BioPhytMol: A database of Phytomolecules against Mycobacteria

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Page - 1 of 1 Record - 1 of 19 [TOP]

Compound ID	1157
Compound Structure
Plant Source	Althaea ludwigii L. Common Name:
Source Family	Malvaceae
Origin	India
Plant Part Used	Aerial
Extract	Ethanol (80 %)
Target Bacteria	Mycobacterium smegmatis
Assay / Test Done	Agar Dilution - Streak Assay
Positive Control Used (conc.)
Inhibition [%]	Partial
Activity [MIC] µg/ml	1000 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Aperient used in herbal medicine for other diseases
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34
Curator

Record - 2 of 19 [TOP]

Compound ID	1215
Compound Structure
Plant Source	Artemisia scoparia Waldst. & Kit Common Name:Red Stem Wormwood (English)
Source Family	Asteraceae (Compositae)
Origin	India
Plant Part Used	Whole plant
Extract	Ethanol (80 %)
Target Bacteria	Mycobacterium smegmatis
Assay / Test Done	Agar Dilution - Streak Assay
Positive Control Used (conc.)
Inhibition [%]	Partial
Activity [MIC] µg/ml	1563 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Earache, purgative, used in herbal medicine for diseases
PubMed ID [Source Literature]	541687
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Al-Shamma A, Mitscher LA.Comprehensive survey of indigenous Iraqi plants for potential economic value. 1. Screening results of 327 species for alkaloids and antimicrobial agents.J Nat Prod. 1979 Nov-Dec;42(6):633-42 2) Sudhanshu Kumar Jain.Dictionary of Indian Folk Medicine and Ethnobotany:A Reference Manual of Man-Plant Relationships, Ethnic Groups & Ethnobotanists in India.Deep Publications, 1991 - 311 pages
Curator

Record - 3 of 19 [TOP]

Compound ID	1444
Compound Structure
Plant Source	Chrozophora tinctoria Hook.f. Common Name:Giradol (English)
Source Family	Euphorbiaceae
Origin	India
Plant Part Used	Aerial
Extract	Ethanol (80 %)
Target Bacteria	Mycobacterium smegmatis
Assay / Test Done	Agar Dilution - Streak Assay
Positive Control Used (conc.)
Inhibition [%]	Partial
Activity [MIC] µg/ml	1000 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	The allied species C. prostrata Dalz. for asthma, cough, cold, purgative, used as herbal medicine for other diseases
PubMed ID [Source Literature]	541687
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Al-Shamma A, Mitscher LA.Comprehensive survey of indigenous Iraqi plants for potential economic value. 1. Screening results of 327 species for alkaloids and antimicrobial agents.J Nat Prod. 1979 Nov-Dec;42(6):633-42 2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 1–4. Lalit Mohan Basu, Allahabad, India
Curator

Record - 4 of 19 [TOP]

Compound ID	1985
Compound Structure
Plant Source	Lamium amplexicaule L Common Name:Goldenseal
Source Family	Lamiaceae
Origin	India
Plant Part Used	Whole plant
Extract	Ethanol (80 %)
Target Bacteria	Mycobacterium intracellulare
Assay / Test Done	Agar - Dilution Test
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml	0.02 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	3 mm, 7 mm
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Laxative, stimulant, diaphoretic, rheumatism, influenza
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Richardson M.D., Peterson J.R., Clark A.M. Bioactivity screenings of plants selected on the basis of folkloric use or presence of lignans in a family. Phytotherapy Research, Volume 6, Issue 5, pages 274–278, September/October 1992
Curator

Record - 5 of 19 [TOP]

Compound ID	2015
Compound Structure
Plant Source	Lemna minor L Common Name:
Source Family	Lemnaceae
Origin	India
Plant Part Used	Whole plant
Extract	Ethanol (80 %)
Target Bacteria	Mycobacterium smegmatis
Assay / Test Done
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml	1000000 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Cutaneous disorders, astringent, diuretic, antiscorbutic, as a wash for ophthalmia
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34
Curator

Record - 6 of 19 [TOP]

Compound ID	2407
Compound Structure
Plant Source	Plantago psyllium L. Common Name:Sand Plantain (English)
Source Family	Plantaginaceae
Origin	India
Plant Part Used	Whole plant
Extract	Ethanol (80 %)
Target Bacteria	Mycobacterium smegmatis
Assay / Test Done	Agar Dilution - Streak Assay
Positive Control Used (conc.)
Inhibition [%]	Partial
Activity [MIC] µg/ml	1000 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Expectorant
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Al-Shamma A, Mitscher LA.Comprehensive survey of indigenous Iraqi plants for potential economic value. 1. Screening results of 327 species for alkaloids and antimicrobial agents.J Nat Prod. 1979 Nov-Dec;42(6):633-42 2) Anonymous, 1986. The Useful Plants of India. Council of Scientific and Industrial Research, New Delhi, India
Curator

Record - 7 of 19 [TOP]

Compound ID	2434
Compound Structure
Plant Source	Potamogeton natans L. Common Name:
Source Family	Potamogetonaceae
Origin	India
Plant Part Used	Aerial
Extract	Ethanol (80 %)
Target Bacteria	Mycobacterium smegmatis
Assay / Test Done	Agar Dilution - Streak Assay
Positive Control Used (conc.)
Inhibition [%]	Partial
Activity [MIC] µg/ml	1000 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Cold, fever, blood diseases, used in herbal medicine for other diseases
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Al-Shamma A, Mitscher LA.Comprehensive survey of indigenous Iraqi plants for potential economic value. 1. Screening results of 327 species for alkaloids and antimicrobial agents.J Nat Prod. 1979 Nov-Dec;42(6):633-42 2) Sharma, S.K., 1998. Medicinal Plants Used in Ayurveda. National Academy of Ayurveda, Ministry of Health and Family Welfare, Govt. of India, New Delhi, India
Curator

Record - 8 of 19 [TOP]

Compound ID	2435
Compound Structure
Plant Source	Potamogeton pectinatus L. Common Name:
Source Family	Potamogetonaceae
Origin	India
Plant Part Used	Aerial, seed
Extract	Ethanol (80 %)
Target Bacteria	Mycobacterium smegmatis
Assay / Test Done	Agar Dilution - Streak Assay
Positive Control Used (conc.)
Inhibition [%]	Partial
Activity [MIC] µg/ml	1000 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Cold, fever, blood diseases, used in herbal medicine for other diseases
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Al-Shamma A, Mitscher LA.Comprehensive survey of indigenous Iraqi plants for potential economic value. 1. Screening results of 327 species for alkaloids and antimicrobial agents.J Nat Prod. 1979 Nov-Dec;42(6):633-42 2) Sharma, S.K., 1998. Medicinal Plants Used in Ayurveda. National Academy of Ayurveda, Ministry of Health and Family Welfare, Govt. of India, New Delhi, India
Curator

Record - 9 of 19 [TOP]

Compound ID	2515
Compound Structure
Plant Source	Rumex dentatus L. Common Name:Toothed Dock (English)
Source Family	Polygonaceae
Origin	India
Plant Part Used	Whole plant
Extract	Ethanol (80 %)
Target Bacteria	Mycobacterium smegmatis
Assay / Test Done	Agar Dilution - Streak Assay
Positive Control Used (conc.)
Inhibition [%]	Partial
Activity [MIC] µg/ml	1000 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Skin diseases, cooling drink, used in herbal medicine for other diseases
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Al-Shamma A, Mitscher LA.Comprehensive survey of indigenous Iraqi plants for potential economic value. 1. Screening results of 327 species for alkaloids and antimicrobial agents.J Nat Prod. 1979 Nov-Dec;42(6):633-42 2) Sudhanshu Kumar Jain.Dictionary of Indian Folk Medicine and Ethnobotany:A Reference Manual of Man-Plant Relationships, Ethnic Groups & Ethnobotanists in India.Deep Publications, 1991 - 311 pages
Curator

Record - 10 of 19 [TOP]

Compound ID	2695
Compound Structure
Plant Source	Taxus baccata L Common Name:European Yew (English), Thunera, Sthauneya, Sthauneyaka, Shukapushpa, Dhaatri - Patra, Vikarna (Sanskrit)
Source Family	Taxaceae
Origin	India
Plant Part Used	Leaf
Extract	Ethanol (80 %)
Target Bacteria	Mycobacterium tuberculosis H37Ra
Assay / Test Done	Microplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)	Rifampin (0.0047 – 0.0095 µg/ml), Isoniazid (0.05 – 0.1 µg/ml), Kanamycin sulphate (2.5 – 5.0 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml	200 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Expectorant
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) N. Erdemoglu, B. Sener and P. Palittapongarnpim.Antimycobacterial activity of Taxus baccata.Pharmaceutical Biology, 2003, Vol. 41, No. 8 , Pages 614-615
Curator

Record - 11 of 19 [TOP]

Compound ID	2806
Compound Structure	N/A
Plant Source	Withania somnifera Dunal Common Name:Winter Cherry (English), Ashwagandhaa, Hayagandhaa, Ashwakanda, Gandharvagandhaa (Sanskrit)
Source Family	Solanaceae
Origin	India
Plant Part Used	Aerial
Extract	Ethanol (80 %)
Target Bacteria	Mycobacterium smegmatis
Assay / Test Done	Agar Dilution - Streak Assay
Positive Control Used (conc.)
Inhibition [%]	100 %
Activity [MIC] µg/ml	1000 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified	N/A
PubChem ID	NR
Ethnomedicinal Information	Tuberculous glands, bronchitis, asthma, consumption, cough, chest complaints
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Al-Shamma A, Mitscher LA.Comprehensive survey of indigenous Iraqi plants for potential economic value. 1. Screening results of 327 species for alkaloids and antimicrobial agents.J Nat Prod. 1979 Nov-Dec;42(6):633-42 2) Singh, V., Pandey, R.P., 1980. Medicinal plant lore of the tribals of eastern Rajasthan. Journal of Economic Taxonomy and Botany 1, 137–147
Curator

Record - 12 of 19 [TOP]

Compound ID	3175
Compound Structure	NR
Plant Source	Ammania baccifera L. Common Name:NR
Source Family	Lythraceae
Origin	India
Plant Part Used	Whole plant
Extract	Ethanol (80 %)
Target Bacteria	Mycobacterium smegmatis
Assay / Test Done	Agar - Dilution Test
Positive Control Used (conc.)	NR
Inhibition [%]
Activity [MIC] µg/ml	1000 µg/ml
Activity (In terms of dilution)	NR
Activity (Zone of inhibition in mm)	NR
Active Compound Identified	NR
PubChem ID	NR
Ethnomedicinal Information	NR
PubMed ID [Source Literature]	541687
Extract Preparation	NR
Chemical Classification [Active Compound]	NR
Media / Broth Used [Antimicrobial Assay/Test]	NR
Cytotoxicity Assay [AID]	NR
Reference(s)	1) Al-Shamma A, Mitscher LA.Comprehensive survey of indigenous Iraqi plants for potential economic value. 1. Screening results of 327 species for alkaloids and antimicrobial agents.J Nat Prod. 1979 Nov-Dec;42(6):633-42
Curator	Najiya-beegum, vikramjitmandal

Record - 13 of 19 [TOP]

Compound ID	3191
Compound Structure	NR
Plant Source	Artemisia scoparia Waldst. & Kit Common Name:
Source Family	Asteraceae (Compositae)
Origin	India
Plant Part Used	Whole plant
Extract	Ethanol (80 %)
Target Bacteria	Mycobacterium smegmatis
Assay / Test Done	Agar Dilution - Streak Assay
Positive Control Used (conc.)	NR
Inhibition [%]	Partial
Activity [MIC] µg/ml	1000 µg/ml
Activity (In terms of dilution)	NR
Activity (Zone of inhibition in mm)	NR
Active Compound Identified	NR
PubChem ID	NR
Ethnomedicinal Information	Earache, purgative
PubMed ID [Source Literature]	541687
Extract Preparation	NR
Chemical Classification [Active Compound]	NR
Media / Broth Used [Antimicrobial Assay/Test]	NR
Cytotoxicity Assay [AID]	NR
Reference(s)	1) Al-Shamma A, Mitscher LA.Comprehensive survey of indigenous Iraqi plants for potential economic value. 1. Screening results of 327 species for alkaloids and antimicrobial agents.J Nat Prod. 1979 Nov-Dec;42(6):633-42
Curator	Reshmi, vikramjitmandal

Record - 14 of 19 [TOP]

Compound ID	3275
Compound Structure
Plant Source	Delphinium brunonianum Royle Common Name:
Source Family	Ranunculaceae
Origin	India
Plant Part Used	Aerial
Extract	Ethanol (80 %)
Target Bacteria	Mycobacterium smegmatis
Assay / Test Done	Agar Dilution - Streak Assay
Positive Control Used (conc.)
Inhibition [%]	Partial
Activity [MIC] µg/ml	1000 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Respiratory depressant
PubMed ID [Source Literature]	541687
Extract Preparation
Chemical Classification [Active Compound]
Media / Broth Used [Antimicrobial Assay/Test]
Cytotoxicity Assay [AID]
Reference(s)	1) Al-Shamma A, Mitscher LA.Comprehensive survey of indigenous Iraqi plants for potential economic value. 1. Screening results of 327 species for alkaloids and antimicrobial agents.J Nat Prod. 1979 Nov-Dec;42(6):633-42
Curator

Record - 15 of 19 [TOP]

Compound ID	3276
Compound Structure
Plant Source	Delphinium brunonianum Royle Common Name:
Source Family	Ranunculaceae
Origin	India
Plant Part Used	Root
Extract	Ethanol (80 %)
Target Bacteria	Mycobacterium smegmatis
Assay / Test Done	Agar Dilution - Streak Assay
Positive Control Used (conc.)
Inhibition [%]	Partial
Activity [MIC] µg/ml	1000 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Respiratory depressant
PubMed ID [Source Literature]	541687
Extract Preparation
Chemical Classification [Active Compound]
Media / Broth Used [Antimicrobial Assay/Test]
Cytotoxicity Assay [AID]
Reference(s)	1) Al-Shamma A, Mitscher LA.Comprehensive survey of indigenous Iraqi plants for potential economic value. 1. Screening results of 327 species for alkaloids and antimicrobial agents.J Nat Prod. 1979 Nov-Dec;42(6):633-42
Curator	Vsheeba, vikramjitmandal

Record - 16 of 19 [TOP]

Compound ID	3279
Compound Structure
Plant Source	Eclipta alba (L.) Hausskn Common Name:
Source Family	Asteraceae (Compositae)
Origin	India
Plant Part Used	Aerial
Extract	Ethanol (80 %)
Target Bacteria	Mycobacterium smegmatis
Assay / Test Done	Agar Dilution - Streak Assay
Positive Control Used (conc.)
Inhibition [%]	Partial
Activity [MIC] µg/ml	1000 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Leprosy, asthma, bronchitis, expectorant, bronchitis
PubMed ID [Source Literature]	541687
Extract Preparation	Ethanol (80 % extract)
Chemical Classification [Active Compound]
Media / Broth Used [Antimicrobial Assay/Test]
Cytotoxicity Assay [AID]
Reference(s)	1) Al-Shamma A, Mitscher LA.Comprehensive survey of indigenous Iraqi plants for potential economic value. 1. Screening results of 327 species for alkaloids and antimicrobial agents.J Nat Prod. 1979 Nov-Dec;42(6):633-42
Curator	Vsheeba

Record - 17 of 19 [TOP]

Compound ID	3318
Compound Structure
Plant Source	Luffa cylindrica (L.) Roem. Common Name:
Source Family	Cucurbitaceae
Origin	India
Plant Part Used	Aerial
Extract	Ethanol (80 %)
Target Bacteria	Mycobacterium smegmatis
Assay / Test Done	Agar Dilution - Streak Assay
Positive Control Used (conc.)	NR
Inhibition [%]	100 %
Activity [MIC] µg/ml	1000 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified	NR
PubChem ID	NR
Ethnomedicinal Information	Leprosy, bronchitis, expectorant
PubMed ID [Source Literature]	541687
Extract Preparation
Chemical Classification [Active Compound]	NR
Media / Broth Used [Antimicrobial Assay/Test]
Cytotoxicity Assay [AID]
Reference(s)	1) Al-Shamma A, Mitscher LA.Comprehensive survey of indigenous Iraqi plants for potential economic value. 1. Screening results of 327 species for alkaloids and antimicrobial agents.J Nat Prod. 1979 Nov-Dec;42(6):633-42
Curator	Rachana, vikramjitmandal

Record - 18 of 19 [TOP]

Compound ID	3319
Compound Structure	N/A
Plant Source	Peganum harmala L. Common Name:Wild Rue, Foreign Henna, Syrian Rue (English), Haramal, Isband (Sanskrit)
Source Family	Zygophyllaceae
Origin	India
Plant Part Used	Aerial
Extract	Ethanol (80 %)
Target Bacteria	Mycobacterium smegmatis
Assay / Test Done	Agar Dilution - Streak Assay
Positive Control Used (conc.)	NR
Inhibition [%]	100 %
Activity [MIC] µg/ml	1000 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified	N/A
PubChem ID	NR
Ethnomedicinal Information	Asthma, bronchitis, expectorant
PubMed ID [Source Literature]	541687
Extract Preparation
Chemical Classification [Active Compound]	NR
Media / Broth Used [Antimicrobial Assay/Test]
Cytotoxicity Assay [AID]
Reference(s)	1) Al-Shamma A, Mitscher LA.Comprehensive survey of indigenous Iraqi plants for potential economic value. 1. Screening results of 327 species for alkaloids and antimicrobial agents.J Nat Prod. 1979 Nov-Dec;42(6):633-42
Curator	Rachana, vikramjitmandal

Record - 19 of 19 [TOP]

Compound ID	3320
Compound Structure	N/A
Plant Source	Peganum harmala L. Common Name:Wild Rue, Foreign Henna, Syrian Rue (English), Haramal, Isband (Sanskrit)
Source Family	Zygophyllaceae
Origin	India
Plant Part Used	Seed
Extract	Ethanol (80 %)
Target Bacteria	Mycobacterium smegmatis
Assay / Test Done	Agar Dilution - Streak Assay
Positive Control Used (conc.)	NR
Inhibition [%]	100 %
Activity [MIC] µg/ml	1000 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified	N/A
PubChem ID	NR
Ethnomedicinal Information	Asthma, bronchitis, expectorant
PubMed ID [Source Literature]	541687
Extract Preparation
Chemical Classification [Active Compound]	NR
Media / Broth Used [Antimicrobial Assay/Test]
Cytotoxicity Assay [AID]
Reference(s)	1) Al-Shamma A, Mitscher LA.Comprehensive survey of indigenous Iraqi plants for potential economic value. 1. Screening results of 327 species for alkaloids and antimicrobial agents.J Nat Prod. 1979 Nov-Dec;42(6):633-42
Curator	Rachana, vikramjitmandal

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