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                  Page - 1 of 1                  Record - 1 of 2   [TOP]
Compound ID1054
Compound StructureN/A
Plant SourceAdhatoda vasica Nees     Common Name:Malabar Nut Tree (English),Vasaka (Sanskrit)
Source FamilyAcanthaceae
OriginIndia
Plant Part UsedLeaf
ExtractWater
Target BacteriaMDR stain of Mycobacterium tuberculosis (JAL1236)
Assay / Test DoneMiddlebrook 7H9 Broth using BacT/ALERT 3D System
Positive Control Used (conc.)Isoniazid, Rifampin
Inhibition [%]86 %
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound IdentifiedN/A
PubChem IDNR
Ethnomedicinal InformationTreatment of tuberculosis, asthma and also as expectorants, bronchial disorders such as acute and chronic cough, bronchitis
PubMed ID [Source Literature]20571171
Extract PreparationN/A
Chemical Classification [Active Compound]N/A
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Reference(s)1) Gupta R, Thakur B, Singh P, Singh HB, Sharma VD, Katoch VM, Chauhan SV.Anti-tuberculosis activity of selected medicinal plants against multi-drug resistant Mycobacterium tuberculosis isolates.Indian J Med Res. 2010 Jun;131:809-13

Curator

                  Record - 2 of 2   [TOP]
Compound ID2328
Compound Structure
Plant SourcePhthrusa aff. stelis (L.) Kuijt     Common Name:
Source FamilyLoranthaceae
OriginPeru
Plant Part UsedLeaf
ExtractDichloromethane
Target BacteriaMycobacterium tuberculosis (ATCC 27294)
Assay / Test DoneBACTEC 460 (Becton Dickinson Diagnostic Instrument Systems, Sparks MD) Radiometric Assay
Positive Control Used (conc.)Rifampin (2 µg/ml), Ethambutol (7.5 µg/ml)
Inhibition [%]86 %
Activity [MIC] µg/ml50 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem IDNR
Ethnomedicinal InformationTuberculosis
PubMed ID [Source Literature]13678239
Extract PreparationN/A
Chemical Classification [Active Compound]N/A
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Reference(s)1) Graham JG, Pendland SL, Prause JL, Danzinger LH, Schunke Vigo J, Cabieses F, Farnsworth NR.Antimycobacterial evaluation of Peruvian plants.Phytomedicine. 2003;10(6-7):528-35

Curator


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