|  Home  |Search   |  Browse  |Similarity   |Data Visualization  |Submission  |Contact Us  |  













                  Page - 1 of 1                  Record - 1 of 4   [TOP]
Compound ID1931
Compound Structure
DOWNLOAD:
Plant SourceIpomoea leptophylla     Common Name:Bush Morning Glory, Manroot
Source FamilyConvolvulaceae
OriginNorth America
Plant Part UsedLeaf
ExtractSoluble extract
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneBACTEC 460 radiometric system
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/mlNR (inactive)
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound IdentifiedOperculinic acid
PubChem ID   44584575
Ethnomedicinal InformationTreatment for stomach troubles, tuberculosis
PubMed ID [Source Literature]14640518
Extract PreparationN/A
Chemical Classification [Active Compound]Aliphatic, Fatty acid, Sugar
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight1018.520
Molecular FormulaC46H82O24
SMILESO([C@@H]1O[C@H]([C@H](O[C@@H]2O[C@H]([C@H](O)[C@@H](O)[C@H]2O)C)[C@@H](O)[C@H]1O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)CO)C)[C@@H]1[C@@H](O)[C@@H](O)[C@@H](O[C@H]1C)O[C@@H]1[C@@H](O)[C@@H](O)[C@H](O[C@H]1O[C@H](CCCCCCCCCC(=O)O)CCCCC)C
XLogP1.041
PSA372.360
H-bond Donor13
H-bond Acceptor24
No. of Rotatable Bond Count25
No. of Rings5
No. of N0
No. of O24
No. of S0
Reference(s)1) Barnes CC, Smalley MK, Manfredi KP, Kindscher K, Loring H, Sheeley DM.Characterization of an anti-tuberculosis resin glycoside from the prairie medicinal plant Ipomoea leptophylla.J Nat Prod. 2003 Nov;66(11):1457-62

Curator

                  Record - 2 of 4   [TOP]
Compound ID1932
Compound Structure
DOWNLOAD:
Plant SourceIpomoea leptophylla     Common Name:Bush Morning Glory, Manroot
Source FamilyConvolvulaceae
OriginNorth America
Plant Part UsedLeaf
ExtractSoluble extract
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneBACTEC 460 radiometric system
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/mlNR
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound IdentifiedTrans - Cinnamic Acid
PubChem ID   444539
Ethnomedicinal InformationTreatment for stomach troubles, tuberculosis
PubMed ID [Source Literature]14640518
Extract PreparationN/A
Chemical Classification [Active Compound]Aromatic, Alkene, Acid
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight148.052
Molecular FormulaC9H8O2
SMILESOC(=O)/C=C/c1ccccc1
XLogP3.904
PSA37.300
H-bond Donor1
H-bond Acceptor2
No. of Rotatable Bond Count2
No. of Rings1
No. of N0
No. of O2
No. of S0
Reference(s)1) Barnes CC, Smalley MK, Manfredi KP, Kindscher K, Loring H, Sheeley DM.Characterization of an anti-tuberculosis resin glycoside from the prairie medicinal plant Ipomoea leptophylla.J Nat Prod. 2003 Nov;66(11):1457-62

Curator

                  Record - 3 of 4   [TOP]
Compound ID1933
Compound Structure
DOWNLOAD:
Plant SourceIpomoea leptophylla     Common Name:Bush Morning Glory, Manroot
Source FamilyConvolvulaceae
OriginNorth America
Plant Part UsedLeaf
ExtractSoluble extract
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneBACTEC 460 radiometric system
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/mlNR
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound IdentifiedPropanoic acid
PubChem ID   1032
Ethnomedicinal InformationTreatment for stomach troubles, tuberculosis
PubMed ID [Source Literature]14640518
Extract PreparationN/A
Chemical Classification [Active Compound]Aliphatic, Acid
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight74.037
Molecular FormulaC3H6O2
SMILESOC(=O)CC
XLogP0.173
PSA37.300
H-bond Donor1
H-bond Acceptor2
No. of Rotatable Bond Count1
No. of Rings0
No. of N0
No. of O2
No. of S0
Reference(s)1) Barnes CC, Smalley MK, Manfredi KP, Kindscher K, Loring H, Sheeley DM.Characterization of an anti-tuberculosis resin glycoside from the prairie medicinal plant Ipomoea leptophylla.J Nat Prod. 2003 Nov;66(11):1457-62

Curator

                  Record - 4 of 4   [TOP]
Compound ID1934
Compound Structure
DOWNLOAD:
Plant SourceIpomoea leptophylla     Common Name:Bush Morning Glory, Manroot
Source FamilyConvolvulaceae
OriginNorth America
Plant Part UsedLeaf
ExtractSoluble extract
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneBACTEC 460 radiometric system
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/mlNR
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound IdentifiedLauric acid
PubChem ID   3893
Ethnomedicinal InformationTreatment for stomach troubles, tuberculosis
PubMed ID [Source Literature]14640518
Extract PreparationN/A
Chemical Classification [Active Compound]Aliphatic, Fatty acid
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight200.178
Molecular FormulaC12H24O2
SMILESOC(=O)CCCCCCCCCCC
XLogP5.294
PSA37.300
H-bond Donor1
H-bond Acceptor2
No. of Rotatable Bond Count10
No. of Rings0
No. of N0
No. of O2
No. of S0
Reference(s)1) Barnes CC, Smalley MK, Manfredi KP, Kindscher K, Loring H, Sheeley DM.Characterization of an anti-tuberculosis resin glycoside from the prairie medicinal plant Ipomoea leptophylla.J Nat Prod. 2003 Nov;66(11):1457-62

Curator


Developed by: CSIR- OSDD Unit, Delhi, India and Hosted by: Bioinformatics Centre,   Institute of Microbial Technology, Sec-39A, Chandigarh, India.
The website has been tested on the latest version of Google Chrome (34.0.1847.137 m) and Mozilla Firefox (29.0.1)