BioPhytMol: A database of Phytomolecules against Mycobacteria

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Page - 1 of 7 Record - 1 of 155 [TOP]

Compound ID	1026
Compound Structure
Plant Source	Acalypha indica L. Common Name:Indian Acalypha (English), Arittamanjarie (Sanskrit)
Source Family	Euphorbiaceae
Origin	India
Plant Part Used	Leaf
Extract	Water
Target Bacteria	Mycobacterium tuberculosis H37Rv
Assay / Test Done	Middlebrook 7H9 Broth using BacT/ALERT 3D System
Positive Control Used (conc.)	Isoniazid, Rifampin
Inhibition [%]	68 %
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified	N/A
PubChem ID	NR
Ethnomedicinal Information	Respiratory disorder
PubMed ID [Source Literature]	20571171
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gupta R, Thakur B, Singh P, Singh HB, Sharma VD, Katoch VM, Chauhan SV.Anti-tuberculosis activity of selected medicinal plants against multi-drug resistant Mycobacterium tuberculosis isolates.Indian J Med Res. 2010 Jun;131:809-13 2) Indian Medicinal Plants: An Illustrated Dictionary By C.P. Khare
Curator

Record - 2 of 155 [TOP]

Compound ID	1027
Compound Structure
Plant Source	Acalypha indica L. Common Name:Indian Acalypha (English), Arittamanjarie (Sanskrit)
Source Family	Euphorbiaceae
Origin	India
Plant Part Used	Leaf
Extract	Water
Target Bacteria	Mycobacterium tuberculosis (Multi - Drug Resistant isolate DKU 156)
Assay / Test Done	Middlebrook 7H9 Broth using BacT/ALERT 3D System
Positive Control Used (conc.)	Isoniazid, Rifampin
Inhibition [%]	95 %
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified	N/A
PubChem ID	NR
Ethnomedicinal Information	Respiratory disorder
PubMed ID [Source Literature]	20571171
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gupta R, Thakur B, Singh P, Singh HB, Sharma VD, Katoch VM, Chauhan SV.Anti-tuberculosis activity of selected medicinal plants against multi-drug resistant Mycobacterium tuberculosis isolates.Indian J Med Res. 2010 Jun;131:809-13 2) Indian Medicinal Plants: An Illustrated Dictionary By C.P. Khare
Curator

Record - 3 of 155 [TOP]

Compound ID	1028
Compound Structure
Plant Source	Acalypha indica L. Common Name:Indian Acalypha (English), Arittamanjarie (Sanskrit)
Source Family	Euphorbiaceae
Origin	India
Plant Part Used	Leaf
Extract	Water
Target Bacteria	MDR stain of Mycobacterium tuberculosis (JAL1236)
Assay / Test Done	Middlebrook 7H9 Broth using BacT/ALERT 3D System
Positive Control Used (conc.)	Isoniazid, Rifampin
Inhibition [%]	68 %
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified	N/A
PubChem ID	NR
Ethnomedicinal Information	Respiratory disorder
PubMed ID [Source Literature]	20571171
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gupta R, Thakur B, Singh P, Singh HB, Sharma VD, Katoch VM, Chauhan SV.Anti-tuberculosis activity of selected medicinal plants against multi-drug resistant Mycobacterium tuberculosis isolates.Indian J Med Res. 2010 Jun;131:809-13 2) Indian Medicinal Plants: An Illustrated Dictionary By C.P. Khare
Curator

Record - 4 of 155 [TOP]

Compound ID	1029
Compound Structure
Plant Source	Acalypha indica L. Common Name:Indian Acalypha (English), Arittamanjarie (Sanskrit)
Source Family	Euphorbiaceae
Origin	India
Plant Part Used	Leaf
Extract	Water
Target Bacteria	Mycobacterium fortuitum (TMC 1529)
Assay / Test Done	Middlebrook 7H9 Broth using BacT/ALERT 3D System
Positive Control Used (conc.)	Isoniazid, Rifampin
Inhibition [%]	0 %
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified	N/A
PubChem ID	NR
Ethnomedicinal Information	Respiratory disorder
PubMed ID [Source Literature]	20571171
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gupta R, Thakur B, Singh P, Singh HB, Sharma VD, Katoch VM, Chauhan SV.Anti-tuberculosis activity of selected medicinal plants against multi-drug resistant Mycobacterium tuberculosis isolates.Indian J Med Res. 2010 Jun;131:809-13 2) Indian Medicinal Plants: An Illustrated Dictionary By C.P. Khare
Curator

Record - 5 of 155 [TOP]

Compound ID	1033
Compound Structure
Plant Source	Achillea millefolium L. Common Name:Yarrow (English), Brinjasipha (Sanskrit)
Source Family	Asteraceae (Compositae)
Origin	Mexico, India
Plant Part Used	Flower, leaf
Extract	Water
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done	Broth Dilution Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)	< 1:20 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified	N/A
PubChem ID	NR
Ethnomedicinal Information	Cough, tuberculosis, colds, flu, fever, astringent
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34
Curator

Record - 6 of 155 [TOP]

Compound ID	1052
Compound Structure	N/A
Plant Source	Adhatoda vasica Nees Common Name:Malabar Nut Tree (English), Vasaka (Sanskrit)
Source Family	Acanthaceae
Origin	India
Plant Part Used	Leaf
Extract	Water
Target Bacteria	Mycobacterium tuberculosis H37Rv
Assay / Test Done	Middlebrook 7H9 Broth using BacT/ALERT 3D System
Positive Control Used (conc.)	Isoniazid, Rifampin
Inhibition [%]	70 %
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified	N/A
PubChem ID	NR
Ethnomedicinal Information	Treatment of tuberculosis, asthma and also as expectorants, bronchial disorders such as acute and chronic cough, bronchitis
PubMed ID [Source Literature]	20571171
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gupta R, Thakur B, Singh P, Singh HB, Sharma VD, Katoch VM, Chauhan SV.Anti-tuberculosis activity of selected medicinal plants against multi-drug resistant Mycobacterium tuberculosis isolates.Indian J Med Res. 2010 Jun;131:809-13
Curator

Record - 7 of 155 [TOP]

Compound ID	1053
Compound Structure	N/A
Plant Source	Adhatoda vasica Nees Common Name:Malabar Nut Tree (English), Vasaka (Sanskrit)
Source Family	Acanthaceae
Origin	India
Plant Part Used	Leaf
Extract	Water
Target Bacteria	Mycobacterium tuberculosis (Multi - Drug Resistant isolate DKU 156)
Assay / Test Done	Middlebrook 7H9 Broth using BacT/ALERT 3D System
Positive Control Used (conc.)	Isoniazid, Rifampin
Inhibition [%]	32 %
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified	N/A
PubChem ID	NR
Ethnomedicinal Information	Treatment of tuberculosis, asthma and also as expectorants, bronchial disorders such as acute and chronic cough, bronchitis
PubMed ID [Source Literature]	20571171
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gupta R, Thakur B, Singh P, Singh HB, Sharma VD, Katoch VM, Chauhan SV.Anti-tuberculosis activity of selected medicinal plants against multi-drug resistant Mycobacterium tuberculosis isolates.Indian J Med Res. 2010 Jun;131:809-13
Curator

Record - 8 of 155 [TOP]

Compound ID	1054
Compound Structure	N/A
Plant Source	Adhatoda vasica Nees Common Name:Malabar Nut Tree (English),Vasaka (Sanskrit)
Source Family	Acanthaceae
Origin	India
Plant Part Used	Leaf
Extract	Water
Target Bacteria	MDR stain of Mycobacterium tuberculosis (JAL1236)
Assay / Test Done	Middlebrook 7H9 Broth using BacT/ALERT 3D System
Positive Control Used (conc.)	Isoniazid, Rifampin
Inhibition [%]	86 %
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified	N/A
PubChem ID	NR
Ethnomedicinal Information	Treatment of tuberculosis, asthma and also as expectorants, bronchial disorders such as acute and chronic cough, bronchitis
PubMed ID [Source Literature]	20571171
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gupta R, Thakur B, Singh P, Singh HB, Sharma VD, Katoch VM, Chauhan SV.Anti-tuberculosis activity of selected medicinal plants against multi-drug resistant Mycobacterium tuberculosis isolates.Indian J Med Res. 2010 Jun;131:809-13
Curator

Record - 9 of 155 [TOP]

Compound ID	1055
Compound Structure	N/A
Plant Source	Adhatoda vasica Nees Common Name:Malabar Nut Tree (English), Vasaka (Sanskrit)
Source Family	Acanthaceae
Origin	India
Plant Part Used	Leaf
Extract	Water
Target Bacteria	Mycobacterium fortuitum (TMC 1529)
Assay / Test Done	Middlebrook 7H9 Broth using BacT/ALERT 3D System
Positive Control Used (conc.)	Isoniazid, Rifampin
Inhibition [%]	0 %
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified	N/A
PubChem ID	NR
Ethnomedicinal Information	Treatment of tuberculosis, asthma and also as expectorants, bronchial disorders such as acute and chronic cough, bronchitis
PubMed ID [Source Literature]	20571171
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gupta R, Thakur B, Singh P, Singh HB, Sharma VD, Katoch VM, Chauhan SV.Anti-tuberculosis activity of selected medicinal plants against multi-drug resistant Mycobacterium tuberculosis isolates.Indian J Med Res. 2010 Jun;131:809-13
Curator

Record - 10 of 155 [TOP]

Compound ID	1094
Compound Structure
Plant Source	Allium cepa L. Common Name:Onion (English), Palaandu, Durgandh (Sanskrit)
Source Family	Amaryllidaceae
Origin	Malaysia, India
Plant Part Used	Bulb
Extract	Water
Target Bacteria	Mycobacterium tuberculosis H37Rv
Assay / Test Done	Middlebrook 7H9 Broth using BacT/ALERT 3D System
Positive Control Used (conc.)	Isoniazid, Rifampin
Inhibition [%]	35 %
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Cough
PubMed ID [Source Literature]	20571171
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gupta R, Thakur B, Singh P, Singh HB, Sharma VD, Katoch VM, Chauhan SV.Anti-tuberculosis activity of selected medicinal plants against multi-drug resistant Mycobacterium tuberculosis isolates.Indian J Med Res. 2010 Jun;131:809-13
Curator

Record - 11 of 155 [TOP]

Compound ID	1095
Compound Structure
Plant Source	Allium cepa L. Common Name:Onion (English), Palaandu, Durgandh (Sanskrit)
Source Family	Amaryllidaceae
Origin	Malaysia, India
Plant Part Used	Bulb
Extract	Water
Target Bacteria	Mycobacterium tuberculosis (Multi - Drug Resistant isolate DKU 156)
Assay / Test Done	Middlebrook 7H9 Broth using BacT/ALERT 3D System
Positive Control Used (conc.)	Isoniazid, Rifampin
Inhibition [%]	37 %
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Cough
PubMed ID [Source Literature]	20571171
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gupta R, Thakur B, Singh P, Singh HB, Sharma VD, Katoch VM, Chauhan SV.Anti-tuberculosis activity of selected medicinal plants against multi-drug resistant Mycobacterium tuberculosis isolates.Indian J Med Res. 2010 Jun;131:809-13
Curator

Record - 12 of 155 [TOP]

Compound ID	1096
Compound Structure
Plant Source	Allium cepa L. Common Name:Onion (English), Palaandu, Durgandh (Sanskrit)
Source Family	Amaryllidaceae
Origin	Malaysia, India
Plant Part Used	Bulb
Extract	Water
Target Bacteria	MDR stain of Mycobacterium tuberculosis (JAL1236)
Assay / Test Done	Middlebrook 7H9 Broth using BacT/ALERT 3D System
Positive Control Used (conc.)	Isoniazid, Rifampin
Inhibition [%]	79 %
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Cough
PubMed ID [Source Literature]	20571171
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gupta R, Thakur B, Singh P, Singh HB, Sharma VD, Katoch VM, Chauhan SV.Anti-tuberculosis activity of selected medicinal plants against multi-drug resistant Mycobacterium tuberculosis isolates.Indian J Med Res. 2010 Jun;131:809-13
Curator

Record - 13 of 155 [TOP]

Compound ID	1097
Compound Structure
Plant Source	Allium cepa L. Common Name:Onion (English), Palaandu, Durgandh (Sanskrit)
Source Family	Amaryllidaceae
Origin	Malaysia, India
Plant Part Used	Bulb
Extract	Water
Target Bacteria	Mycobacterium fortuitum (TMC 1529)
Assay / Test Done	Middlebrook 7H9 Broth using BacT/ALERT 3D System
Positive Control Used (conc.)	Isoniazid, Rifampin
Inhibition [%]	0 %
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Cough
PubMed ID [Source Literature]	20571171
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gupta R, Thakur B, Singh P, Singh HB, Sharma VD, Katoch VM, Chauhan SV.Anti-tuberculosis activity of selected medicinal plants against multi-drug resistant Mycobacterium tuberculosis isolates.Indian J Med Res. 2010 Jun;131:809-13
Curator

Record - 14 of 155 [TOP]

Compound ID	1099
Compound Structure
Plant Source	Allium sativum L. Common Name:Garlic (English), Lashuna (Sanskrit)
Source Family	Liliaceae
Origin	India, Africa, Malaysia
Plant Part Used	Leaf
Extract	Water
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done	Broth Dilution Assay
Positive Control Used (conc.)
Inhibition [%]	100 %
Activity [MIC] µg/ml
Activity (In terms of dilution)	1:640 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Bronchitis, asthma, expectorant, cough, pulmonary phthisis, consumption, chronic diseases of lungs, whooping cough, laryngeal tuberculosis
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34
Curator

Record - 15 of 155 [TOP]

Compound ID

1102

Compound Structure

Plant Source

Allium sativum L. Common Name:Garlic (English), Lashuna (Sanskrit)

Source Family

Amaryllidaceae

Origin

India, Africa, Malaysia

Plant Part Used

Bulb

Extract

Water

Target Bacteria

Mycobacterium tuberculosis

Assay / Test Done

Agar - Dilution Test

Positive Control Used (conc.)

Inhibition [%]

Activity [MIC] µg/ml

1670 µg/ml

Activity (In terms of dilution)

Activity (Zone of inhibition in mm)

Active Compound Identified

Allicin

PubChem ID

65036

Ethnomedicinal Information

Bronchitis, asthma, expectorant, cough, pulmonary phthisis, consumption, chronic diseases of lungs, whooping cough, laryngeal tuberculosis

PubMed ID [Source Literature]

4004189

Extract Preparation

N/A

Chemical Classification [Active Compound]

Aliphatic, Alkene, Disulfide

Media / Broth Used [Antimicrobial Assay/Test]

N/A

Cytotoxicity Assay [AID]

N/A

Molecular Weight

162.017

Molecular Formula

C₆H₁₀OS₂

SMILES

S(=O)(SCC=C)CC=C

XLogP

0.237

PSA

61.580

H-bond Donor

H-bond Acceptor

No. of Rotatable Bond Count

No. of Rings

No. of N

No. of O

No. of S

Reference(s)

1) Delaha EC, Garagusi VF.Inhibition of mycobacteria by garlic extract (Allium sativum).Antimicrob Agents Chemother. 1985 Apr;27(4):485-6

Curator

Record - 16 of 155 [TOP]

Compound ID

1103

Compound Structure

Plant Source

Allium sativum L. Common Name:Garlic (English), Lashuna (Sanskrit)

Source Family

Amaryllidaceae

Origin

India, Africa, Malaysia

Plant Part Used

Bulb

Extract

Water

Target Bacteria

Mycobacterium avium

Assay / Test Done

Agar - Dilution Test

Positive Control Used (conc.)

Inhibition [%]

Activity [MIC] µg/ml

3130 µg/ml

Activity (In terms of dilution)

Activity (Zone of inhibition in mm)

Active Compound Identified

Allicin

PubChem ID

65036

Ethnomedicinal Information

Bronchitis, asthma, expectorant, cough, pulmonary phthisis, consumption, chronic diseases of lungs, whooping cough, laryngeal tuberculosis

PubMed ID [Source Literature]

4004189

Extract Preparation

N/A

Chemical Classification [Active Compound]

Aliphatic, Alkene, Disulfide

Media / Broth Used [Antimicrobial Assay/Test]

N/A

Cytotoxicity Assay [AID]

N/A

Molecular Weight

162.017

Molecular Formula

C₆H₁₀OS₂

SMILES

S(=O)(SCC=C)CC=C

XLogP

0.237

PSA

61.580

H-bond Donor

H-bond Acceptor

No. of Rotatable Bond Count

No. of Rings

No. of N

No. of O

No. of S

Reference(s)

1) Delaha EC, Garagusi VF.Inhibition of mycobacteria by garlic extract (Allium sativum).Antimicrob Agents Chemother. 1985 Apr;27(4):485-6

Curator

Record - 17 of 155 [TOP]

Compound ID

1104

Compound Structure

Plant Source

Allium sativum L. Common Name:Garlic (English), Lashuna (Sanskrit)

Source Family

Amaryllidaceae

Origin

India, Africa, Malaysia

Plant Part Used

Bulb

Extract

Water

Target Bacteria

Mycobacterium bovis

Assay / Test Done

Agar - Dilution Test

Positive Control Used (conc.)

Inhibition [%]

Activity [MIC] µg/ml

1340 µg/ml

Activity (In terms of dilution)

Activity (Zone of inhibition in mm)

Active Compound Identified

Allicin

PubChem ID

65036

Ethnomedicinal Information

Bronchitis, asthma, expectorant, cough, pulmonary phthisis, consumption, chronic diseases of lungs, whooping cough, laryngeal tuberculosis

PubMed ID [Source Literature]

4004189

Extract Preparation

N/A

Chemical Classification [Active Compound]

Aliphatic, Alkene, Disulfide

Media / Broth Used [Antimicrobial Assay/Test]

N/A

Cytotoxicity Assay [AID]

N/A

Molecular Weight

162.017

Molecular Formula

C₆H₁₀OS₂

SMILES

S(=O)(SCC=C)CC=C

XLogP

0.237

PSA

61.580

H-bond Donor

H-bond Acceptor

No. of Rotatable Bond Count

No. of Rings

No. of N

No. of O

No. of S

Reference(s)

1) Delaha EC, Garagusi VF.Inhibition of mycobacteria by garlic extract (Allium sativum).Antimicrob Agents Chemother. 1985 Apr;27(4):485-6

Curator

Record - 18 of 155 [TOP]

Compound ID

1105

Compound Structure

Plant Source

Allium sativum L. Common Name:Garlic (English), Lashuna (Sanskrit)

Source Family

Amaryllidaceae

Origin

India, Africa, Malaysia

Plant Part Used

Bulb

Extract

Water

Target Bacteria

Mycobacterium chelonae

Assay / Test Done

Agar - Dilution Test

Positive Control Used (conc.)

Inhibition [%]

Activity [MIC] µg/ml

2000 µg/ml

Activity (In terms of dilution)

Activity (Zone of inhibition in mm)

Active Compound Identified

Allicin

PubChem ID

65036

Ethnomedicinal Information

Bronchitis, asthma, expectorant, cough, pulmonary phthisis, consumption, chronic diseases of lungs, whooping cough, laryngeal tuberculosis

PubMed ID [Source Literature]

4004189

Extract Preparation

N/A

Chemical Classification [Active Compound]

Aliphatic, Alkene, Disulfide

Media / Broth Used [Antimicrobial Assay/Test]

N/A

Cytotoxicity Assay [AID]

N/A

Molecular Weight

162.017

Molecular Formula

C₆H₁₀OS₂

SMILES

S(=O)(SCC=C)CC=C

XLogP

0.237

PSA

61.580

H-bond Donor

H-bond Acceptor

No. of Rotatable Bond Count

No. of Rings

No. of N

No. of O

No. of S

Reference(s)

1) Delaha EC, Garagusi VF.Inhibition of mycobacteria by garlic extract (Allium sativum).Antimicrob Agents Chemother. 1985 Apr;27(4):485-6

Curator

Record - 19 of 155 [TOP]

Compound ID

1106

Compound Structure

Plant Source

Allium sativum L. Common Name:Garlic (English), Lashuna (Sanskrit)

Source Family

Amaryllidaceae

Origin

India, Africa, Malaysia

Plant Part Used

Bulb

Extract

Water

Target Bacteria

Mycobacterium fortuitum

Assay / Test Done

Agar - Dilution Test

Positive Control Used (conc.)

Inhibition [%]

Activity [MIC] µg/ml

3350 µg/ml

Activity (In terms of dilution)

Activity (Zone of inhibition in mm)

Active Compound Identified

Allicin

PubChem ID

65036

Ethnomedicinal Information

Bronchitis, asthma, expectorant, cough, pulmonary phthisis, consumption, chronic diseases of lungs, whooping cough, laryngeal tuberculosis

PubMed ID [Source Literature]

4004189

Extract Preparation

N/A

Chemical Classification [Active Compound]

Aliphatic, Alkene, Disulfide

Media / Broth Used [Antimicrobial Assay/Test]

N/A

Cytotoxicity Assay [AID]

N/A

Molecular Weight

162.017

Molecular Formula

C₆H₁₀OS₂

SMILES

S(=O)(SCC=C)CC=C

XLogP

0.237

PSA

61.580

H-bond Donor

H-bond Acceptor

No. of Rotatable Bond Count

No. of Rings

No. of N

No. of O

No. of S

Reference(s)

1) Delaha EC, Garagusi VF.Inhibition of mycobacteria by garlic extract (Allium sativum).Antimicrob Agents Chemother. 1985 Apr;27(4):485-6

Curator

Record - 20 of 155 [TOP]

Compound ID

1107

Compound Structure

Plant Source

Allium sativum L. Common Name:Garlic (English), Lashuna (Sanskrit)

Source Family

Amaryllidaceae

Origin

India, Africa, Malaysia

Plant Part Used

Bulb

Extract

Water

Target Bacteria

Mycobacterium flavescens

Assay / Test Done

Agar - Dilution Test

Positive Control Used (conc.)

Inhibition [%]

Activity [MIC] µg/ml

3350 µg/ml

Activity (In terms of dilution)

Activity (Zone of inhibition in mm)

Active Compound Identified

Allicin

PubChem ID

65036

Ethnomedicinal Information

Bronchitis, asthma, expectorant, cough, pulmonary phthisis, consumption, chronic diseases of lungs, whooping cough, laryngeal tuberculosis

PubMed ID [Source Literature]

4004189

Extract Preparation

N/A

Chemical Classification [Active Compound]

Aliphatic, Alkene, Disulfide

Media / Broth Used [Antimicrobial Assay/Test]

N/A

Cytotoxicity Assay [AID]

N/A

Molecular Weight

162.017

Molecular Formula

C₆H₁₀OS₂

SMILES

S(=O)(SCC=C)CC=C

XLogP

0.237

PSA

61.580

H-bond Donor

H-bond Acceptor

No. of Rotatable Bond Count

No. of Rings

No. of N

No. of O

No. of S

Reference(s)

1) Delaha EC, Garagusi VF.Inhibition of mycobacteria by garlic extract (Allium sativum).Antimicrob Agents Chemother. 1985 Apr;27(4):485-6

Curator

Record - 21 of 155 [TOP]

Compound ID

1108

Compound Structure

Plant Source

Allium sativum L. Common Name:Garlic (English), Lashuna (Sanskrit)

Source Family

Amaryllidaceae

Origin

India, Africa, Malaysia

Plant Part Used

Bulb

Extract

Water

Target Bacteria

Mycobacterium gastri

Assay / Test Done

Agar - Dilution Test

Positive Control Used (conc.)

Inhibition [%]

Activity [MIC] µg/ml

2000 µg/ml

Activity (In terms of dilution)

Activity (Zone of inhibition in mm)

Active Compound Identified

Allicin

PubChem ID

65036

Ethnomedicinal Information

Bronchitis, asthma, expectorant, cough, pulmonary phthisis, consumption, chronic diseases of lungs, whooping cough, laryngeal tuberculosis

PubMed ID [Source Literature]

4004189

Extract Preparation

N/A

Chemical Classification [Active Compound]

Aliphatic, Alkene, Disulfide

Media / Broth Used [Antimicrobial Assay/Test]

N/A

Cytotoxicity Assay [AID]

N/A

Molecular Weight

162.017

Molecular Formula

C₆H₁₀OS₂

SMILES

S(=O)(SCC=C)CC=C

XLogP

0.237

PSA

61.580

H-bond Donor

H-bond Acceptor

No. of Rotatable Bond Count

No. of Rings

No. of N

No. of O

No. of S

Reference(s)

1) Delaha EC, Garagusi VF.Inhibition of mycobacteria by garlic extract (Allium sativum).Antimicrob Agents Chemother. 1985 Apr;27(4):485-6

Curator

Record - 22 of 155 [TOP]

Compound ID

1109

Compound Structure

Plant Source

Allium sativum L. Common Name:Garlic (English), Lashuna (Sanskrit)

Source Family

Amaryllidaceae

Origin

India, Africa, Malaysia

Plant Part Used

Bulb

Extract

Water

Target Bacteria

Mycobacterium intracellulare

Assay / Test Done

Agar - Dilution Test

Positive Control Used (conc.)

Inhibition [%]

Activity [MIC] µg/ml

3350 µg/ml

Activity (In terms of dilution)

Activity (Zone of inhibition in mm)

Active Compound Identified

Allicin

PubChem ID

65036

Ethnomedicinal Information

Bronchitis, asthma, expectorant, cough, pulmonary phthisis, consumption, chronic diseases of lungs, whooping cough, laryngeal tuberculosis

PubMed ID [Source Literature]

4004189

Extract Preparation

N/A

Chemical Classification [Active Compound]

Aliphatic, Alkene, Disulfide

Media / Broth Used [Antimicrobial Assay/Test]

N/A

Cytotoxicity Assay [AID]

N/A

Molecular Weight

162.017

Molecular Formula

C₆H₁₀OS₂

SMILES

S(=O)(SCC=C)CC=C

XLogP

0.237

PSA

61.580

H-bond Donor

H-bond Acceptor

No. of Rotatable Bond Count

No. of Rings

No. of N

No. of O

No. of S

Reference(s)

1) Delaha EC, Garagusi VF.Inhibition of mycobacteria by garlic extract (Allium sativum).Antimicrob Agents Chemother. 1985 Apr;27(4):485-6

Curator

Record - 23 of 155 [TOP]

Compound ID

1110

Compound Structure

Plant Source

Allium sativum L. Common Name:Garlic (English), Lashuna (Sanskrit)

Source Family

Amaryllidaceae

Origin

India, Africa, Malaysia

Plant Part Used

Bulb

Extract

Water

Target Bacteria

Mycobacterium kansasii

Assay / Test Done

Agar - Dilution Test

Positive Control Used (conc.)

Inhibition [%]

Activity [MIC] µg/ml

2450 µg/ml

Activity (In terms of dilution)

Activity (Zone of inhibition in mm)

Active Compound Identified

Allicin

PubChem ID

65036

Ethnomedicinal Information

Bronchitis, asthma, expectorant, cough, pulmonary phthisis, consumption, chronic diseases of lungs, whooping cough, laryngeal tuberculosis

PubMed ID [Source Literature]

4004189

Extract Preparation

N/A

Chemical Classification [Active Compound]

Aliphatic, Alkene, Disulfide

Media / Broth Used [Antimicrobial Assay/Test]

N/A

Cytotoxicity Assay [AID]

N/A

Molecular Weight

162.017

Molecular Formula

C₆H₁₀OS₂

SMILES

S(=O)(SCC=C)CC=C

XLogP

0.237

PSA

61.580

H-bond Donor

H-bond Acceptor

No. of Rotatable Bond Count

No. of Rings

No. of N

No. of O

No. of S

Reference(s)

1) Delaha EC, Garagusi VF.Inhibition of mycobacteria by garlic extract (Allium sativum).Antimicrob Agents Chemother. 1985 Apr;27(4):485-6

Curator

Record - 24 of 155 [TOP]

Compound ID

1111

Compound Structure

Plant Source

Allium sativum L. Common Name:Garlic (English), Lashuna (Sanskrit)

Source Family

Amaryllidaceae

Origin

India, Africa, Malaysia

Plant Part Used

Bulb

Extract

Water

Target Bacteria

Mycobacterium malmoense

Assay / Test Done

Agar - Dilution Test

Positive Control Used (conc.)

Inhibition [%]

Activity [MIC] µg/ml

2000 µg/ml

Activity (In terms of dilution)

Activity (Zone of inhibition in mm)

Active Compound Identified

Allicin

PubChem ID

65036

Ethnomedicinal Information

Bronchitis, asthma, expectorant, cough, pulmonary phthisis, consumption, chronic diseases of lungs, whooping cough, laryngeal tuberculosis

PubMed ID [Source Literature]

4004189

Extract Preparation

N/A

Chemical Classification [Active Compound]

Aliphatic, Alkene, Disulfide

Media / Broth Used [Antimicrobial Assay/Test]

N/A

Cytotoxicity Assay [AID]

N/A

Molecular Weight

162.017

Molecular Formula

C₆H₁₀OS₂

SMILES

S(=O)(SCC=C)CC=C

XLogP

0.237

PSA

61.580

H-bond Donor

H-bond Acceptor

No. of Rotatable Bond Count

No. of Rings

No. of N

No. of O

No. of S

Reference(s)

1) Delaha EC, Garagusi VF.Inhibition of mycobacteria by garlic extract (Allium sativum).Antimicrob Agents Chemother. 1985 Apr;27(4):485-6

Curator

Record - 25 of 155 [TOP]

Compound ID

1112

Compound Structure

Plant Source

Allium sativum L. Common Name:Garlic (English), Lashuna (Sanskrit)

Source Family

Amaryllidaceae

Origin

India, Africa, Malaysia

Plant Part Used

Bulb

Extract

Water

Target Bacteria

Mycobacterium marinum

Assay / Test Done

Agar - Dilution Test

Positive Control Used (conc.)

Inhibition [%]

Activity [MIC] µg/ml

2000 µg/ml

Activity (In terms of dilution)

Activity (Zone of inhibition in mm)

Active Compound Identified

Allicin

PubChem ID

65036

Ethnomedicinal Information

Bronchitis, asthma, expectorant, cough, pulmonary phthisis, consumption, chronic diseases of lungs, whooping cough, laryngeal tuberculosis

PubMed ID [Source Literature]

4004189

Extract Preparation

N/A

Chemical Classification [Active Compound]

Aliphatic, Alkene, Disulfide

Media / Broth Used [Antimicrobial Assay/Test]

N/A

Cytotoxicity Assay [AID]

N/A

Molecular Weight

162.017

Molecular Formula

C₆H₁₀OS₂

SMILES

S(=O)(SCC=C)CC=C

XLogP

0.237

PSA

61.580

H-bond Donor

H-bond Acceptor

No. of Rotatable Bond Count

No. of Rings

No. of N

No. of O

No. of S

Reference(s)

1) Delaha EC, Garagusi VF.Inhibition of mycobacteria by garlic extract (Allium sativum).Antimicrob Agents Chemother. 1985 Apr;27(4):485-6

Curator

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