BioPhytMol: A database of Phytomolecules against Mycobacteria

| Home |

Simple Search

Query Builder

Structure Search

Browse |

Similarity

One to One

One to Many

Data Visualization |

Submission |

Page - 1 of 4 Record - 1 of 81 [TOP]

Compound ID	1145
Compound Structure
Plant Source	Alnus rubra Bong Common Name:Red Alder
Source Family	Betulaceae
Origin	British Columbia
Plant Part Used	Bark, Catkin
Extract	Methanol
Target Bacteria	Mycobacterium tuberculosis, Mycobacterium avium
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Isoniazid
Inhibition [%]	100 %
Activity [MIC] µg/ml	50 µg extract/Disc
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Bark is an appetizer, astringent, cathartic, cytostatic, emetic, stomachic and tonic, useful in treatment of headaches, rheumatic pains, internal injuries and diarrhoea
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) A.R. McCutcheon, R.W. Stokes, L.M. Thorson, S.M. Ellis, R.E.W. Hancock and G.H.N. Towers.Anti-Mycobacterial Screening of British Columbian Medicinal Plants.Pharmaceutical Biology, 1997, Vol. 35, No. 2 , Pages 77-83 2) http://www.pfaf.org/user/Plant.aspx?LatinName=Alnus%20rubra
Curator

Record - 2 of 81 [TOP]

Compound ID	1220
Compound Structure
Plant Source	Artocarpus lakoocha Roxb.Artocarpus lacucha Buch.-Ham Common Name:Monkey Jack (English), Lakuch, Kshudra Panas, Granthiphala, Pitanaasha (Sanskrit)
Source Family	Moraceae
Origin	India
Plant Part Used	Stem
Extract	Ethanol (95 %)
Target Bacteria	Mycobacterium smegmatis
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml	1 mg/Disc
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Leprosy, used as folkmedicine for other diseases
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34
Curator

Record - 3 of 81 [TOP]

Compound ID	1233
Compound Structure
Plant Source	Balsamorhiza sagittata (Pursh) Nutt. Common Name:Arrowleaf Balsamroot
Source Family	Meliaceae
Origin	British Columbia
Plant Part Used	Root
Extract	Methanol
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Isoniazid
Inhibition [%]	100 %
Activity [MIC] µg/ml	50 µg extract/Disc
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Stomach pains, colds, whooping cough, tuberculosis, fevers and headache, to treat sore mouths and throats, toothaches, for body aches such as rheumatism, on wounds, blisters, bites, swellings and sores (root), for dysentery (seeds)
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) A.R. McCutcheon, R.W. Stokes, L.M. Thorson, S.M. Ellis, R.E.W. Hancock and G.H.N. Towers.Anti-Mycobacterial Screening of British Columbian Medicinal Plants.Pharmaceutical Biology, 1997, Vol. 35, No. 2 , Pages 77-83
Curator

Record - 4 of 81 [TOP]

Compound ID	1245
Compound Structure
Plant Source	Bauhinia vahlii Wt. & Arn. Common Name:
Source Family	Caesalpiniaceae
Origin	India
Plant Part Used	Root
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Chloramphenicol
Inhibition [%]
Activity [MIC] µg/ml	3000000 µg/ml of dried plant material
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Dysentery, stomach ache, tonic, aphrodisiac, cuts, wounds
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34
Curator

Record - 5 of 81 [TOP]

Compound ID

1301

Compound Structure

Plant Source

Buddleja saligna L. Common Name:Squarestem Butterflybush

Source Family

Buddlejaceae

Origin

Africa

Plant Part Used

Leaf, stem

Extract

Hexane

Target Bacteria

Mycobacterium tuberculosis H37Rv

Assay / Test Done

Disk Diffusion Assay

Positive Control Used (conc.)

Rifampin (2.5 µg/disk)

Inhibition [%]

Activity [MIC] µg/ml

5 µg/Disk

Activity (In terms of dilution)

Activity (Zone of inhibition in mm)

Active Compound Identified

Oleanolic acid

PubChem ID

10494

Ethnomedicinal Information

Tuberculosis symptoms

PubMed ID [Source Literature]

18384988

Extract Preparation

N/A

Chemical Classification [Active Compound]

Alicyclic, Pentacyclic, Terpene, Triterpene, Acid, Alcohol

Media / Broth Used [Antimicrobial Assay/Test]

N/A

Cytotoxicity Assay [AID]

N/A

Molecular Weight

456.360

Molecular Formula

C₃₀H₄₈O₃

SMILES

O[C@@H]1C([C@H]2[C@@]([C@@H]3[C@]([C@]4(C(=CC3)[C@H]3[C@@](CC4)(CCC(C3)(C)C)C(=O)O)C)(CC2)C)(CC1)C)(C)C

XLogP

9.052

PSA

57.530

H-bond Donor

H-bond Acceptor

No. of Rotatable Bond Count

No. of Rings

No. of N

No. of O

No. of S

Reference(s)

1) Bamuamba K, Gammon DW, Meyers P, Dijoux-Franca MG, Scott G.Anti-mycobacterial activity of five plant species used as traditional medicines in the Western Cape Province (South Africa).J Ethnopharmacol. 2008 May 8;117(2):385-90

Curator

Record - 6 of 81 [TOP]

Compound ID	1425
Compound Structure
Plant Source	Chaenactis douglasii Hook. Common Name:Douglas Dustymaiden
Source Family	Asteraceae (Compositae)
Origin	British Columbia
Plant Part Used
Extract	Methanol
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Isoniazid
Inhibition [%]	100 %
Activity [MIC] µg/ml	50 µg extract/Disc
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Dressing for burns, wounds and sores
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) A.R. McCutcheon, R.W. Stokes, L.M. Thorson, S.M. Ellis, R.E.W. Hancock and G.H.N. Towers.Anti-Mycobacterial Screening of British Columbian Medicinal Plants.Pharmaceutical Biology, 1997, Vol. 35, No. 2 , Pages 77-83 2) Hunn, Eugene S. (1990). Nchi-Wana, "The Big River": Mid-Columbia Indians and Their Land. University of Washington Press. p. 352. ISBN 0-295-97119-3.
Curator

Record - 7 of 81 [TOP]

Compound ID	1508
Compound Structure
Plant Source	Colebrookea oppositifolia Smith Common Name:Indian Squirrel Tail (English)
Source Family	Lamiaceae
Origin	India
Plant Part Used	Whole plant
Extract	Ethanol
Target Bacteria	Mycobacterium smegmatis (MTCC 6), Mycobacterium smegmatis (MTCC 995)
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Rifampin (5.0 µg/Disc)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	17.3 ± 1.5 mm and 17 ± 0.0 mm
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Wound, epilepsy
PubMed ID [Source Literature]	21114505
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gupta VK, Shukla C, Bisht GR, Saikia D, Kumar S, Thakur RL.Detection of anti-tuberculosis activity in some folklore plants by radiometric BACTEC assay.Lett Appl Microbiol. 2011 Jan;52(1):33-40 2) http://www.flowersofIndia.net/catalog/slides/Indian%20Squirrel%20Tail.html
Curator

Record - 8 of 81 [TOP]

Compound ID	1532
Compound Structure
Plant Source	Conyza aegyptiaca (L.) Ait. Common Name:
Source Family	Asteraceae (Compositae)
Origin	India
Plant Part Used	Leaf
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	2 mg/Disc
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Skin diseases
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34
Curator

Record - 9 of 81 [TOP]

Compound ID	1541
Compound Structure
Plant Source	Corydalis rutaefolia Sibth. syn. Corydalis longipes D.Don · Prodr. Common Name:
Source Family	Papaveraceae
Origin	India
Plant Part Used	Whole plant
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Chloramphenicol
Inhibition [%]
Activity [MIC] µg/ml	2000000 µg/ml of dried plant material
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Typhoid fever
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34
Curator

Record - 10 of 81 [TOP]

Compound ID	1603
Compound Structure
Plant Source	Didymocarpus subalternans Wall. syn. Didymocarpus primulifolia Don Prodr. Common Name:
Source Family	Gesneriaceae
Origin	India
Plant Part Used	Whole plant
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Chloramphenicol
Inhibition [%]
Activity [MIC] µg/ml	2000000 µg/ml of dried plant
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Flu
PubMed ID [Source Literature]	7564413
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Taylor RS, Manandhar NP, Towers GH.Screening of selected medicinal plants of Nepal for antimicrobial activities.J Ethnopharmacol. 1995 Jun;46(3):153-9
Curator

Record - 11 of 81 [TOP]

Compound ID	1618
Compound Structure
Plant Source	Drymaria cordata Willd. Common Name:Whitesnow (English)
Source Family	Caryophyllaceae
Origin	India
Plant Part Used	Whole plant
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Chloramphenicol
Inhibition [%]
Activity [MIC] µg/ml	2000000 µg/ml of dried plant
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Asthma, cough, cold
PubMed ID [Source Literature]	7564413
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Taylor RS, Manandhar NP, Towers GH.Screening of selected medicinal plants of Nepal for antimicrobial activities.J Ethnopharmacol. 1995 Jun;46(3):153-9
Curator

Record - 12 of 81 [TOP]

Compound ID	1625
Compound Structure
Plant Source	Elephantopus scaber L. Common Name:Mayura Shikhaa, Gojihvaa (Sanskrit)
Source Family	Asteraceae (Compositae)
Origin	India
Plant Part Used	Whole plant
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Chloramphenicol
Inhibition [%]
Activity [MIC] µg/ml	2000000 µg/ml of dried plant
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Bronchitis, cough, cold
PubMed ID [Source Literature]	7564413
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Taylor RS, Manandhar NP, Towers GH.Screening of selected medicinal plants of Nepal for antimicrobial activities.J Ethnopharmacol. 1995 Jun;46(3):153-9 2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 1–4. Lalit Mohan Basu, Allahabad, India
Curator

Record - 13 of 81 [TOP]

Compound ID	1626
Compound Structure
Plant Source	Elsholtzia blanda Benth. Common Name:
Source Family	Lamiaceae
Origin	India
Plant Part Used	Aerial
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Chloramphenicol
Inhibition [%]
Activity [MIC] µg/ml	2000000 µg/ml of dried plant material
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Cough and cold
PubMed ID [Source Literature]	7564413
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Taylor RS, Manandhar NP, Towers GH.Screening of selected medicinal plants of Nepal for antimicrobial activities.J Ethnopharmacol. 1995 Jun;46(3):153-9
Curator

Record - 14 of 81 [TOP]

Compound ID	1627
Compound Structure
Plant Source	Empetrum nigrum L. Common Name:Black Crowberry
Source Family	Empetraceae
Origin	British Columbia
Plant Part Used	Stem
Extract	Methanol
Target Bacteria	Mycobacterium tuberculosis, Mycobacterium avium
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Isoniazid
Inhibition [%]	100 %
Activity [MIC] µg/ml	50 µg extract/Disc
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Fever, used as a diuretic, kidney problems, diarrhoea, colds
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) A.R. McCutcheon, R.W. Stokes, L.M. Thorson, S.M. Ellis, R.E.W. Hancock and G.H.N. Towers.Anti-Mycobacterial Screening of British Columbian Medicinal Plants.Pharmaceutical Biology, 1997, Vol. 35, No. 2 , Pages 77-83
Curator

Record - 15 of 81 [TOP]

Compound ID	1712
Compound Structure
Plant Source	Eupatorium odoratum L. Common Name:Thoroughwort (English)
Source Family	Asteraceae (Compositae)
Origin	India
Plant Part Used	Aerial
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Chloramphenicol
Inhibition [%]
Activity [MIC] µg/ml	300000 µg/ml of dried plant material
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Leprosy, dysentery, gastric complaints, pain, to stop bleeding, cuts, wounds
PubMed ID [Source Literature]	8866730
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Taylor RS, Edel F, Manandhar NP, Towers GH.Antimicrobial activities of southern Nepalese medicinal plants.J Ethnopharmacol. 1996 Feb;50(2):97-102
Curator

Record - 16 of 81 [TOP]

Compound ID	1761
Compound Structure
Plant Source	Flacourtia ramontchii L Herit Common Name:Ramontchi, Governor's Plum, Batoko Plum, Indian Plum (English), Aghori (Sanskrit)
Source Family	Flacourtiaceae
Origin	India
Plant Part Used	Leaf
Extract	Ethanol
Target Bacteria	Mycobacterium smegmatis (MTCC 6)
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Rifampin (5.0 µg/Disc)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	12.3 mm
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Dysentery, intestinal worm
PubMed ID [Source Literature]	21114505
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gupta VK, Shukla C, Bisht GR, Saikia D, Kumar S, Thakur RL.Detection of anti-tuberculosis activity in some folklore plants by radiometric BACTEC assay.Lett Appl Microbiol. 2011 Jan;52(1):33-40 2) http://iu.ff.cuni.cz/pandanus/database/details.php?id=1736
Curator

Record - 17 of 81 [TOP]

Compound ID	1773
Compound Structure
Plant Source	Fragaria vesca L. var. brateata(Heller) Davis Common Name:Woodland Strawberry (English)
Source Family	Rosaceae
Origin	India, British Columbia
Plant Part Used	Leaf
Extract	Methanol
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Isoniazid (10 µg/quadrant)
Inhibition [%]
Activity [MIC] µg/ml	50 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Astringent, diuretic, arthritis, gout, liver tonic, boosts your skin internally, digestive upsets, diarrhea, mild laxative action, improving digestion
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) A.R. McCutcheon, R.W. Stokes, L.M. Thorson, S.M. Ellis, R.E.W. Hancock and G.H.N. Towers.Anti-Mycobacterial Screening of British Columbian Medicinal Plants.Pharmaceutical Biology, 1997, Vol. 35, No. 2 , Pages 77-83 2) http://www.cmdr.ubc.ca/bobh/rjpdocs/173_1997_IntlJournPharmacog_35_p77.pdf
Curator

Record - 18 of 81 [TOP]

Compound ID	1774
Compound Structure
Plant Source	Fragaria vesca L. var. brateata(Heller) Davis Common Name:Woodland Strawberry (English)
Source Family	Rosaceae
Origin	India, British Columbia
Plant Part Used	Leaf
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Gentamicin (10 µg/Disc)
Inhibition [%]
Activity [MIC] µg/ml	20000 µg/ml of dried plant material
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	10.1 - 15.0 mm, > 25 mm (control)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Astringent, diuretic, arthritis, gout, liver tonic, boosts your skin internally, digestive upsets, diarrhea, mild laxative action, improving digestion
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) A.R. McCutcheon, R.W. Stokes, L.M. Thorson, S.M. Ellis, R.E.W. Hancock and G.H.N. Towers.Anti-Mycobacterial Screening of British Columbian Medicinal Plants.Pharmaceutical Biology, 1997, Vol. 35, No. 2 , Pages 77-83
Curator

Record - 19 of 81 [TOP]

Compound ID	1807
Compound Structure
Plant Source	Geum macrophyllum Willd.var. macrophyllum Common Name:Large - Leaved Avens
Source Family	Rosaceae
Origin	British Columbia
Plant Part Used
Extract	Methanol
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Isoniazid
Inhibition [%]	100 %
Activity [MIC] µg/ml	50 µg extract/Disc
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Stomach pain, tuberculosis
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) A.R. McCutcheon, R.W. Stokes, L.M. Thorson, S.M. Ellis, R.E.W. Hancock and G.H.N. Towers.Anti-Mycobacterial Screening of British Columbian Medicinal Plants.Pharmaceutical Biology, 1997, Vol. 35, No. 2 , Pages 77-83
Curator

Record - 20 of 81 [TOP]

Compound ID	1808
Compound Structure
Plant Source	Glehnia littoris F. Schmidt ssp Leiocarpa (Mathias) Hult. Common Name:Beach Silvertop, American Silvertop
Source Family	Apiaceae (Umbelliferae)
Origin	British Columbia
Plant Part Used	Root
Extract	Methanol
Target Bacteria	Mycobacterium tuberculosis, Mycobacterium avium
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Isoniazid
Inhibition [%]	100 %
Activity [MIC] µg/ml	50 µg extract/Disc
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Cough
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) A.R. McCutcheon, R.W. Stokes, L.M. Thorson, S.M. Ellis, R.E.W. Hancock and G.H.N. Towers.Anti-Mycobacterial Screening of British Columbian Medicinal Plants.Pharmaceutical Biology, 1997, Vol. 35, No. 2 , Pages 77-83 2) http://netartsbaytoday.org/html/white_flowers.html
Curator

Record - 21 of 81 [TOP]

Compound ID	1863
Compound Structure
Plant Source	Heracleum maximum Bartr. Common Name:Common Cowparsnip
Source Family	Apiaceae (Umbelliferae)
Origin	British Columbia
Plant Part Used	Root
Extract	Methanol
Target Bacteria	Mycobacterium tuberculosis, Mycobacterium avium
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Isoniazid
Inhibition [%]	100 %
Activity [MIC] µg/ml	50 µg extract/Disc
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Colic, cramps, headaches, sore throats, colds, coughs and flu, poultices used for sores, bruises, swelling, rheumatic joints and boils or other skin eruptions
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) A.R. McCutcheon, R.W. Stokes, L.M. Thorson, S.M. Ellis, R.E.W. Hancock and G.H.N. Towers.Anti-Mycobacterial Screening of British Columbian Medicinal Plants.Pharmaceutical Biology, 1997, Vol. 35, No. 2 , Pages 77-83 2) http://www.ionxchange.com/products/HERACLEUM-MAXIMUM-\|-Cow-Parnsip.html
Curator

Record - 22 of 81 [TOP]

Compound ID	1886
Compound Structure
Plant Source	Hypericum cordifolium Choisy Common Name:
Source Family	Hypericaceae
Origin	India
Plant Part Used	Aerial
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Chloramphenicol (2 g/ml)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	The allied species H. perforatum L. for chronic catarrh of lungs and H. japonicum Thunb. for asthma, used in ethnomedicine for other diseases
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Taylor RS, Manandhar NP, Towers GH.Screening of selected medicinal plants of Nepal for antimicrobial activities.J Ethnopharmacol. 1995 Jun;46(3):153-9 2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 1–4. Lalit
Curator

Record - 23 of 81 [TOP]

Compound ID	1887
Compound Structure
Plant Source	Hypericum elodeoides Choisy Common Name:
Source Family	Hypericaceae
Origin	India
Plant Part Used	Whole plant
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Chloramphenicol (2 g/ml)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Fever
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Taylor RS, Manandhar NP, Towers GH.Screening of selected medicinal plants of Nepal for antimicrobial activities.J Ethnopharmacol. 1995 Jun;46(3):153-9 2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 1–4. Lalit
Curator

Record - 24 of 81 [TOP]

Compound ID	1890
Compound Structure
Plant Source	Hypericum perforatum L. Common Name:Common St. John's wort (English)
Source Family	Hypericaceae
Origin	India, British Columbia
Plant Part Used	Aerial
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Gentamicin (10 µg/Disc)
Inhibition [%]
Activity [MIC] µg/ml	2000000 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	15.1 mm, 20.0 mm, > 25mm (control)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Wound healing, antiseptic and disinfectant qualities,cough, expectorant, chronic catarrh of lungs
PubMed ID [Source Literature]	1453710
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) McCutcheon AR, Ellis SM, Hancock RE, Towers GH.Antibiotic screening of medicinal plants of the British Columbian native peoples.J Ethnopharmacol. 1992 Oct;37(3):213-23
Curator

Record - 25 of 81 [TOP]

Compound ID	1893
Compound Structure
Plant Source	Hypericum perforatum L. Common Name:Common St. John's Wort (English)
Source Family	Hypericaceae
Origin	India, British Columbia
Plant Part Used	Whole plant
Extract	Methanol
Target Bacteria	Mycobacterium avium
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Isoniazid (10 µl of 10 mg/ml)
Inhibition [%]
Activity [MIC] µg/ml	10 µg extract/Disc
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Wound healing, antiseptic and disinfectant qualities,cough, expectorant, chronic catarrh of lungs
PubMed ID [Source Literature]	1453710
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) McCutcheon AR, Ellis SM, Hancock RE, Towers GH.Antibiotic screening of medicinal plants of the British Columbian native peoples.J Ethnopharmacol. 1992 Oct;37(3):213-23
Curator

Developed by: CSIR- OSDD Unit, Delhi, India and Hosted by: Bioinformatics Centre, Institute of Microbial Technology, Sec-39A, Chandigarh, India.
The website has been tested on the latest version of Google Chrome (34.0.1847.137 m) and Mozilla Firefox (29.0.1)