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                  Page - 1 of 1                  Record - 1 of 6   [TOP]
Compound ID1806
Compound Structure
Plant SourceGarcinia polyantha Oliv.     Common Name:
Source FamilyClusiaceae
OriginAfrica
Plant Part UsedStem bark
ExtractDichloromethane:Methanol
Target BacteriaMycobacterium smegmatis, Mycobacterium tuberculosis
Assay / Test Done
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)1:01 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem IDNR
Ethnomedicinal InformationWounds, various uses
PubMed ID [Source Literature]
Extract PreparationN/A
Chemical Classification [Active Compound]N/A
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Reference(s)1) Kuete V., Meli A.L., Komguem J., Louh G.N., Tangmouo J.G., Lontsi D., Meyer J.J.M., Lall N.Antimycobacterial, Antibacterial and Antifungal Activities of the Methanolic Extract and Compounds from Garcinia Polyantha. Pharmacologyonline 3 : 87-95 (2007)

Curator

                  Record - 2 of 6   [TOP]
Compound ID3588
Compound Structure
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Plant SourceCaleolaria pinnifolia Cav.     Common Name:NR
Source FamilyScrophulariaceae
OriginNR
Plant Part UsedAerial
ExtractDichloromethane:Methanol
Target BacteriaMycobacterium tuberculosis H37Rv (ATCC 27 294)
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)Rifampin (0.06 µg/ml)
Inhibition [%]NR
Activity [MIC] µg/ml4 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound Identified19 - Malonyloxydehydroabietinol
PubChem IDNR
Ethnomedicinal InformationNR
PubMed ID [Source Literature]12898418
Extract PreparationNR
Chemical Classification [Active Compound]Alicyclic, Tricyclic, Terpene, Diterpene, Malonyl
Media / Broth Used [Antimicrobial Assay/Test]NR
Cytotoxicity Assay [AID]NR
Molecular Weight372.230
Molecular FormulaC23H32O4
SMILESC1CC[C@](C2[C@@]1(c1c(CC2)cc(cc1)C(C)C)C)(C)COC(=O)CC(=O)O
XLogP8.774
PSA63.600
H-bond Donor1
H-bond Acceptor4
No. of Rotatable Bond Count6
No. of Rings3
No. of N0
No. of O4
No. of S0
Reference(s)1) Woldemichael GM, Franzblau SG, Zhang F, Wang Y, Timmermann BN.Inhibitory effect of sterols from Ruprechtia triflora and diterpenes from Calceolaria pinnifolia on the growth of Mycobacterium tuberculosis.Planta Med. 2003 Jul;69(7):628-31

CuratorReshmi, vikramjitmandal

                  Record - 3 of 6   [TOP]
Compound ID3589
Compound Structure
DOWNLOAD:
Plant SourceCaleolaria pinnifolia Cav.     Common Name:NR
Source FamilyScrophulariaceae
OriginNR
Plant Part UsedAerial
ExtractDichloromethane:Methanol
Target BacteriaMycobacterium tuberculosis H37Rv (ATCC 27 294)
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)Rifampin (0.06 µg/ml)
Inhibition [%]NR
Activity [MIC] µg/ml4 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound Identified19 - Methylmalonyloxy - Ent - Isopimara - 8(9), 15 - Diene
PubChem ID   639656
Ethnomedicinal InformationNR
PubMed ID [Source Literature]12898418
Extract PreparationNR
Chemical Classification [Active Compound]Alicyclic, Tricyclic, Terpene, Diterpene, Malonyl
Media / Broth Used [Antimicrobial Assay/Test]NR
Cytotoxicity Assay [AID]NR
Molecular Weight388.261
Molecular FormulaC24H36O4
SMILESO(C[C@]1([C@@H]2[C@](C3=C(CC2)C[C@](CC3)(C)C=C)(CCC1)C)C)C(=O)CC(=O)OC
XLogP6.720
PSA52.600
H-bond Donor0
H-bond Acceptor4
No. of Rotatable Bond Count7
No. of Rings3
No. of N0
No. of O4
No. of S0
Reference(s)1) Woldemichael GM, Franzblau SG, Zhang F, Wang Y, Timmermann BN.Inhibitory effect of sterols from Ruprechtia triflora and diterpenes from Calceolaria pinnifolia on the growth of Mycobacterium tuberculosis.Planta Med. 2003 Jul;69(7):628-31

CuratorReshmi, vikramjitmandal

                  Record - 4 of 6   [TOP]
Compound ID3590
Compound Structure
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Plant SourceCaleolaria pinnifolia Cav.     Common Name:NR
Source FamilyScrophulariaceae
OriginNR
Plant Part UsedAerial
ExtractDichloromethane:Methanol
Target BacteriaMycobacterium tuberculosis H37Rv (ATCC 27 294)
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)Rifampin (0.06 µg/ml)
Inhibition [%]NR
Activity [MIC] µg/ml8 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound Identified3 - Epi - Ursolic Acid
PubChem ID   64945
Ethnomedicinal InformationNR
PubMed ID [Source Literature]12898418
Extract PreparationNR
Chemical Classification [Active Compound]Alicyclic, Pentacyclic, Terpene, Triterpene, Acid, Alcohol
Media / Broth Used [Antimicrobial Assay/Test]NR
Cytotoxicity Assay [AID]NR
Molecular Weight456.360
Molecular FormulaC30H48O3
SMILESO[C@@H]1C([C@H]2[C@@]([C@@H]3[C@]([C@]4(C(=CC3)[C@H]3[C@@](CC4)(CC[C@H]([C@@H]3C)C)C(=O)O)C)(CC2)C)(CC1)C)(C)C
XLogP8.954
PSA57.530
H-bond Donor2
H-bond Acceptor3
No. of Rotatable Bond Count1
No. of Rings5
No. of N0
No. of O3
No. of S0
Reference(s)1) Woldemichael GM, Franzblau SG, Zhang F, Wang Y, Timmermann BN.Inhibitory effect of sterols from Ruprechtia triflora and diterpenes from Calceolaria pinnifolia on the growth of Mycobacterium tuberculosis.Planta Med. 2003 Jul;69(7):628-31

CuratorReshmi, vikramjitmandal

                  Record - 5 of 6   [TOP]
Compound ID3591
Compound Structure
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Plant SourceRuprechtia trifolia Griseb     Common Name:
Source FamilyPolynaceae
Origin
Plant Part UsedAerial
ExtractDichloromethane:Methanol
Target BacteriaMycobacterium tuberculosis H37Rv (ATCC 27294)
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)Rifampin (0.06 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml4 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified5α, 8α - Epidioxyergosta - 6, 22 - Dien - 3β - Yl Stearate
PubChem IDNR
Ethnomedicinal Information
PubMed ID [Source Literature]12898418
Extract Preparation
Chemical Classification [Active Compound]Alicyclic, Tetracyclic, Steroid, Peroxy, Ester, Stearate
Media / Broth Used [Antimicrobial Assay/Test]
Cytotoxicity Assay [AID]
Molecular Weight694.590
Molecular FormulaC46H78O4
SMILESC12[C@@]3([C@@]4(C=C[C@@]1(C1[C@](CC2)([C@H](CC1)[C@@H](/C=C/[C@@H](C(C)C)C)C)C)OO4)C[C@H](CC3)OC(=O)CCCCCCCCCCCCCCCCC)C
XLogP17.911
PSA44.760
H-bond Donor0
H-bond Acceptor4
No. of Rotatable Bond Count22
No. of Rings3
No. of N0
No. of O4
No. of S0
Reference(s)1) Woldemichael GM, Franzblau SG, Zhang F, Wang Y, Timmermann BN.Inhibitory effect of sterols from Ruprechtia triflora and diterpenes from Calceolaria pinnifolia on the growth of Mycobacterium tuberculosis.Planta Med. 2003 Jul;69(7):628-31

CuratorRachana, vikramjitmandal

                  Record - 6 of 6   [TOP]
Compound ID3593
Compound Structure
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Plant SourceRuprechtia trifolia Griseb     Common Name:
Source FamilyPolynaceae
Origin
Plant Part UsedAerial
ExtractDichloromethane:Methanol
Target BacteriaMycobacterium tuberculosis H37Rv (ATCC 27294)
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)Rifampin (0.06 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml2 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound IdentifiedStigmast - 4 - En - 6β - Ol - 3 - One
PubChem IDNR
Ethnomedicinal Information
PubMed ID [Source Literature]12898418
Extract Preparation
Chemical Classification [Active Compound]Alicyclic, Tetracyclic, Steroid, Ketone, Alcohol
Media / Broth Used [Antimicrobial Assay/Test]
Cytotoxicity Assay [AID]
Molecular Weight428.365
Molecular FormulaC29H48O2
SMILESC1CC(=O)C=C2C(CC3C4CCC(C4(C)CCC3C12C)C(C)CCC(CC)C(C)C)O
XLogP9.980
PSA37.300
H-bond Donor1
H-bond Acceptor2
No. of Rotatable Bond Count6
No. of Rings4
No. of N0
No. of O2
No. of S0
Reference(s)1) Woldemichael GM, Franzblau SG, Zhang F, Wang Y, Timmermann BN.Inhibitory effect of sterols from Ruprechtia triflora and diterpenes from Calceolaria pinnifolia on the growth of Mycobacterium tuberculosis.Planta Med. 2003 Jul;69(7):628-31

CuratorRachana, vikramjitmandal


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