (Rubiaceae).Phytother Res. 2002 Nov;16(7):683-5

2) http://www.motherherbs.com/morinda-citrifolia.html

Curator

                  Record - 3 of 3   [TOP]
Compound ID2204
Compound Structure
DOWNLOAD:
Plant SourceMorinda citrifolia L.     Common Name:Indian Mulberry (English), Ashyuka, Akshi, Atchy (Sanskrit)
Source FamilyRubiaceae
OriginIndo - Pacific region
Plant Part UsedLeaf
Extract
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneBroth dilution assay using BACTEC system
Positive Control Used (conc.)Rifampin (0.125 µg/ml)
Inhibition [%]Crude ethanol extract - 89 % and hexane fraction - 95 %
Activity [MIC] µg/ml> 64 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound IdentifiedCycloartenol
PubChem ID   17750995
Ethnomedicinal InformationAsthma, joint pains, immune problems, pain relief, cellular regeneration, tuberculosis, respiratory disorders
PubMed ID [Source Literature]12410555
Extract PreparationDried leaves were extracted with ethanol to give a green, syrupy extract which was further partitioned into hexane DCM , EtOAc and n - BuOH fractions
Chemical Classification [Active Compound]Alicyclic, Pentacyclic, Terpene, Triterpene, Cycloartane, Prenylated, Alcohol
Media / Broth Used [Antimicrobial Assay/Test]Bactec 12B broth
Cytotoxicity Assay [AID]N/A
Molecular Weight426.386
Molecular FormulaC30H50O
SMILESO[C@@H]1C([C@H]2[C@@]3([C@]4(C3)[C@H]([C@]3([C@](CC4)([C@H](CC3)[C@@H](CCC=C(C)C)C)C)C)CC2)CC1)(C)C
XLogP11.921
PSA20.230
H-bond Donor1
H-bond Acceptor1
No. of Rotatable Bond Count4
No. of Rings5
No. of N0
No. of O1
No. of S0
Reference(s)1) Saludes JP, Garson MJ, Franzblau SG, Aguinaldo AM.Antitubercular constituents from the hexane fraction of Morinda citrifolia Linn. (Rubiaceae).Phytother Res. 2002 Nov;16(7):683-5

2) http://www.motherherbs.com/morinda-citrifolia.html

Curator


Developed by: CSIR- OSDD Unit, Delhi, India and Hosted by: Bioinformatics Centre,   Institute of Microbial Technology, Sec-39A, Chandigarh, India.
The website has been tested on the latest version of Google Chrome (34.0.1847.137 m) and Mozilla Firefox (29.0.1)