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Compound ID3952
Compound StructureN/A
Plant SourceKnema gluaca     Common Name:NR
Source FamilyMyristicaceae
OriginEvergreen forests in Thailand
Plant Part UsedFruit, leaf, stem
ExtractNR
Target BacteriaMycobacterium tuberculosis H37Ra
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)Isoniazid (0.05 µg/ml) and Kanamycin sulphate (1.25 µg/ml)
Inhibition [%]NR
Activity [MIC] µg/mlNR
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound IdentifiedAcyclic diterpene, glaucaic acid and acyl phenols
PubChem IDNR
Ethnomedicinal InformationNR
PubMed ID [Source Literature]19471882
Extract PreparationThe dried and milled fruits (350 g), leaves (570 g) and stems (700 g) of Knema glauca were separately macerated with n - hexane (5 × 3 l), EtOAc (5 × 3 l) and MeOH (5 × 3 l), respectively
Chemical Classification [Active Compound]Mixture
Media / Broth Used [Antimicrobial Assay/Test]NR
Cytotoxicity Assay [AID]Resazurin microplate assay
Reference(s)1) Rangkaew N, Suttisri R, Moriyasu M, Kawanishi K.A new acyclic diterpene acid and bioactive compounds from Knema glauca.Arch Pharm Res. 2009 May;32(5):685-92. Epub 2009 May 27

CuratorKeyaMukherjee, Swati Gandhi


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