| Compound ID | 2262 |
| Compound Structure | |
| Plant Source | Ocimum sanctum L. Common Name:Holy Basil, Sacred Basil (English), Tulasi, Surasaa, Surasa, Bhuutaghni, Suravalli, Sulabhaa (Sanskrit) |
| Source Family | Lamiaceae |
| Origin | India |
| Plant Part Used | Leaf |
| Extract | Ether |
| Target Bacteria | Mycobacterium tuberculosis B19 - 4 (human) |
| Assay / Test Done | Broth Dilution Assay |
| Positive Control Used (conc.) | Streptomycin (1 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 10 µg/ml |
| Activity (In terms of dilution) | 1:1 dilution |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Asthma, bronchitis, expectorant, cough, bronchitis, leprosy, cough, expectorant |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Gupta, K.C. and R. Viswanathan.A short note on antitubercular substance from Ocimum sanctum.1995, Antibiotics and Chemotherapy 5, 22-23
2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 1–4. Lalit Mohan Basu, Allahabad, India
|
| Curator | |
| Compound ID | 2263 |
| Compound Structure | |
| Plant Source | Ocimum sanctum L. Common Name:Holy Basil, Sacred Basil (English), Tulasi, Surasaa, Surasa, Bhuutaghni, Suravalli, Sulabhaa (Sanskrit) |
| Source Family | Lamiaceae |
| Origin | India |
| Plant Part Used | Leaf |
| Extract | Ether |
| Target Bacteria | Mycobacterium tuberculosis B19 - 1 (avian) |
| Assay / Test Done | Broth Dilution Assay |
| Positive Control Used (conc.) | Streptomycin (1 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 80 µg/ml |
| Activity (In terms of dilution) | 1:1 dilution |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Asthma, bronchitis, expectorant, cough, bronchitis, leprosy, cough, expectorant |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Gupta, K.C. and R. Viswanathan.A short note on antitubercular substance from Ocimum sanctum.1995, Antibiotics and Chemotherapy 5, 22-23
2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 1–4. Lalit Mohan Basu, Allahabad, India
|
| Curator | |
| Compound ID | 2287 |
| Compound Structure | |
| Plant Source | Panax ginseng Common Name:Asian Ginseng, Chinese Ginseng |
| Source Family | Araliaceae |
| Origin | China |
| Plant Part Used | Root |
| Extract | Ether |
| Target Bacteria | Mycobacterium tuberculosis H37Rv |
| Assay / Test Done | |
| Positive Control Used (conc.) | |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 100 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Treatment of diabetes, erectile dysfunction, fatigue, weakness, depression and anxiety |
| PubMed ID [Source Literature] | 113372 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Chang MW, Tasaka H, Kuwabara M, Watanabe T, Matsuo Y.Effects of panax ginseng extracts on the growth of Mycobacterium tuberculosis H37Rv.Hiroshima J Med Sci. 1979 Jun;28(2):115-8
|
| Curator | |
| Compound ID | 2791 |
| Compound Structure | |
| Plant Source | Viscum album L Common Name:European Mistletoe (English), Bandaaka, Suvarnabandaaka (Sanskrit) |
| Source Family | Viscaceae |
| Origin | India |
| Plant Part Used | Whole plant |
| Extract | Ether |
| Target Bacteria | Mycobacterium tuberculosis H37Ra |
| Assay / Test Done | Microplate Alamar Blue Assay (MABA) |
| Positive Control Used (conc.) | Rifampin (0.0047 – 0.0095 µg/ml), Isoniazid (0.05 – 0.1 µg/ml), Kanamycin sulphate (2.5 – 5.0 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 200 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Bodyache, spleen complaints, antifertility, used in ethnomedicine for other diseases |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) D. Deliorman, F. Ergun, B. Sener and P. Palittapongarnpim.Evaluation of Antimycobacterial Activity of Viscum album Subspecies.Pharmaceutical Biology, 2001, Vol.39, No.5, Pages 381-383
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| Curator | |
| Compound ID | 3177 |
| Compound Structure | NR |
| Plant Source | Ammorphophallus campanulatus Blume ex Decne Common Name:NR |
| Source Family | Araceae |
| Origin | India |
| Plant Part Used | Stem |
| Extract | Ether |
| Target Bacteria | Mycobacterium tuberculosis B19 - 3 (bovine) |
| Assay / Test Done | Tube Dilution Test |
| Positive Control Used (conc.) | NR |
| Inhibition [%] | NR |
| Activity [MIC] µg/ml | NR |
| Activity (In terms of dilution) | 3.51 dilution |
| Activity (Zone of inhibition in mm) | NR |
| Active Compound Identified | NR |
| PubChem ID | NR |
| Ethnomedicinal Information | Leprosy, asthma, bronchitis, respiratory disease, various fever, pulmonary disorders, cough, cold |
| PubMed ID [Source Literature] | |
| Extract Preparation | NR |
| Chemical Classification [Active Compound] | NR |
| Media / Broth Used [Antimicrobial Assay/Test] | NR |
| Cytotoxicity Assay [AID] | NR |
| Reference(s) | 1) Gupta, K.C., Viswananthan, R. (1956). Antitubercular substances from plants: A preliminary study. Antibiot. Chemother., 6, 194-195
|
| Curator | Najiya-beegum, vikramjitmandal |
| Compound ID | 1170 |
| Compound Structure | |
| Plant Source | Amorphophallus campanulatus Blume ex Decne Common Name:Arsaghna, Balukand (Sanskrit) |
| Source Family | Araceae |
| Origin | India |
| Plant Part Used | Stem |
| Extract | Ether |
| Target Bacteria | Mycobacterium tuberculosis B19 - 3 (bovine) |
| Assay / Test Done | |
| Positive Control Used (conc.) | |
| Inhibition [%] | |
| Activity [MIC] µg/ml | |
| Activity (In terms of dilution) | 1:5000 dilution |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Leprosy, asthma, bronchitis respiratory disease, various fever, pulmonary disorders |
| PubMed ID [Source Literature] | 17276637 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34
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| Curator | |