| Compound ID | 3952 |
| Compound Structure | N/A |
| Plant Source | Knema gluaca Common Name:NR |
| Source Family | Myristicaceae |
| Origin | Evergreen forests in Thailand |
| Plant Part Used | Fruit, leaf, stem |
| Extract | NR |
| Target Bacteria | Mycobacterium tuberculosis H37Ra |
| Assay / Test Done | Microplate Alamar Blue Assay (MABA) |
| Positive Control Used (conc.) | Isoniazid (0.05 µg/ml) and Kanamycin sulphate (1.25 µg/ml) |
| Inhibition [%] | NR |
| Activity [MIC] µg/ml | NR |
| Activity (In terms of dilution) | NR |
| Activity (Zone of inhibition in mm) | NR |
| Active Compound Identified | Acyclic diterpene, glaucaic acid and acyl phenols |
| PubChem ID | NR |
| Ethnomedicinal Information | NR |
| PubMed ID [Source Literature] | 19471882 |
| Extract Preparation | The dried and milled fruits (350 g), leaves (570 g) and stems (700 g) of Knema glauca were separately macerated with n - hexane (5 × 3 l), EtOAc (5 × 3 l) and MeOH (5 × 3 l), respectively |
| Chemical Classification [Active Compound] | Mixture |
| Media / Broth Used [Antimicrobial Assay/Test] | NR |
| Cytotoxicity Assay [AID] | Resazurin microplate assay |
| Reference(s) | 1) Rangkaew N, Suttisri R, Moriyasu M, Kawanishi K.A new acyclic diterpene acid and bioactive compounds from Knema glauca.Arch Pharm Res. 2009 May;32(5):685-92. Epub 2009 May 27
|
| Curator | KeyaMukherjee, Swati Gandhi |