BioPhytMol: A database of Phytomolecules against Mycobacteria

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Page - 1 of 3 Record - 1 of 70 [TOP]

Compound ID	1091
Compound Structure
Plant Source	Alchornea glandulosa Common Name:
Source Family	Euphorbiaceae
Origin	Brazil
Plant Part Used	Leaf
Extract	Chloroform
Target Bacteria	Mycobacterium tuberculosis H37Rv (ATCC 27 294)
Assay / Test Done	Microplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)	Isoniazid (0.015 - 0.05 µg/ml)
Inhibition [%]	90 %
Activity [MIC] µg/ml	4000 µg/ml
Activity (In terms of dilution)	1:25 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Tuberculosis
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Pavan FR, Sato DN, Higuchi CT, Santos ACB, Vilegas W, Leite CQE 2009. In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants. Rev Bras Farmacogn 19: 204-206
Curator

Record - 2 of 70 [TOP]

Compound ID	1092
Compound Structure
Plant Source	Alchornea triplinervia Common Name:
Source Family	Euphorbiaceae
Origin	Brazil
Plant Part Used	Leaf
Extract	Chloroform, methanol
Target Bacteria	Mycobacterium tuberculosis H37Rv (ATCC 27 294)
Assay / Test Done	Microplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)	Isoniazid (0.015 - 0.05 µg/ml)
Inhibition [%]	90 %
Activity [MIC] µg/ml	4000 µg/ml
Activity (In terms of dilution)	1:25 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Tuberculosis
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Pavan FR, Sato DN, Higuchi CT, Santos ACB, Vilegas W, Leite CQE 2009. In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants. Rev Bras Farmacogn 19: 204-206
Curator

Record - 3 of 70 [TOP]

Compound ID	1172
Compound Structure
Plant Source	Anacardium Humile Common Name:Monkey Nut
Source Family	Anacardiaceae
Origin	Brazil
Plant Part Used	Leaf
Extract	Chloroform
Target Bacteria	Mycobacterium tuberculosis H37Rv (ATCC 27 294)
Assay / Test Done	Microplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)	Isoniazid (0.015 - 0.05 µg/ml)
Inhibition [%]	90 %
Activity [MIC] µg/ml	2000 µg/ml
Activity (In terms of dilution)	1:25 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Effective for the ailment medicated
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Pavan FR, Sato DN, Higuchi CT, Santos ACB, Vilegas W, Leite CQE 2009. In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants. Rev Bras Farmacogn 19: 204-206 2) http://www.ars-grin.gov/cgi-bin/duke/ethnobot.pl
Curator

Record - 4 of 70 [TOP]

Compound ID	1173
Compound Structure
Plant Source	Anacardium Humile Common Name:Monkey Nut
Source Family	Anacardiaceae
Origin	Brazil
Plant Part Used	Leaf
Extract	Methanol
Target Bacteria	Mycobacterium tuberculosis H37Rv (ATCC 27 294)
Assay / Test Done	Microplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)	Isoniazid (0.015 - 0.05 µg/ml)
Inhibition [%]	90 %
Activity [MIC] µg/ml	500 µg/ml
Activity (In terms of dilution)	1:25 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Effective for the ailment medicated
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Pavan FR, Sato DN, Higuchi CT, Santos ACB, Vilegas W, Leite CQE 2009. In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants. Rev Bras Farmacogn 19: 204-206
Curator

Record - 5 of 70 [TOP]

Compound ID	1177
Compound Structure
Plant Source	Ananas ananassoides Common Name:Cerrado Pineapple
Source Family	Bromeliaceae
Origin	Brazil
Plant Part Used	Leaf
Extract	Chloroform, methanol
Target Bacteria	Mycobacterium tuberculosis H37Rv (ATCC 27 294)
Assay / Test Done	Microplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)	Isoniazid (0.015 - 0.05 µg/ml)
Inhibition [%]	90 %
Activity [MIC] µg/ml	2000 µg/ml
Activity (In terms of dilution)	1:25 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Tuberculosis
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Pavan FR, Sato DN, Higuchi CT, Santos ACB, Vilegas W, Leite CQE 2009. In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants. Rev Bras Farmacogn 19: 204-206
Curator

Record - 6 of 70 [TOP]

Compound ID	1217
Compound Structure
Plant Source	Articun lappa Common Name:Burdock
Source Family	Asteraceae (Compositae)
Origin	Brazil
Plant Part Used	Leaf
Extract	Methanol
Target Bacteria	Mycobacterium tuberculosis H37Rv (ATCC 27 294)
Assay / Test Done	Microplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)	Isoniazid (0.015 - 0.05 µg/ml)
Inhibition [%]	90 %
Activity [MIC] µg/ml	4000 µg/ml
Activity (In terms of dilution)	1:25 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Tuberculosis
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Pavan FR, Sato DN, Higuchi CT, Santos ACB, Vilegas W, Leite CQE 2009. In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants. Rev Bras Farmacogn 19: 204-206
Curator

Record - 7 of 70 [TOP]

Compound ID	1293
Compound Structure
Plant Source	Bromelia balansal Common Name:
Source Family	Bromeliaceae
Origin	Brazil
Plant Part Used	Fruit
Extract	Chloroform, methanol
Target Bacteria	Mycobacterium tuberculosis H37Rv (ATCC 27 294)
Assay / Test Done	Microplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)	Isoniazid (0.015 - 0.05 µg/ml)
Inhibition [%]	90 %
Activity [MIC] µg/ml	2000 µg/ml
Activity (In terms of dilution)	1:25 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Tuberculosis
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Pavan FR, Sato DN, Higuchi CT, Santos ACB, Vilegas W, Leite CQE 2009. In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants. Rev Bras Farmacogn 19: 204-206
Curator

Record - 8 of 70 [TOP]

Compound ID	1311
Compound Structure
Plant Source	Byrsonima basiloba Common Name:
Source Family	Malpighiaceae
Origin	Brazil
Plant Part Used	Leaf
Extract	Chloroform
Target Bacteria	Mycobacterium tuberculosis H37Rv (ATCC 27 294)
Assay / Test Done	Microplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)	Isoniazid (0.015 - 0.05 µg/ml)
Inhibition [%]	90 %
Activity [MIC] µg/ml	125 µg/ml
Activity (In terms of dilution)	1:25 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Tuberculosis
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Pavan FR, Sato DN, Higuchi CT, Santos ACB, Vilegas W, Leite CQE 2009. In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants. Rev Bras Farmacogn 19: 204-206
Curator

Record - 9 of 70 [TOP]

Compound ID	1312
Compound Structure
Plant Source	Byrsonima basiloba Common Name:
Source Family	Malpighiaceae
Origin	Brazil
Plant Part Used	Leaf
Extract	Methanol
Target Bacteria	Mycobacterium tuberculosis H37Rv (ATCC 27 294)
Assay / Test Done	Microplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)	Isoniazid (0.015 - 0.05 µg/ml)
Inhibition [%]	90 %
Activity [MIC] µg/ml	250 µg/ml
Activity (In terms of dilution)	1:25 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Tuberculosis
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Pavan FR, Sato DN, Higuchi CT, Santos ACB, Vilegas W, Leite CQE 2009. In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants. Rev Bras Farmacogn 19: 204-206
Curator

Record - 10 of 70 [TOP]

Compound ID	1313
Compound Structure
Plant Source	Byrsonima coccolobifolia Common Name:
Source Family	Malpighiaceae
Origin	Brazil
Plant Part Used	Leaf
Extract	Methanol
Target Bacteria	Mycobacterium tuberculosis H37Rv (ATCC 27 294)
Assay / Test Done	Microplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)	Isoniazid (0.015 - 0.05 µg/ml)
Inhibition [%]	90 %
Activity [MIC] µg/ml	1000 µg/ml
Activity (In terms of dilution)	1:25 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Tuberculosis
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Pavan FR, Sato DN, Higuchi CT, Santos ACB, Vilegas W, Leite CQE 2009. In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants. Rev Bras Farmacogn 19: 204-206
Curator

Record - 11 of 70 [TOP]

Compound ID	1314
Compound Structure
Plant Source	Byrsonima crassa Common Name:
Source Family	Malpighiaceae
Origin	Brazil
Plant Part Used	Leaf
Extract	Chloroform
Target Bacteria	Mycobacterium tuberculosis H37Rv (ATCC 27 294)
Assay / Test Done	Microplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)	Isoniazid (0.015 - 0.05 µg/ml)
Inhibition [%]	90 %
Activity [MIC] µg/ml	125 µg/ml
Activity (In terms of dilution)	1:25 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Treatment of gastric disorders, diarrhea and infections
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Pavan FR, Sato DN, Higuchi CT, Santos ACB, Vilegas W, Leite CQE 2009. In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants. Rev Bras Farmacogn 19: 204-206
Curator

Record - 12 of 70 [TOP]

Compound ID	1315
Compound Structure
Plant Source	Byrsonima crassa Common Name:
Source Family	Malpighiaceae
Origin	Brazil
Plant Part Used	Leaf
Extract	Methanol
Target Bacteria	Mycobacterium tuberculosis H37Rv (ATCC 27 294)
Assay / Test Done	Microplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)	Isoniazid (0.015 - 0.05 µg/ml)
Inhibition [%]	90 %
Activity [MIC] µg/ml	1000 µg/ml
Activity (In terms of dilution)	1:25 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Treatment of gastric disorders, diarrhea and infections
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Pavan FR, Sato DN, Higuchi CT, Santos ACB, Vilegas W, Leite CQE 2009. In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants. Rev Bras Farmacogn 19: 204-206
Curator

Record - 13 of 70 [TOP]

Compound ID	1321
Compound Structure
Plant Source	Byrsonima crassa Common Name:
Source Family	Malpighiaceae
Origin	Brazil
Plant Part Used	Bark
Extract
Target Bacteria	Mycobacterium tuberculosis H37Rv (ATCC 27 294)
Assay / Test Done	Microplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)	Isoniazid (0.015 - 0.05 µg/ml)
Inhibition [%]	90 %
Activity [MIC] µg/ml	2000 µg/ml
Activity (In terms of dilution)	1:25 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Treatment of gastric disorders, diarrhea and infections
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Pavan FR, Sato DN, Higuchi CT, Santos ACB, Vilegas W, Leite CQE 2009. In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants. Rev Bras Farmacogn 19: 204-206
Curator

Record - 14 of 70 [TOP]

Compound ID	1322
Compound Structure
Plant Source	Byrsonima crassa Common Name:
Source Family	Malpighiaceae
Origin	Brazil
Plant Part Used	Bark
Extract
Target Bacteria	Mycobacterium tuberculosis H37Rv (ATCC 27 294)
Assay / Test Done	Microplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)	Isoniazid (0.015 - 0.05 µg/ml)
Inhibition [%]	90 %
Activity [MIC] µg/ml	1000 µg/ml
Activity (In terms of dilution)	1:25 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Treatment of gastric disorders, diarrhea and infections
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Pavan FR, Sato DN, Higuchi CT, Santos ACB, Vilegas W, Leite CQE 2009. In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants. Rev Bras Farmacogn 19: 204-206
Curator

Record - 15 of 70 [TOP]

Compound ID	1323
Compound Structure
Plant Source	Byrsonima fagifolia Common Name:
Source Family	Malpighiaceae
Origin	Brazil
Plant Part Used	Leaf
Extract	Chloroform
Target Bacteria	Mycobacterium tuberculosis H37Rv (ATCC 27 294)
Assay / Test Done	Microplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)	Isoniazid (0.015 - 0.05 µg/ml)
Inhibition [%]	90 %
Activity [MIC] µg/ml	62.5 µg/ml
Activity (In terms of dilution)	1:25 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Tuberculosis
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Pavan FR, Sato DN, Higuchi CT, Santos ACB, Vilegas W, Leite CQE 2009. In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants. Rev Bras Farmacogn 19: 204-206
Curator

Record - 16 of 70 [TOP]

Compound ID	1324
Compound Structure
Plant Source	Byrsonima fagifolia Common Name:
Source Family	Malpighiaceae
Origin	Brazil
Plant Part Used	Leaf
Extract	Methanol
Target Bacteria	Mycobacterium tuberculosis H37Rv (ATCC 27 294)
Assay / Test Done	Microplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)	Isoniazid (0.015 - 0.05 µg/ml)
Inhibition [%]	90 %
Activity [MIC] µg/ml	500 µg/ml
Activity (In terms of dilution)	1:25 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Tuberculosis
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Pavan FR, Sato DN, Higuchi CT, Santos ACB, Vilegas W, Leite CQE 2009. In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants. Rev Bras Farmacogn 19: 204-206
Curator

Record - 17 of 70 [TOP]

Compound ID	1325
Compound Structure
Plant Source	Byrsonima intermedia Common Name:Murici
Source Family	Malpighiaceae
Origin	Brazil
Plant Part Used	Leaf
Extract	Chloroform
Target Bacteria	Mycobacterium tuberculosis H37Rv (ATCC 27 294)
Assay / Test Done	Microplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)	Isoniazid (0.015 - 0.05 µg/ml)
Inhibition [%]	90 %
Activity [MIC] µg/ml	250 µg/ml
Activity (In terms of dilution)	1:25 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Tuberculosis
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Pavan FR, Sato DN, Higuchi CT, Santos ACB, Vilegas W, Leite CQE 2009. In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants. Rev Bras Farmacogn 19: 204-206
Curator

Record - 18 of 70 [TOP]

Compound ID	1326
Compound Structure
Plant Source	Byrsonima intermedia Common Name:Murici
Source Family	Malpighiaceae
Origin	Brazil
Plant Part Used	Leaf
Extract	Methanol
Target Bacteria	Mycobacterium tuberculosis H37Rv (ATCC 27 294)
Assay / Test Done	Microplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)	Isoniazid (0.015 - 0.05 µg/ml)
Inhibition [%]	90 %
Activity [MIC] µg/ml	2000 µg/ml
Activity (In terms of dilution)	1:25 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Tuberculosis
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Pavan FR, Sato DN, Higuchi CT, Santos ACB, Vilegas W, Leite CQE 2009. In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants. Rev Bras Farmacogn 19: 204-206
Curator

Record - 19 of 70 [TOP]

Compound ID	1331
Compound Structure
Plant Source	Caesalpinia ferrea Common Name:Brazilian Ironwood, Ironwood, Leopard Tree
Source Family	Cyperaceae
Origin	Brazil
Plant Part Used	Leaf
Extract	Methanol
Target Bacteria	Mycobacterium tuberculosis H37Rv (ATCC 27 294)
Assay / Test Done	Microplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)	Isoniazid (0.015 - 0.05 µg/ml)
Inhibition [%]	90 %
Activity [MIC] µg/ml	4000 µg/ml
Activity (In terms of dilution)	1:25 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Tuberculosis
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Pavan FR, Sato DN, Higuchi CT, Santos ACB, Vilegas W, Leite CQE 2009. In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants. Rev Bras Farmacogn 19: 204-206
Curator

Record - 20 of 70 [TOP]

Compound ID	1458
Compound Structure
Plant Source	Cissus suscicaulis Common Name:
Source Family	Vitaceae
Origin	Brazil
Plant Part Used	Leaf
Extract	Chloroform
Target Bacteria	Mycobacterium tuberculosis H37Rv (ATCC 27 294)
Assay / Test Done	Microplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)	Isoniazid (0.015 - 0.05 µg/ml)
Inhibition [%]	90 %
Activity [MIC] µg/ml	62.5 µg/ml
Activity (In terms of dilution)	1:25 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Tuberculosis
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Pavan FR, Sato DN, Higuchi CT, Santos ACB, Vilegas W, Leite CQE 2009. In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants. Rev Bras Farmacogn 19: 204-206
Curator

Record - 21 of 70 [TOP]

Compound ID	1575
Compound Structure
Plant Source	Curatella americana Common Name:Andpapper Tree, Sandpaper Tree
Source Family	Dilleniaceae
Origin	Brazil
Plant Part Used	Bark
Extract	Chloroform
Target Bacteria	Mycobacterium tuberculosis H37Rv (ATCC 27 294)
Assay / Test Done	Microplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)	Isoniazid (0.015 - 0.05 µg/ml)
Inhibition [%]	90 %
Activity [MIC] µg/ml	62.5 µg/ml
Activity (In terms of dilution)	1:25 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Tuberculosis
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Pavan FR, Sato DN, Higuchi CT, Santos ACB, Vilegas W, Leite CQE 2009. In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants. Rev Bras Farmacogn 19: 204-206 2) http://zipcodezoo.com/Plants/C/Curatella_americana/
Curator

Record - 22 of 70 [TOP]

Compound ID	1576
Compound Structure
Plant Source	Curatella americana Common Name:Andpapper Tree, Sandpaper Tree
Source Family	Dilleniaceae
Origin	Brazil
Plant Part Used	Bark
Extract	Methanol
Target Bacteria	Mycobacterium tuberculosis H37Rv (ATCC 27 294)
Assay / Test Done	Microplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)	Isoniazid (0.015 - 0.05 µg/ml)
Inhibition [%]	90 %
Activity [MIC] µg/ml	500 µg/ml
Activity (In terms of dilution)	1:25 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Tuberculosis
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Pavan FR, Sato DN, Higuchi CT, Santos ACB, Vilegas W, Leite CQE 2009. In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants. Rev Bras Farmacogn 19: 204-206
Curator

Record - 23 of 70 [TOP]

Compound ID	1593
Compound Structure
Plant Source	Davilla elliptica Common Name:
Source Family	Dilleniaceae
Origin	Brazil
Plant Part Used	Leaf
Extract	Chloroform
Target Bacteria	Mycobacterium tuberculosis H37Rv (ATCC 27 294)
Assay / Test Done	Microplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)	Isoniazid (0.015 - 0.05 µg/ml)
Inhibition [%]	90 %
Activity [MIC] µg/ml	62.5 µg/ml
Activity (In terms of dilution)	1:25 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Tuberculosis
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Pavan FR, Sato DN, Higuchi CT, Santos ACB, Vilegas W, Leite CQE 2009. In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants. Rev Bras Farmacogn 19: 204-206
Curator

Record - 24 of 70 [TOP]

Compound ID	1594
Compound Structure
Plant Source	Davilla elliptica Common Name:
Source Family	Dilleniaceae
Origin	Brazil
Plant Part Used	Leaf
Extract	Methanol
Target Bacteria	Mycobacterium tuberculosis H37Rv (ATCC 27 294)
Assay / Test Done	Microplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)	Isoniazid (0.015 - 0.05 µg/ml)
Inhibition [%]	90 %
Activity [MIC] µg/ml	4000 µg/ml
Activity (In terms of dilution)	1:25 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Tuberculosis
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Pavan FR, Sato DN, Higuchi CT, Santos ACB, Vilegas W, Leite CQE 2009. In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants. Rev Bras Farmacogn 19: 204-206
Curator

Record - 25 of 70 [TOP]

Compound ID	1595
Compound Structure
Plant Source	Davilla nitida Common Name:
Source Family	Dilleniaceae
Origin	Brazil
Plant Part Used	Leaf
Extract	Chloroform
Target Bacteria	Mycobacterium tuberculosis H37Rv (ATCC 27 294)
Assay / Test Done	Microplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)	Isoniazid (0.015 - 0.05 µg/ml)
Inhibition [%]	90 %
Activity [MIC] µg/ml	125 µg/ml
Activity (In terms of dilution)	1:25 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Tuberculosis
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Pavan FR, Sato DN, Higuchi CT, Santos ACB, Vilegas W, Leite CQE 2009. In vitro anti-Mycobacterium tuberculosis activity of some Brazilian "Cerrado" plants. Rev Bras Farmacogn 19: 204-206
Curator

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