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                  Page - 1 of 1                  Record - 1 of 5   [TOP]
Compound ID1456
Compound Structure
Plant SourceCissampelos pareira L.     Common Name:Velvet - Leaf Pareira, Pareira Brava (English)
Source FamilyMenispermaceae
OriginIndia, Puerto Rico
Plant Part UsedLeaf
ExtractEthanol (95 %)
Target BacteriaMycobacterium tuberculosis H37Rv
Assay / Test DoneMiddlebrook 7H9 Broth using BACTEC 460 System
Positive Control Used (conc.)Rifampin
Inhibition [%]60 %
Activity [MIC] µg/ml100 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem IDNR
Ethnomedicinal InformationFor menstrual problems, heart problems, asthma, stomach cramps, muscle pain/strains, irritable bowel syndrome, kidney stones, kidney/urinary infections and pain
PubMed ID [Source Literature]11746852
Extract PreparationThe plants were dried, at a temperature not exceeding 30°C, in an air - circulating oven. The material was powdered and extracted with 95% ethanol. The organic solvent was removed by distillation under reduced pressure
Chemical Classification [Active Compound]N/A
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Reference(s)1) Antoun MD, Ramos Z, Vazques J, Oquendo I, Proctor GR, Gerena L, Franzblau SG.Evaluation of the flora of Puerto Rico for in vitro antiplasmodial and antimycobacterial activities.Phytother Res. 2001 Nov;15(7):638-42

2) http://rainforest-database.com/plants/abuta.htm

Curator

                  Record - 2 of 5   [TOP]
Compound ID1588
Compound Structure
Plant SourceDalbergia monetaria L.f     Common Name:Moneybush
Source FamilyFabaceae
OriginPuerto Rico
Plant Part UsedStem
ExtractEthanol (95 %)
Target BacteriaMycobacterium tuberculosis H37Rv
Assay / Test DoneMiddlebrook 7H9 Broth using BACTEC 460 System
Positive Control Used (conc.)Rifampin
Inhibition [%]60 %
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem IDNR
Ethnomedicinal InformationTuberculosis
PubMed ID [Source Literature]11746852
Extract PreparationN/A
Chemical Classification [Active Compound]N/A
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Reference(s)1) Antoun MD, Ramos Z, Vazques J, Oquendo I, Proctor GR, Gerena L, Franzblau SG.Evaluation of the flora of Puerto Rico for in vitro antiplasmodial and antimycobacterial activities.Phytother Res. 2001 Nov;15(7):638-42

2) http://plants.usda.gov/java/profile?symbol=DAMO3

Curator

                  Record - 3 of 5   [TOP]
Compound ID1597
Compound Structure
Plant SourceDelonix regia (Bojer ex Hook.) Raf.     Common Name:Flamboyant Flame Tree, Gold Mohur (English), Gulmohar (Sanskrit)
Source FamilyCaesalpiniaceae
OriginIndia, Puerto Rico
Plant Part UsedStem
ExtractEthanol (95 %)
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneRadiorespirometric Bioassay
Positive Control Used (conc.)Rifampin (1 µg/ml)
Inhibition [%]60 %
Activity [MIC] µg/ml100 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem IDNR
Ethnomedicinal InformationSpider bite, folklore medicine of Puerto Rico
PubMed ID [Source Literature]11746852
Extract PreparationN/A
Chemical Classification [Active Compound]N/A
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Reference(s)1) Antoun MD, Ramos Z, Vazques J, Oquendo I, Proctor GR, Gerena L, Franzblau SG.Evaluation of the flora of Puerto Rico for in vitro antiplasmodial and antimycobacterial activities.Phytother Res. 2001 Nov;15(7):638-42

2) http://www.tropilab.com/delonix-reg.html

Curator

                  Record - 4 of 5   [TOP]
Compound ID2311
Compound Structure
Plant SourcePeperomia alata R.& P.     Common Name:
Source FamilyPiperaceae
OriginPeru
Plant Part UsedWhole plant
ExtractDichloromethane
Target BacteriaMycobacterium tuberculosis (ATCC 27294)
Assay / Test DoneBACTEC 460 (Becton Dickinson Diagnostic Instrument Systems, Sparks MD) Radiometric Assay
Positive Control Used (conc.)Rifampin (2 µg/ml ) and Ethambutol (7.5 µg/ml)
Inhibition [%]60 %
Activity [MIC] µg/ml50 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem IDNR
Ethnomedicinal InformationTuberculosis
PubMed ID [Source Literature]13678239
Extract PreparationN/A
Chemical Classification [Active Compound]N/A
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Reference(s)1) Graham JG, Pendland SL, Prause JL, Danzinger LH, Schunke Vigo J, Cabieses F, Farnsworth NR.Antimycobacterial evaluation of Peruvian plants.Phytomedicine. 2003;10(6-7):528-35

Curator

                  Record - 5 of 5   [TOP]
Compound ID3570
Compound Structure
Plant SourceHaplopappus sonorensis (A. Gray) S.F. Blake     Common Name:
Source FamilyAsteraceae (Compositae)
OriginMexico
Plant Part UsedWhole plant
ExtractLight petroleum, dichloromethane
Target BacteriaMycobacterium tuberculosis H37Rv (ATCC 27 294)
Assay / Test DoneBACTEC Assay
Positive Control Used (conc.)Rifampin
Inhibition [%]60 %
Activity [MIC] µg/ml100 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem IDNR
Ethnomedicinal InformationAntiviral, anti-inflammatory
PubMed ID [Source Literature]12727485
Extract PreparationSoxhlet extraction, concentrated in vacuo to dryness
Chemical Classification [Active Compound]
Media / Broth Used [Antimicrobial Assay/Test]
Cytotoxicity Assay [AID]Against HCT - 116 (ATCC CCL - 247)
Reference(s)1) Murillo JI, Encarnación-Dimayuga R, Malmstrĝm J, Christophersen C, Franzblau SG.Antimycobacterial flavones from Haplopappus sonorensis.Fitoterapia. 2003 Apr;74(3):226-30

CuratorGppreetha, vikramjitmandal


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