| Compound ID | 1631 |
| Compound Structure | |
| Plant Source | Equisetum arvense L. Common Name:Field Horsetail (English), Ashwa - Puchha (Sanskrit) |
| Source Family | Equisetaceae |
| Origin | India, Britain and Northern temperate region |
| Plant Part Used | Leaf |
| Extract | Methanol |
| Target Bacteria | Mycobacterium avium |
| Assay / Test Done | Micro Broth Dilution Method |
| Positive Control Used (conc.) | Streptomycin (IC50 value 1.14 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | > 500 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Recommended and effective in treatment of tuberculosis by older herbalists. Proved very effectual in spitting of blood. |
| PubMed ID [Source Literature] | 11744296 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Newton SM, Lau C, Gurcha SS, Besra GS, Wright CW.The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis.J Ethnopharmacol. 2002 Jan;79(1):57-67
|
| Curator | |
| Compound ID | 1632 |
| Compound Structure | |
| Plant Source | Equisetum arvense L. Common Name:Field Horsetail (English), Ashwa - Puchha (Sanskrit) |
| Source Family | Equisetaceae |
| Origin | India, Britain and Northern temperate region |
| Plant Part Used | Leaf |
| Extract | Methanol |
| Target Bacteria | Mycobacterium smegmatis |
| Assay / Test Done | Micro Broth Dilution Method |
| Positive Control Used (conc.) | Streptomycin (IC50 value 0.17 µg.ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | > 500 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Recommended and effective in treatment of tuberculosis by older herbalists. Proved very effectual in spitting of blood. |
| PubMed ID [Source Literature] | 11744296 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Newton SM, Lau C, Gurcha SS, Besra GS, Wright CW.The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis.J Ethnopharmacol. 2002 Jan;79(1):57-67
|
| Curator | |
| Compound ID | 1633 |
| Compound Structure | |
| Plant Source | Equisetum arvense L. Common Name:Field Horsetail (English), Ashwa - Puchha (Sanskrit) |
| Source Family | Equisetaceae |
| Origin | India, Britain and Northern temperate region |
| Plant Part Used | Leaf |
| Extract | Water |
| Target Bacteria | Mycobacterium tuberculosis |
| Assay / Test Done | Broth Dilution Assay |
| Positive Control Used (conc.) | |
| Inhibition [%] | |
| Activity [MIC] µg/ml | < 1:40 dilution |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Recommended and effective in treatment of tuberculosis by older herbalists. Proved very effectual in spitting of blood. |
| PubMed ID [Source Literature] | 11744296 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Newton SM, Lau C, Gurcha SS, Besra GS, Wright CW.The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis.J Ethnopharmacol. 2002 Jan;79(1):57-67
2) Fitzpatrick, F.K., 1954. Plant substances active against Mycobacterium tuberculosis. Antibiotics and Chemotherapy 4, 528–536.
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| Curator | |
| Compound ID | 2776 |
| Compound Structure | |
| Plant Source | Verbascum thapsus L. Common Name:Cow's Lungwort, Common Mullein, Aaron's Rod (English), Ban Tambaaku, Gidar Tambaaku, Phullaa (Sanskrit) |
| Source Family | Scrophulariaceae |
| Origin | Britain, Europe, Temperate Asia, North America, India |
| Plant Part Used | Flower, leaf |
| Extract | Methanol |
| Target Bacteria | Mycobacterium smegmatis |
| Assay / Test Done | Micro Broth Dilution Method |
| Positive Control Used (conc.) | |
| Inhibition [%] | |
| Activity [MIC] µg/ml | > 500 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Expectorant, bronchitis, phthisis, cough, consumption, asthma, pulmonary diseases |
| PubMed ID [Source Literature] | 11744296 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Newton SM, Lau C, Gurcha SS, Besra GS, Wright CW.The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis.J Ethnopharmacol. 2002 Jan;79(1):57-67
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| Curator | |
| Compound ID | 2777 |
| Compound Structure | |
| Plant Source | Verbascum thapsus L. Common Name:Cow's Lungwort, Common Mullein, Aaron's Rod (English), Ban Tambaaku, Gidar Tambaaku, Phullaa (Sanskrit) |
| Source Family | Scrophulariaceae |
| Origin | Britain, Europe, Temperate Asia, North America, India |
| Plant Part Used | Flower, leaf |
| Extract | Methanol |
| Target Bacteria | Mycobacterium avium |
| Assay / Test Done | Micro Broth Dilution Method |
| Positive Control Used (conc.) | |
| Inhibition [%] | |
| Activity [MIC] µg/ml | > 500 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Expectorant, bronchitis, phthisis, cough, consumption, asthma, pulmonary diseases |
| PubMed ID [Source Literature] | 11744296 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Newton SM, Lau C, Gurcha SS, Besra GS, Wright CW.The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis.J Ethnopharmacol. 2002 Jan;79(1):57-67
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| Curator | |
| Compound ID | 2778 |
| Compound Structure | |
| Plant Source | Verbascum thapsus L. Common Name:Cow's Lungwort, Common Mullein, Aaron's Rod (English), Ban Tambaaku, Gidar Tambaaku, Phullaa (Sanskrit) |
| Source Family | Scrophulariaceae |
| Origin | Britain, Europe, Temperate Asia, North America, India |
| Plant Part Used | Leaf |
| Extract | Water |
| Target Bacteria | Mycobacterium tuberculosis |
| Assay / Test Done | Broth Dilution Assay |
| Positive Control Used (conc.) | |
| Inhibition [%] | < 1:40 dilution |
| Activity [MIC] µg/ml | |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Expectorant, bronchitis, phthisis, cough, consumption, asthma, pulmonary diseases |
| PubMed ID [Source Literature] | 17276637 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34
2) Sharma, P.K., Dhyani, S.K., Shanker,V., 1979. Some useful and medicinal plants of the district Dehradun and Siwalik. Journal of Science Research in Plant Medicine 1, 17–43.
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| Curator | |
| Compound ID | 2779 |
| Compound Structure | |
| Plant Source | Verbascum thapsus L. Common Name:Cow's Lungwort, Common Mullein, Aaron's Rod (English), Ban Tambaaku, Gidar Tambaaku, Phullaa (Sanskrit) |
| Source Family | Scrophulariaceae |
| Origin | Britain, Europe, Temperate Asia, North America, India |
| Plant Part Used | Leaf |
| Extract | Methanol |
| Target Bacteria | Mycobacterium phlei |
| Assay / Test Done | Disk Diffusion Assay |
| Positive Control Used (conc.) | Gentamicin (10 µg/Disc) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | 8.0 mm, 10.0 mm at 2 g/ml, control (> 25 mm) |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Expectorant, bronchitis, phthisis, cough, consumption, asthma, pulmonary diseases |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) McCutcheon AR, Ellis SM, Hancock RE, Towers GH.Antibiotic screening of medicinal plants of the British Columbian native peoples.J Ethnopharmacol. 1992 Oct;37(3):213-23
2) Sharma, P.K., Dhyani, S.K., Shanker,V., 1979. Some useful and medicinal plants of the district Dehradun and Siwalik. Journal of Science Research in Plant Medicine 1, 17–43.
|
| Curator | |
| Compound ID | 2789 |
| Compound Structure | |
| Plant Source | Viola odorata Linn. Common Name:Sweet Violet (English) |
| Source Family | Violaceae |
| Origin | Europe including Britain, Northern Asia, North Tropical and South America, India |
| Plant Part Used | Leaf |
| Extract | Methanol (14.35 %) |
| Target Bacteria | Mycobacterium aurum |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Streptomycin (IC50 value 1.14) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | > 500 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Antiseptic, expectorant and used to treat cough, bronchitis, catarrh, flowers were used to treat consumption in the days of Charles II and were sold by all apothecaries |
| PubMed ID [Source Literature] | 11744296 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Newton SM, Lau C, Gurcha SS, Besra GS, Wright CW.The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis.J Ethnopharmacol. 2002 Jan;79(1):57-67
2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 1–4. Lalit Mohan Basu, Allahabad, India
|
| Curator | |
| Compound ID | 2790 |
| Compound Structure | |
| Plant Source | Viola odorata Linn. Common Name:Sweet Violet (English) |
| Source Family | Violaceae |
| Origin | Europe including Britain, Northern Asia, North Tropical and South America, India |
| Plant Part Used | Leaf |
| Extract | Methanol (14.35 %) |
| Target Bacteria | Mycobacterium smegmatis |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Streptomycin (IC50 value 0.17) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | > 500 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Antiseptic, expectorant and used to treat cough, bronchitis, catarrh, the flowers were used to treat consumption in the days of Charles II and were sold by all apothecaries |
| PubMed ID [Source Literature] | 11744296 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Newton SM, Lau C, Gurcha SS, Besra GS, Wright CW.The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis.J Ethnopharmacol. 2002 Jan;79(1):57-67
2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 1–4. Lalit Mohan Basu, Allahabad, India
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| Curator | |
