| Compound ID | 1229 |
| Compound Structure | |
| Plant Source | Azadirachta indica A.juss. Common Name:Neem Tree, Margosa Tree (English), Nimba, Nimbaka (Sanskrit) |
| Source Family | Meliaceae |
| Origin | India, Kenya |
| Plant Part Used | Leaf |
| Extract | Methanol |
| Target Bacteria | Mycobacterium avium |
| Assay / Test Done | Micro Broth Dilution Method |
| Positive Control Used (conc.) | Streptomycin (IC50 value 1.14) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | > 500 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Cough, asthma, consumption, phthisis, tuberculosis, anthelmintic, antiseptic. Used to treat chronic leprosy, skin diseases, intestinal worms, chronic malaria fevers, small pox, syphylictic sores |
| PubMed ID [Source Literature] | 11744296 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Newton SM, Lau C, Gurcha SS, Besra GS, Wright CW.The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis.J Ethnopharmacol. 2002 Jan;79(1):57-67
2) Rao, R.R.Ethnobotanical studies on the flora of Meghalaya -- Some interesting reports of herbal medicines.1981, S.K. Jain (Ed.), 137-148
|
| Curator | |
| Compound ID | 1230 |
| Compound Structure | |
| Plant Source | Azadirachta indica A.juss. Common Name:Neem Tree, Margosa Tree (English), Nimba, Nimbaka (Sanskrit) |
| Source Family | Meliaceae |
| Origin | India, Kenya |
| Plant Part Used | Leaf |
| Extract | Methanol |
| Target Bacteria | Mycobacterium smegmatis |
| Assay / Test Done | Micro Broth Dilution Method |
| Positive Control Used (conc.) | Streptomycin (IC50 value 0.17) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | > 500 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Cough, asthma, consumption, phthisis, tuberculosis, anthelmintic, antiseptic. Used to treat chronic leprosy, skin diseases, intestinal worms, chronic malaria fevers, small pox, syphylictic sores |
| PubMed ID [Source Literature] | 11744296 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Newton SM, Lau C, Gurcha SS, Besra GS, Wright CW.The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis.J Ethnopharmacol. 2002 Jan;79(1):57-67
2) Rao, R.R.Ethnobotanical studies on the flora of Meghalaya -- Some interesting reports of herbal medicines.1981, S.K. Jain (Ed.), 137-148
|
| Curator | |
| Compound ID | 1231 |
| Compound Structure | |
| Plant Source | Azadirachta indica A.juss. Common Name:Neem Tree, Margosa Tree (English), Nimba, Nimbaka (Sanskrit) |
| Source Family | Meliaceae |
| Origin | India, Kenya |
| Plant Part Used | Stem bark |
| Extract | Methanol |
| Target Bacteria | Mycobacterium tuberculosis, Mycobacterium avian, Mycobacterium chelonae, Mycobacterium intracellulare, Mycobacterium tarrae |
| Assay / Test Done | Broth Dilution Assay |
| Positive Control Used (conc.) | |
| Inhibition [%] | 10 % |
| Activity [MIC] µg/ml | 8000 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Cough, asthma, consumption, phthisis, tuberculosis, anthelmintic, antiseptic. Used to treat chronic leprosy, skin diseases, intestinal worms, chronic malaria fevers, small pox, syphylictic sores |
| PubMed ID [Source Literature] | 9533435 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Fabry W, Okemo PO, Ansorg R.Antibacterial activity of East African medicinal plants.J Ethnopharmacol. 1998 Feb;60(1):79-84
|
| Curator | |
| Compound ID | 1374 |
| Compound Structure | |
| Plant Source | Carissa edulis Vahl Common Name:Carrisse, Carandas Plum |
| Source Family | Apocynaceae |
| Origin | Kenya |
| Plant Part Used | Root |
| Extract | Methanol |
| Target Bacteria | Mycobacterium tuberculosis |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2,1 and 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 2 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Polio, tuberculosis, asthma, gonorrhea, malaria |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
|
| Curator | |
| Compound ID | 1375 |
| Compound Structure | |
| Plant Source | Carissa edulis Vahl Common Name:Carrisse, Carandas plum |
| Source Family | Apocynaceae |
| Origin | Kenya |
| Plant Part Used | Root |
| Extract | Methanol |
| Target Bacteria | Mycobacterium kansasii |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2, 1 and 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 2000 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Polio, tuberculosis, asthma, gonorrhea, malaria |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
|
| Curator | |
| Compound ID | 1376 |
| Compound Structure | |
| Plant Source | Carissa edulis Vahl Common Name:Carrisse, Carandas Plum |
| Source Family | Apocynaceae |
| Origin | Kenya |
| Plant Part Used | Root |
| Extract | Methanol |
| Target Bacteria | Mycobacterium fortuitum |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2, 1 and 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 0.5, 1 and 2 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Polio, tuberculosis, asthma, gonorrhea, malaria |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
|
| Curator | |
| Compound ID | 1377 |
| Compound Structure | |
| Plant Source | Carissa edulis Vahl Common Name:Carrisse, Carandas Plum |
| Source Family | Apocynaceae |
| Origin | Kenya |
| Plant Part Used | Root |
| Extract | Methanol |
| Target Bacteria | Mycobacterium smegmatis |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2, 1 and 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 0.5, 1 and 2 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Polio, tuberculosis, asthma, gonorrhea, malaria |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
|
| Curator | |
| Compound ID | 1488 |
| Compound Structure | |
| Plant Source | Clerodendrum myricoides (Hochst)Vatke Common Name:Butterfly Bush, Blue Glory Bower |
| Source Family | Verbenaceae |
| Origin | Kenya |
| Plant Part Used | Root |
| Extract | Methanol |
| Target Bacteria | Mycobacterium tuberculosis |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2, 1 and 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 1, 2 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Gonorrhea, mumps, tuberculosis, chest problems, hepatitis |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
|
| Curator | |
| Compound ID | 1489 |
| Compound Structure | |
| Plant Source | Clerodendrum myricoides (Hochst)Vatke Common Name:Butterfly Bush, Blue Glory Bower |
| Source Family | Verbenaceae |
| Origin | Kenya |
| Plant Part Used | Root |
| Extract | Methanol |
| Target Bacteria | Mycobacterium kansasii |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2, 1 and 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 2 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Gonorrhea, mumps, tuberculosis, chest problems, hepatitis |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
|
| Curator | |
| Compound ID | 1490 |
| Compound Structure | |
| Plant Source | Clerodendrum myricoides (Hochst)Vatke Common Name:Butterfly Bush, Blue Glory Bower |
| Source Family | Verbenaceae |
| Origin | Kenya |
| Plant Part Used | Root |
| Extract | Methanol |
| Target Bacteria | Mycobacterium fortuitum |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2, 1 and 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 1, 2 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Gonorrhea, mumps, tuberculosis, chest problems, hepatitis |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
|
| Curator | |
| Compound ID | 1491 |
| Compound Structure | |
| Plant Source | Clerodendrum myricoides (Hochst)Vatke Common Name:Butterfly Bush, Blue Glory Bower |
| Source Family | Verbenaceae |
| Origin | Kenya |
| Plant Part Used | Root |
| Extract | Methanol |
| Target Bacteria | Mycobacterium smegmatis |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2, 1 and 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 1, 2 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Gonorrhea, mumps, tuberculosis, chest problems, hepatitis |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Richard M. Mariita, Paul O. Okemo , John A. Orodho, Claude Kirimuhuzya , Joseph N. Otieno ,Magadula J. Joseph EFFICACY OF 13 MEDICINAL PLANTS USED BY INDIGENOUS COMMUNITIES AROUND LAKE VICTORIA, KENYA, AGAINST TUBERCULOSIS, DIARRHOEA CAUSING BACTERIA AND CANDIDA ALBICANS International Journal Of Pharmacy&Technology ISSN: 0975-766X Available Online through Research Article www.ijptonline.com
|
| Curator | |
| Compound ID | 1557 |
| Compound Structure | |
| Plant Source | Croton macrostachyus Hochst. ex Ferret et Galinier Common Name:Broad - Leaved Croton |
| Source Family | Euphorbiaceae |
| Origin | Kenya |
| Plant Part Used | Stem bark |
| Extract | Methanol |
| Target Bacteria | Mycobacterium tuberculosis |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2, 1 and 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 2 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Stomach ache, tuberculosis, asthma, coughs, rheumatism |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
2) http://www.fao.org/docrep/x5327e/x5327e07.htm
|
| Curator | |
| Compound ID | 1558 |
| Compound Structure | |
| Plant Source | Croton macrostachyus Hochst. ex Ferret et Galinier Common Name:Broad - Leaved Croton |
| Source Family | Euphorbiaceae |
| Origin | Kenya |
| Plant Part Used | Stem bark |
| Extract | Methanol |
| Target Bacteria | Mycobacterium kansasii |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2, 1 and 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 0.5, 1, 2 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Stomach ache, tuberculosis, asthma, coughs, rheumatism |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
2) http://www.fao.org/docrep/x5327e/x5327e07.htm
|
| Curator | |
| Compound ID | 1559 |
| Compound Structure | |
| Plant Source | Croton macrostachyus Hochst. ex Ferret et Galinier Common Name:Broad - Leaved Croton |
| Source Family | Euphorbiaceae |
| Origin | Kenya |
| Plant Part Used | Stem bark |
| Extract | Methanol |
| Target Bacteria | Mycobacterium fortuitum |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2, 1 and 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 2000 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Stomach ache, tuberculosis, asthma, coughs, rheumatism |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
2) http://www.fao.org/docrep/x5327e/x5327e07.htm
|
| Curator | |
| Compound ID | 1560 |
| Compound Structure | |
| Plant Source | Croton macrostachyus Hochst. ex Ferret et Galinier Common Name:Broad - Leaved Croton |
| Source Family | Euphorbiaceae |
| Origin | Kenya |
| Plant Part Used | Stem bark |
| Extract | Methanol |
| Target Bacteria | Mycobacterium smegmatis |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2, 1 & 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 0.5, 1, 2 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Stomacha ache, tuberculosis, asthma, coughs, rheumatism |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
2) http://www.fao.org/docrep/x5327e/x5327e07.htm
|
| Curator | |
| Compound ID | 1628 |
| Compound Structure | |
| Plant Source | Entada abyssinica A. Rich Common Name:Tree Entanda |
| Source Family | Fabaceae |
| Origin | Kenya |
| Plant Part Used | Stem |
| Extract | Methanol |
| Target Bacteria | Mycobacterium tuberculosis, Mycobacterium avium, Mycobacterium intracellulare, Mycobacterium chelonae / chelonei, Mycobacterium terrae |
| Assay / Test Done | |
| Positive Control Used (conc.) | |
| Inhibition [%] | 10 % of the inoculum of the five mycobacterial species at 2 mg/ml |
| Activity [MIC] µg/ml | 0.5 - 4 mg/ml based on bacteria |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis |
| PubMed ID [Source Literature] | 9533435 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Fabry W, Okemo PO, Ansorg R.Antibacterial activity of East African medicinal plants.J Ethnopharmacol. 1998 Feb;60(1):79-84
|
| Curator | |
| Compound ID | 1647 |
| Compound Structure | |
| Plant Source | Erythrina abyssinica Lam ex DC Common Name:Lucky - Bean Tree, Red - Hot - Poker Tree (English), Munhimbiti, Mutsiti (Sanskrit) |
| Source Family | Fabaceae |
| Origin | Kenya |
| Plant Part Used | Bark, root |
| Extract | Methanol |
| Target Bacteria | Mycobacterium tuberculosis |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2,1 & 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 2 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis, malaria, stomach ache |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
2) http://www.zimbabweflora.co.zw/speciesdata/species.php?species_id=131450
|
| Curator | |
| Compound ID | 1648 |
| Compound Structure | |
| Plant Source | Erythrina abyssinica Lam ex DC Common Name:Lucky - Bean Tree, Red - Hot - Poker Tree (English), Munhimbiti, Mutsiti (Sanskrit) |
| Source Family | Fabaceae |
| Origin | Kenya |
| Plant Part Used | Bark, root |
| Extract | Methanol |
| Target Bacteria | Mycobacterium kansasii |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2, 1 and 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 2 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis, malaria, stomach ache |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
2) http://www.zimbabweflora.co.zw/speciesdata/species.php?species_id=131450
|
| Curator | |
| Compound ID | 1649 |
| Compound Structure | |
| Plant Source | Erythrina abyssinica Lam ex DC Common Name:Lucky - Bean Tree, Red - Hot - Poker Tree (English), Munhimbiti, Mutsiti (Sanskrit) |
| Source Family | Fabaceae |
| Origin | Kenya |
| Plant Part Used | Bark, root |
| Extract | Methanol |
| Target Bacteria | Mycobacterium fortuitum |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2, 1 and 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 2 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis, malaria, stomach ache |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
2) http://www.zimbabweflora.co.zw/speciesdata/species.php?species_id=131450
|
| Curator | |
| Compound ID | 1650 |
| Compound Structure | |
| Plant Source | Erythrina abyssinica Lam ex DC Common Name:Lucky - Bean Tree, Red - Hot - Poker Tree (English), Munhimbiti, Mutsiti (Sanskrit) |
| Source Family | Fabaceae |
| Origin | Kenya |
| Plant Part Used | Bark, root |
| Extract | Methanol |
| Target Bacteria | Mycobacterium smegmatis |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2, 1 and 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 2 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis, malaria, stomach ache |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
2) http://www.zimbabweflora.co.zw/speciesdata/species.php?species_id=131450
|
| Curator | |
| Compound ID | 1718 |
| Compound Structure | |
| Plant Source | Euphorbia tirucalli L. Common Name:Indian Tree Spurge, Milk Hedge, Petroleum - Plant, Aveloz, Milk Bush, Pencil Tree |
| Source Family | Euphorbiaceae |
| Origin | Kenya |
| Plant Part Used | Stem bark |
| Extract | Methanol |
| Target Bacteria | Mycobacterium tuberculosis |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2,1 & 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 2000 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis, asthma |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
|
| Curator | |
| Compound ID | 1719 |
| Compound Structure | |
| Plant Source | Euphorbia tirucalli L. Common Name:Indian Tree Spurge, Milk Hedge, Petroleum - plant, Aveloz, Milk bush, Pencil Tree |
| Source Family | Euphorbiaceae |
| Origin | Kenya |
| Plant Part Used | Stem |
| Extract | Methanol |
| Target Bacteria | Mycobacterium kansasii |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2,1 & 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 2000 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis, asthma |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
|
| Curator | |
| Compound ID | 1720 |
| Compound Structure | |
| Plant Source | Euphorbia tirucalli L. Common Name:Indian Tree Spurge, Milk Hedge, Petroleum - Plant, Aveloz, Milk Bush, Pencil Tree |
| Source Family | Euphorbiaceae |
| Origin | India, Kenya |
| Plant Part Used | Stem |
| Extract | Methanol |
| Target Bacteria | Mycobacterium fortuitum |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2,1 and 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 2000 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis, asthma |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
|
| Curator | |
| Compound ID | 1721 |
| Compound Structure | |
| Plant Source | Euphorbia tirucalli L. Common Name:Indian Tree Spurge, Milk Hedge, Petroleum - Plant, Aveloz, Milk Bush, Pencil Tree |
| Source Family | Euphorbiaceae |
| Origin | Kenya |
| Plant Part Used | Stem |
| Extract | Methanol |
| Target Bacteria | Mycobacterium smegmatis |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2,1 and 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 2 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis, asthma |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
|
| Curator | |
| Compound ID | 1776 |
| Compound Structure | |
| Plant Source | Fuerstia africana T.C.E.Fr. Common Name: |
| Source Family | Lamiaceae |
| Origin | Kenya |
| Plant Part Used | Leaf |
| Extract | Methanol |
| Target Bacteria | Mycobacterium tuberculosis |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2, 1 and 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 2000 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Malaria, asthma, chest problems |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
|
| Curator | |
